Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Subhamoy Datta"'
Autor:
Ishani Morbia, Praveen Kumar, Aditi Lakshmi Satish, Akanksha Mudgal, Subhamoy Datta, Umashankar Singh
Publikováno v:
BMC Genomic Data, Vol 25, Iss 1, Pp 1-20 (2024)
Abstract CGGBP1 is a GC-rich DNA-binding protein which is important for genomic integrity, gene expression and epigenome maintenance through regulation of CTCF occupancy and cytosine methylation. It has remained unclear how CGGBP1 integrates multiple
Externí odkaz:
https://doaj.org/article/d800aed12eb943a4bcc6336fc8857cc7
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-14 (2020)
Abstract Background Inhibition of DNA-binding of proteins by small-molecule chemicals holds immense potential in manipulating the activities of DNA-binding proteins. Such a chemical inhibition of DNA-binding of proteins can be used to modulate proces
Externí odkaz:
https://doaj.org/article/a7569ecc62ab481898f4b0e349293fc0
Publikováno v:
BMC Genetics, Vol 21, Iss 1, Pp 1-21 (2020)
Abstract Background The human CGGBP1 binds to GC-rich regions and interspersed repeats, maintains homeostasis of stochastic cytosine methylation and determines DNA-binding of CTCF. Interdependence between regulation of cytosine methylation and CTCF o
Externí odkaz:
https://doaj.org/article/cac7722ca5074cd9aa4add864bb39cd5
Publikováno v:
Epigenetics & Chromatin, Vol 12, Iss 1, Pp 1-22 (2019)
Abstract Background CGGBP1 is a repeat-binding protein with diverse functions in the regulation of gene expression, cytosine methylation, repeat silencing and genomic integrity. CGGBP1 has also been identified as a cooperator of histone-modifying enz
Externí odkaz:
https://doaj.org/article/3f745bf099644182ae5113eeb10de8e4
Publikováno v:
Cancer Informatics, Vol 18 (2019)
Genome-wide occupancy of several histone modifications in various cell types has been studied using chromatin immunoprecipitation (ChIP) sequencing. Histone occupancy depends on DNA sequence features like inter-strand symmetry of base composition and
Externí odkaz:
https://doaj.org/article/921e6ca8ca29484a9e86b1df301407fe
Publikováno v:
Canadian Journal of Biotechnology, Vol 1, Iss Special Issue, Pp 43-43 (2017)
Introduction: Histone modification, a covalent post-translational modification of histone proteins, influences gene expression by altering chromatin structure giving rise to key characteristics to various cell types. While interaction of histone prot
Externí odkaz:
https://doaj.org/article/a7107bd7b85948a9b62110864bb15655
Publikováno v:
Cell Cycle
Binding sites of the chromatin regulator protein CTCF function as important landmarks in the human genome. The recently characterized CTCF-binding sites at LINE-1 repeats depend on another repeat-regulatory protein CGGBP1. These CGGBP1-dependent CTCF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d8c845e4766ad1cb2ddd46104f2f56a
https://doi.org/10.1080/15384101.2021.1982508
https://doi.org/10.1080/15384101.2021.1982508
Autor:
Subhamoy Datta, Manthan Patel, Chakkarai Sathyaseelan, Chandrama Ghosh, Akanksha Mudgal, Divyesh Patel, Thenmalarchelvi Rathinavelan, Umashankar Singh
Our understanding of DNA G-quadruplexes (G4s) fromin vitrostudies has been complemented by genome-wide G4 landscapes from cultured cells. Conventionally, the formation of G4s is accepted to depend on G-repeats such that they form tetrads. However, ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19a55763ba0a8fb7e91450f186b0e674
https://doi.org/10.1101/2022.09.03.506459
https://doi.org/10.1101/2022.09.03.506459
Publikováno v:
Oncotarget
Genomes of somatic cells in culture are prone to spontaneous mutations due to errors in replication and DNA repair. Some of these errors, such as chromosomal fusions, are not rectifiable and subject to selection or elimination in growing cultures. So
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32fac354258cc16850f99ed05ec3dba9
http://hdl.handle.net/10138/352346
http://hdl.handle.net/10138/352346
Genomes of somatic cells in culture are prone to spontaneous mutations due to errors in replication and DNA repair. Some of these errors, such as chromosomal fusions, are not rectifiable and subject to selection or elimination in growing cultures. So
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bfde96224f7325b7e0ce3a96ada5cd0
https://doi.org/10.1101/2021.10.30.466567
https://doi.org/10.1101/2021.10.30.466567