Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Subhankar, Mukhopadhyay"'
Autor:
Chinaemerem U. Onyishi, Guillaume E. Desanti, Alex L. Wilkinson, Samuel Lara-Reyna, Eva-Maria Frickel, Gyorgy Fejer, Olivier D. Christophe, Clare E. Bryant, Subhankar Mukhopadhyay, Siamon Gordon, Robin C. May
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract The opportunistic fungal pathogen Cryptococcus neoformans causes lethal infections in immunocompromised patients. Macrophages are central to the host response to cryptococci; however, it is unclear how C. neoformans is recognised and phagocy
Externí odkaz:
https://doaj.org/article/d574524e28824efda336edb4bafa128e
Autor:
Antoni Olona, Subhankar Mukhopadhyay, Charlotte Hateley, Fernando O. Martinez, Siamon Gordon, Jacques Behmoaras
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-10 (2021)
Abstract Cell membrane fusion and multinucleation in macrophages are associated with physiologic homeostasis as well as disease. Osteoclasts are multinucleated macrophages that resorb bone through increased metabolic activity resulting from cell fusi
Externí odkaz:
https://doaj.org/article/2fd5b548491e4a29a5558064d1059ef3
Autor:
Lyra O Randzavola, Paige M Mortimer, Emma Garside, Elizabeth R Dufficy, Andrea Schejtman, Georgia Roumelioti, Lu Yu, Mercedes Pardo, Kerstin Spirohn, Charlotte Tolley, Cordelia Brandt, Katherine Harcourt, Esme Nichols, Mike Nahorski, Geoff Woods, James C Williamson, Shreehari Suresh, John M Sowerby, Misaki Matsumoto, Celio XC Santos, Cher Shen Kiar, Subhankar Mukhopadhyay, William M Rae, Gordon J Dougan, John Grainger, Paul J Lehner, Michael A Calderwood, Jyoti Choudhary, Simon Clare, Anneliese Speak, Giorgia Santilli, Alex Bateman, Kenneth GC Smith, Francesca Magnani, David C Thomas
Publikováno v:
eLife, Vol 11 (2022)
EROS (essential for reactive oxygen species) protein is indispensable for expression of gp91phox, the catalytic core of the phagocyte NADPH oxidase. EROS deficiency in humans is a novel cause of the severe immunodeficiency, chronic granulomatous dise
Externí odkaz:
https://doaj.org/article/1b48b81ab31e44d4a2884318ac761009
Publikováno v:
Bio-Protocol, Vol 12, Iss 6 (2022)
As a model to interrogate human macrophage biology, macrophages differentiated from human induced pluripotent stem cells (hiPSCs) transcend other existing models by circumventing the variability seen in human monocyte-derived macrophages, whilst epit
Externí odkaz:
https://doaj.org/article/aa3ef321350943b38c50bd0d8db12671
Autor:
Grigory Ryzhakov, Nathaniel R. West, Fanny Franchini, Simon Clare, Nicholas E. Ilott, Stephen N. Sansom, Samuel J. Bullers, Claire Pearson, Alice Costain, Alun Vaughan-Jackson, Jeremy A. Goettel, Joerg Ermann, Bruce H. Horwitz, Ludovico Buti, Xin Lu, Subhankar Mukhopadhyay, Scott B. Snapper, Fiona Powrie
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
The Hiccs locus has been associated with susceptibility to colitis in mice. Here the authors identify a Hiccs locus gene encoding Alpha kinase 1 as a potent regulator of intestinal inflammation via modulation of the IL-12/Th1 axis.
