Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Subhash C. Taneja"'
Publikováno v:
Acta Crystallographica Section E, Vol 68, Iss 8, Pp o2594-o2594 (2012)
The title molecule, C18H24O12, has crystallographic 2/m symmetry with two acetate group located on a mirror plane. The H—Csp3—O—Csp2 torsion angles characterizing orientation of the acetyl groups with respect to the cyclohexane ring are 0.0, 23
Externí odkaz:
https://doaj.org/article/5c90abafd3bd4a048d2d17d6cae0169b
Autor:
Mubashir J. Mintoo, Abid Hamid, Mudassier Ahmad, Subhash C. Taneja, Parduman Raj Sharma, Priya Mahajan, Mohmmad Afzal Zargar, Ashok Kumar, Neena Capalash, Amit Nargotra, Ram A. Vishwakarma, Abdul Rouf, Javeed Ahmad Bhat, Mushtaq A. Aga, Brijesh Kumar, Dilip M. Mondhe, Bhahwal Ali Shah
Publikováno v:
Journal of Medicinal Chemistry. 60:3484-3497
l-Vasicine is a quinazoline alkaloid with an electron dense ring and additional functionalities in its structure. Employing target oriented synthesis (TOS) based on in silico studies, molecules with significant docking scores containing different der
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28a7ecb35ebf99f933b4bd584a3c10cf
https://doi.org/10.1021/acs.jmedchem.7b00322
https://doi.org/10.1021/acs.jmedchem.7b00322
Autor:
Sheikh Rayees, Anjna Sharma, Brijesh Kumar, Abdul Rouf, Mushtaq A. Aga, Gurdarshan Singh, P. Nagaraju, Subhash C. Taneja
Publikováno v:
Bioorganic & Medicinal Chemistry. 25:1440-1447
We report the chemical synthesis of Ofornine mimics from l-vasicine, structure-activity relationship studies and their in vivo screening for anti-hypertensive action in Wistar rats. It was observed that most of the analogs possessed anti-hypertensive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::776e79f0847b3bedd298efab5851bb21
https://doi.org/10.1016/j.bmc.2017.01.006
https://doi.org/10.1016/j.bmc.2017.01.006
Autor:
Ozair Alam, Surrinder Koul, Mohammed A. Alam, Amit Nargotra, Subhash C. Taneja, Md. Iqbal Alam
Publikováno v:
European Journal of Medicinal Chemistry. 114:209-219
In our earlier study, we have reported that a phenolic compound 2-hydroxy-4-methoxybenzaldehyde from Janakia arayalpatra root extract was active against Viper and Cobra envenomations. Based on the structure of this natural product, libraries of synth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca4572660e950716a568cb133804a448
https://doi.org/10.1016/j.ejmech.2016.03.008
https://doi.org/10.1016/j.ejmech.2016.03.008
Publikováno v:
Synthetic Communications. 46:361-366
A simple and short synthesis has been revealed for the preparation of (±) β-(Methoxy-(substitutedphenyl)-methyl)-γ-butyrolactones. The reaction of cinnamyl acetate with Mn(OAc)3 · 2H2O in boiling acetic acid containing acetic anhydride gave the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a2c6272adf256acc4859b031c706038
https://doi.org/10.1080/00397911.2016.1138497
https://doi.org/10.1080/00397911.2016.1138497
Publikováno v:
Helvetica Chimica Acta. 98:823-833
A new approach was proposed for the synthesis of 2-azido-1,3-diols from easily available and inexpensive chiral pool synthon (R)-2,3-O-cyclohexylidene-D-glyceraldehyde, through Mitsunobu azidation of 1,2-diols. Both C(2) and C(1) azides in variable r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67984025e688ba1ff4b533469345eae5
https://doi.org/10.1002/hlca.201400344
https://doi.org/10.1002/hlca.201400344
Autor:
Mushtaq A. Aga, Shashank K. Singh, Asif Khurshid Qazi, Abid Hamid, Saima Khan, Shakir Ali, Ajit Kumar Saxena, Akanksha Behl, Aashiq Hussain, Subhash C. Taneja, Dilip M. Mondhe, Bhahwal Ali Shah
Publikováno v:
Cancer Letters. 359:47-56
Deregulation of PI3K signalling pathway is strongly involved in pathology of cancer and development of resistance in tumour cells. Here, we report that pharmacologically active vasicinone analogue, RLX (7, 8, 9, 10-Tetrahydroazepino [2, 1-b] quinazol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::643e70996eaff62ba48000bfc653ba4b
https://doi.org/10.1016/j.canlet.2014.12.034
https://doi.org/10.1016/j.canlet.2014.12.034
Autor:
Kumar Vanka, Masood Ahmad Rizvi, Subhash C. Taneja, Arvind Kumar, Manoj V. Mane, Manjeet Kumar, Bhahwal Ali Shah
Publikováno v:
European Journal of Organic Chemistry. 2014:5247-5255
A tandem asymmetric cross-aldol reaction involving the in situ generation of acetaldehyde from vinyl acetate has been developed that may resolve the challenges associated with the handling of acetaldehyde. The simple protocol, mild reaction condition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a0127654bd8f67e82d944c2f6af9f2e
https://doi.org/10.1002/ejoc.201402551
https://doi.org/10.1002/ejoc.201402551
Publikováno v:
Journal of Molecular Catalysis B: Enzymatic. 101:35-39
(S)-1,1′-Binaphthyl-2,2′-diol was prepared in high optical purity (∼98%) via Arthrobacter sp. lipase (MTCC No. 5125) catalyzed kinetic resolution. The immobilization of the substrate on a solid inert support significantly improved the enantiose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::011cb4dc7f118461674e25db06d0aad0
https://doi.org/10.1016/j.molcatb.2013.12.014
https://doi.org/10.1016/j.molcatb.2013.12.014
Publikováno v:
RSC Adv.. 4:17206-17209
A common precursor strategy for the synthesis of bestatin hydrochloride, an anticancer agent, 1,3-diaminoalcohol, an amprenavir intermediate, and a syn-4-hydroxy-5-phenyl-γ-lactam intermediate of various bioactive molecules using an α,β-unsaturate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d747f0c32e411e847a31817373009da
https://doi.org/10.1039/c4ra00205a
https://doi.org/10.1039/c4ra00205a