Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Subhankar P. Mandal"'
Autor:
Subhankar P. Mandal, Aakriti Garg, P. Prabitha, Ashish D. Wadhwani, Laxmi Adhikary, B. R. Prashantha Kumar
Publikováno v:
Chemistry Central Journal, Vol 12, Iss 1, Pp 1-21 (2018)
Abstract Background An alarming requirement for finding newer antidiabetic glitazones as agonists to PPARγ are on its utmost need from past few years as the side effects associated with the available drug therapy is dreadful. In this context, herein
Externí odkaz:
https://doaj.org/article/2c1e7dfb84b048c799bb6b36fb235684
Autor:
Antony Justin, Premkumar Ashwini, Jincy A. Jose, Victoria Jeyarani, S. P. Dhanabal, Chennu Manisha, Subhankar P. Mandal, Guru Bhavimani, P. Prabitha, S. Yuvaraj, B. R. Prashantha Kumar
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
The present study has planned to evaluate the neuroprotective activity of two novel glitazones in a neuroinflammatory rat model. Two novel glitazones were selected from an in-house virtual library of glitazones based on their docking scores against p
Externí odkaz:
https://doaj.org/article/cc3b8fe2fcde4d8188a33fe9020b504b
Publikováno v:
German Journal of Pharmaceuticals and Biomaterials, Vol 2, Iss 2, Pp 20-29 (2023)
Novel N-(4-alkyl-4-oxo-1,3-thiazolidin-3-yl)-2-(5-nitro-1H-benzimidazole-1-yl)acetamide derivatives were evaluated as M. tuberculosis transcription inhibitors using protein 3Q3S, by performing molecular docking and molecular dynamics studies. Twelve
Externí odkaz:
https://doaj.org/article/cf9c7c46dd3245d9b3949052bd1193cc
Publikováno v:
Polycyclic Aromatic Compounds. :1-25
Autor:
Sushma, Pradeep, Shashank M, Patil, Chandan, Dharmashekara, Anisha, Jain, Ramith, Ramu, Prithvi S, Shirahatti, Subhankar P, Mandal, Pruthvish, Reddy, Chandrashekar, Srinivasa, Sharanagouda S, Patil, Joaqúın, Ortega-Castro, Juan, Frau, Norma, Flores-Holgúın, Chandan, Shivamallu, Shiva Prasad, Kollur, Daniel, Glossman-Mitnik
Publikováno v:
Journal of biomolecular structuredynamics.
The spike (S) glycoprotein and nucleocapsid (N) proteins are the crucial pathogenic proteins of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2) virus during its interaction with the host. Even FDA-approved drugs like dexamethasone an
Autor:
Shashank M. Patil, Vasantha Kumar, Subhankar P. Mandal, Ramith Ramu, P. Sushma, V. B. Chandana Kumari, Prithvi S. Shirahatti
Publikováno v:
ChemistrySelect. 6:9637-9644
Autor:
C. Mallikarjunaswamy, V. Lakshmi Ranganatha, Subhankar P. Mandal, Shaukath Ara Khanum, Ramith Ramu, T. Prashanth
Publikováno v:
Journal of the Iranian Chemical Society. 18:2741-2756
The occurrence of drug-resistant bacterial infections impulses the development of new antibacterial agents that own a mechanism of action different from traditional antibiotics. From the earlier days, benzophenone, indole and benzimidazole moieties a
Autor:
Mahendra Gowdru Srinivasa, Natasha Naval Aggarwal, Banylla Felicity Dkhar Gatpoh, Madan Kumar Shankar, Kannika Byadarahalli Ravindranath, Pujar Gurubasavaraj Veeranna, Sheshagiri Dixit, Subhankar P. Mandal, Prashantha Kumar Bommenahally Ravanappa, Pukar Khanal, Revanasiddappa Bistuvalli Chandrashekarappa
Publikováno v:
Journal of molecular recognition : JMRREFERENCES. 35(8)
A novel series of benzothiazole-rhodanine derivatives (A1-A10) were designed and synthesized, with the aim of developing possible antidiabetic agents and the spectral characterization of these compounds was done using infrared spectroscopy (IR), prot
Autor:
Narasimha M Beeraka, Runze Zhou, Xiaoyan Wang, Hemanth Vikram P R, Tegginamath Pramod Kumar, Junqi Liu, M V Greeshma, Subhankar P Mandal, B M Gurupadayya, Ruitai Fan
Publikováno v:
International journal of nanomedicine. 17
Severe steroid-resistant asthma (SSR) patients do not respond to the corticosteroid therapies due to the heterogeneity, and genome-wide variations. However, there are very limited reports pertinent to the molecular signaling underlying SSR and making
Autor:
C. H. Sandhya, Jeyabalan Jeyaram Bharathi, Priya Durai, Antony Justin, S. Dhivya, Ashish Wadhwani, S. Divakar, Subhankar P. Mandal, Satheesh John Sekhar, Pradeep Kabadi, P. Prabitha, B. R. Prashantha Kumar, S. Yuvaraj
Publikováno v:
Neurotoxicity Research. 37:508-524
In the present study, two structurally diverse novel glitazones were designed and synthesized for activation of central PGC-1α signaling through stimulation of PPAR-γ receptor. The functional interaction between PGC-1α and PPAR-γ is a key interac