Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Subhash C. Gautam"'
Autor:
Subhash C. Gautam, Ali S. Arbab, Nadimpalli R. S. Varma, Yongbo Liu, Xiaohua Gao, Dorrah Deeb
Publikováno v:
Molecules, Vol 18, Iss 3, Pp 3250-3265 (2013)
Methyl-2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oate (CDDO-Me) is a synthetic derivative of oleanolic acid, a triterpene, with apoptosis-inducing activity in a wide range of cancer cells. Induction of apoptosis by CDDO-Me is associated with the gener
Externí odkaz:
https://doaj.org/article/6a191f46f2224c8f91b0d4915e084065
Publikováno v:
Molecules, Vol 17, Iss 12, Pp 14795-14809 (2012)
Methyl-2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oate (CDDO-Me) is an synthetic oleanane triterpenoid with strong antiprolifertive and proapoptotic activities in cancer cells. However, the effect of CDDO-Me on human telomerase reverse transcriptase (h
Externí odkaz:
https://doaj.org/article/7aea0ad4e92845e4abcaf89c9466eeaa
Autor:
Jiajiu Shaw, Subhash C. Gautam, Dorrah Deeb, Xiaohua Gao, Yiguan Zhang, Yong Bo Liu, Frederick A. Valeriote
Publikováno v:
Oncology Reports. 37:1914-1920
Autor:
Jiajiu Shaw, Subhash C. Gautam, Yiguan Zhang, Xiaohua Gao, Dorrah Deeb, Yongbo Liu, Frederic K A Valeriote
Publikováno v:
International Journal of Oncology. 49:1139-1147
Pancreatic ductal adenocarcinoma (PDA) remains one of the most difficult to treat of all malignancies. Multimodality regimens provide only short-term symptomatic improvement with minor impact on survival, underscoring the urgent need for novel therap
Autor:
Xiaohua Gao, Subhash C. Gautam, Dorrah Deeb, Yiguan Zhang, Yongbo Liu, Patricia Liu, Jiajiu Shaw
Publikováno v:
International Journal of Oncology
Methyl-2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oate (CDDO-Me) has shown potent antitumorigenic activity against a wide range of cancer cell lines in vitro and inhibited the growth of liver, lung and prostate cancer in vivo. In the present study, we
Publikováno v:
Oncology Reports
Pristimerin (PM) is a promising anticancer agent that has exhibited strong antiproliferative and apoptosis-inducing activity in various types of cancer cells. In the present study, we investigated the role of telomerase in mediating the antitumor act
Autor:
Dorrah Deeb, Yiguan Zhang, Jiajiu Shaw, Subhash C. Gautam, Xiaohua Gao, Yong Bo Liu, Kirit Pindolia, Chris Brigolin
Publikováno v:
International Journal of Oncology
Pristimerin (PM), a quinonemethide triterpenoid, is a promising anticancer agent with potent antiproliferative and apoptosis-inducing activities against cancer cell lines. However, the anticancer activity and mechanisms of PM in prostate cancer cells
Publikováno v:
International Journal of Oncology
Lack of effective therapeutics for pancreatic cancer at the present time underscores the dire need for safe and effective agents for the treatment of this malignancy. In the present study, we have evaluated the anticancer activity and the mechanism o
Publikováno v:
Molecules (Basel, Switzerland)
Molecules, Vol 17, Iss 12, Pp 14795-14809 (2012)
Molecules; Volume 17; Issue 12; Pages: 14795-14809
Molecules, Vol 17, Iss 12, Pp 14795-14809 (2012)
Molecules; Volume 17; Issue 12; Pages: 14795-14809
Methyl-2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oate (CDDO-Me) is an synthetic oleanane triterpenoid with strong antiprolifertive and proapoptotic activities in cancer cells. However, the effect of CDDO-Me on human telomerase reverse transcriptase (h
Autor:
Yongbo, Liu, Xiaohua, Gao, Dorrah, Deeb, Yiguan, Zhang, Jiajiu, Shaw, Frederick A, Valeriote, Subhash C, Gautam
Publikováno v:
Journal of experimental therapeuticsoncology. 11(4)
Trichothecenes are powerful mycotoxins that inhibit protein synthesis and induce ribotoxic stress response in mammalian cells. Verrucarin A (VC-A) is a Type D macrocyclic mycotoxin which inhibits cell proliferation and induces apoptosis in cancer cel