Externí odkaz:
https://doaj.org/article/cd1515a1c0414a6e99b0e45f27672c4a
Autor:
Mridu Acharya, Anna Sokolovska, Jenny M. Tam, Kara L. Conway, Caroline Stefani, Fiona Raso, Subhankar Mukhopadhyay, Marianela Feliu, Elahna Paul, John Savill, Richard O. Hynes, Ramnik J. Xavier, Jatin M. Vyas, Lynda M. Stuart, Adam Lacy-Hulbert
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Integrins can regulate antigen-specific and innate immune receptor signalling, thereby affecting immune cell function. Here the authors show that avß3 integrin controls Toll-like receptor (TLR) signalling by regulating its trafficking to limit TLR-m
Externí odkaz:
https://doaj.org/article/dc8efeea8b80409f8e4a56aef9dd4da0
Autor:
Chinaemerem U. Onyishi, Guillaume E. Desanti, Alex L. Wilkinson, Gyorgy Fejer, Olivier D. Christophe, Clare E. Bryant, Subhankar Mukhopadhyay, Siamon Gordon, Robin C. May
The opportunistic fungal pathogenCryptococcus neoformanscauses lethal infections in immunocompromised patients. Macrophages are central to the host response to cryptococci; however, it is unclear howC. neoformansis recognized and phagocytosed by macr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c336b0aeb8af34d7dd8ab55ba1cfbf17
https://doi.org/10.1101/2023.01.30.525903
https://doi.org/10.1101/2023.01.30.525903
Autor:
Siamon Gordon, Matthew W.H. Chung, Scarlett L. Harris, Fernando Martinez-Estrada, Subhankar Mukhopadhyay
Publikováno v:
Encyclopedia of Cell Biology ISBN: 9780128216248
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d35194fbc0fc9d056bde5e05750fa1cd
https://doi.org/10.1016/b978-0-12-821618-7.00255-8
https://doi.org/10.1016/b978-0-12-821618-7.00255-8
Autor:
Alison E. Mather, Tu Le Thi Phuong, Yunfeng Gao, Simon Clare, Subhankar Mukhopadhyay, David A. Goulding, Nhu Tran Do Hoang, Ha Thanh Tuyen, Nguyen Phu Huong Lan, Corinne N. Thompson, Nguyen Hoang Thu Trang, Juan Carrique-Mas, Ngo Tri Tue, James I. Campbell, Maia A. Rabaa, Duy Pham Thanh, Katherine Harcourt, Ngo Thi Hoa, Nguyen Vinh Trung, Constance Schultsz, Gabriel G. Perron, John E. Coia, Derek J. Brown, Chinyere Okoro, Julian Parkhill, Nicholas R. Thomson, Nguyen Van Vinh Chau, Guy E. Thwaites, Duncan J. Maskell, Gordon Dougan, Linda J. Kenney, Stephen Baker
Publikováno v:
mBio, Vol 9, Iss 5 (2018)
ABSTRACT Nontyphoidal Salmonella (NTS), particularly Salmonella enterica serovar Typhimurium, is among the leading etiologic agents of bacterial enterocolitis globally and a well-characterized cause of invasive disease (iNTS) in sub-Saharan Africa. I
Externí odkaz:
https://doaj.org/article/3bbcd25618ea44648ab03b5e85d1b044
Autor:
Paige M Mortimer, Lyra O Randzavola, Emma Garside, Elizabeth R Dufficy, Andrea Schejtman, Georgia Roumelioti, Lu Yu, Mercedes Pardo, Kerstin Spirohn, Charlotte Tolley, Cordelia Brandt, Katherine Harcourt, Esme Nichols, Mike Nahorski, Geoff Woods, James C Williamson, Shreehari Suresh, John M Sowerby, Misaki Matsumoto, Celio XC Santos, Cher Shen Kiar, Subhankar Mukhopadhyay, William M Rae, Gordon J Dougan, John Grainger, Paul J Lehner, Michael A Calderwood, Jyoti Choudhary, Simon Clare, Anneliese Speak, Giorgia Santilli, Alex Bateman, Kenneth GC Smith, Francesca Magnani, David C Thomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ed7b8a23462d0bf93707f8ec4f553fd
https://doi.org/10.7554/elife.76387.sa2
https://doi.org/10.7554/elife.76387.sa2