Výsledky vyhledávání - "Subhashree Kumaravel"

Akademický článek

Conjugated Bile Acids Promote Lymphangiogenesis by Modulation of the Reactive Oxygen Species–p90RSK–Vascular Endothelial Growth Factor Receptor 3 Pathway

Autor: Priyanka Banerjee, Subhashree Kumaravel, Sukanya Roy, Niyanshi Gaddam, Johnny Odeh, Kayla J. Bayless, Shannon Glaser, Sanjukta Chakraborty

Publikováno v: Cells, Vol 12, Iss 4, p 526 (2023)

Conjugated bile acids (BA) are significantly elevated in several liver pathologies and in the metastatic lymph node (LN). However, the effects of BAs on pathological lymphangiogenesis remains unknown. The current study explores the effects of BAs on

Externí odkaz: https://doaj.org/article/7108d2a56f2e4e4aa56e71bdceebe2cf

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Akademický článek

732 A novel nuclear receptor 4A1 (NR4A1) antagonists attenuates T-cell exhaustion in colorectal cancer

Autor: Maen Abdelrahim, Kumaravel Mohankumar, Stephen Safe, Gus Wright, Subhashree Kumaravel, Rupesh Shrestha, Robert Chapkin

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)

Externí odkaz: https://doaj.org/article/5cea1c94ba8443aba06104648b8d9345

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Akademický článek

Tumor Lymphatic Interactions Induce CXCR2-CXCL5 Axis and Alter Cellular Metabolism and Lymphangiogenic Pathways to Promote Cholangiocarcinoma

Autor: Sukanya Roy, Subhashree Kumaravel, Priyanka Banerjee, Tori K. White, April O’Brien, Catherine Seelig, Rahul Chauhan, Burcin Ekser, Kayla J. Bayless, Gianfranco Alpini, Shannon S. Glaser, Sanjukta Chakraborty

Publikováno v: Cells, Vol 10, Iss 11, p 3093 (2021)

Cholangiocarcinoma (CCA), or cancer of bile duct epithelial cells, is a very aggressive malignancy characterized by early lymphangiogenesis in the tumor microenvironment (TME) and lymph node (LN) metastasis which correlate with adverse patient outcom

Externí odkaz: https://doaj.org/article/d07c1d18d4ff4f769fd2064703464d10

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The β1-integrin plays a key role in LEC invasion in an optimized 3-D collagen matrix model

Autor: Subhashree Kumaravel, Colette A. Abbey, Kayla J. Bayless, Sanjukta Chakraborty

Publikováno v: American Journal of Physiology-Cell Physiology. 319:C1045-C1058

Lymphangiogenesis, or formation of new lymphatic vessels, is a tightly regulated process that is controlled by growth factor signaling and biomechanical cues. Lymphatic endothelial cells (LECs) undergo remodeling, migration, and proliferation to inva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::66d390b6a31e29fe76cb01bed271ef27
https://doi.org/10.1152/ajpcell.00299.2020

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Conjugated Bile Acids activate Reactive Oxygen Species‐p90RSK‐Vascular Endothelial Growth Factor Receptor 3 signaling axis to promote lymphangiogenesis

Autor: Priyanka Banerjee, Sukanya Roy, Subhashree Kumaravel, Niyanshi Gaddam, Johnny Odeh, Tori White, Heather Francis, Kayla Bayless, Gianfranco Alpini, Shannon Glaser, Sanjukta Chakraborty

Publikováno v: The FASEB Journal. 36

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::37642386928643b58993b2d8737ece77
https://doi.org/10.1096/fasebj.2022.36.s1.r5471

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Neuropeptide Substance P Enhances Inflammation-Mediated Tumor Signaling Pathways and Migration and Proliferation of Head and Neck Cancers

Autor: Sumeet Singh, Sukanya Roy, Subhashree Kumaravel, Sanjukta Chakraborty, Saurabh Dhole, Vani Pavan

Publikováno v: Indian J Surg Oncol

Head and neck cancers (HNC) are extremely aggressive, highly recurrent, and the sixth most common cancer worldwide. Neuropeptide substance P, along with its primary receptor, neurokinin-1 (NK-1R), is overexpressed in HNC and is a central player in in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25ecd1b434eea0cbb9750dfdeb64ad9a
https://doi.org/10.1007/s13193-020-01210-7

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Hypoxic tumor microenvironment: Implications for cancer therapy

Autor: Subhashree Kumaravel, Sanjukta Chakraborty, Ankith Sharma, Kayla J. Bayless, Camille L. Duran, Sukanya Roy

Publikováno v: Exp Biol Med (Maywood)

Hypoxia or low oxygen concentration in tumor microenvironment has widespread effects ranging from altered angiogenesis and lymphangiogenesis, tumor metabolism, growth, and therapeutic resistance in different cancer types. A large number of these effe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53d61b33d8e46324a3f04aad143a1851
https://doi.org/10.1177/1535370220934038

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