Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Subhash B. Arya"'
Publikováno v:
PLoS Biology, Vol 19, Iss 7, p e3001271 (2021)
Leukotriene B4 (LTB4) is secreted by chemotactic neutrophils, forming a secondary gradient that amplifies the reach of primary chemoattractants. This strategy increases the recruitment range for neutrophils and is important during inflammation. Here,
Externí odkaz:
https://doaj.org/article/b9f81a5a33d24e92bdf7d59c2aca07b8
Publikováno v:
Nat Cell Biol
Neutrophils migrating towards chemoattractant gradients amplify their recruitment range by releasing the secondary chemoattractant leukotriene B(4) (LTB(4))(1,2). We previously demonstrated that LTB(4) and its synthesizing enzymes, the 5-lipoxygenase
Publikováno v:
PLoS Pathogens, Vol 13, Iss 10, p e1006700 (2017)
Salmonella enterica serovar typhimurium extensively remodels the host late endocytic compartments to establish its vacuolar niche within the host cells conducive for its replication, also known as the Salmonella-containing vacuole (SCV). By maintaini
Externí odkaz:
https://doaj.org/article/82e4a47f36144822a4fc1b6497245bd1
Publikováno v:
The FASEB Journal. 36
Publikováno v:
Nature Cell Biology. 24:1319-1319
Publikováno v:
The Journal of Cell Biology
Rab7 and Arl8b mediate vesicle transport and fusion with lysosomes. Marwaha et al. show that the Rab7 effector PLEKHM1 competes with PLEKHM2/SKIP for binding to Arl8b and that Arl8 mediates recruitment of the HOPS complex to PLEKHM1-positive vesicles
Publikováno v:
Bio-protocol. 8(24)
Macrophages are highly phagocytic cells that utilize various pathogen recognition receptors (PRRs) to recognize pathogen-associated molecular patterns (PAMPs). These PAMPs can be present within the microbe, such as bacterial CpG DNA, and are recogniz
Publikováno v:
Nature cell biology. 24(7)
Neutrophils migrating towards chemoattractant gradients amplify their recruitment range by releasing the secondary chemoattractant leukotriene B
Publikováno v:
The Journal of Biological Chemistry
ADP-ribosylation factor-like GTPase 11 (ARL11) is a cancer-predisposing gene that has remained functionally uncharacterized to date. In this study, we report that ARL11 is endogenously expressed in mouse and human macrophages and regulates their acti
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 13, Iss 10, p e1006700 (2017)
PLoS Pathogens, Vol 13, Iss 10, p e1006700 (2017)
Salmonella enterica serovar typhimurium extensively remodels the host late endocytic compartments to establish its vacuolar niche within the host cells conducive for its replication, also known as the Salmonella-containing vacuole (SCV). By maintaini