Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Subhamoy Dasgupta"'
Publikováno v:
STAR Protocols, Vol 5, Iss 2, Pp 102993- (2024)
Summary: Photoacoustic imaging (PAI) with co-registered ultrasound (US) is a hybrid non-invasive imaging modality that enables visualization and quantification of tumor hypoxia in live animals. Here, using a breast tumor xenograft model as an example
Externí odkaz:
https://doaj.org/article/a826ddd6a6fd4f84a8fbd5f975c53713
Autor:
Bryan C. Nikolai, Prashi Jain, David L. Cardenas, Brian York, Qin Feng, Neil J. McKenna, Subhamoy Dasgupta, David M. Lonard, Bert W. O’Malley
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract A subset of CD4 + lymphocytes, regulatory T cells (Tregs), are necessary for central tolerance and function as suppressors of autoimmunity against self-antigens. The SRC-3 coactivator is an oncogene in multiple cancers and is capable of pote
Externí odkaz:
https://doaj.org/article/c5aa049a9d6547ecb096ffd0b12d8bba
Autor:
Akash K. Kaushik, Ali Shojaie, Katrin Panzitt, Rajni Sonavane, Harene Venghatakrishnan, Mohan Manikkam, Alexander Zaslavsky, Vasanta Putluri, Vihas T. Vasu, Yiqing Zhang, Ayesha S. Khan, Stacy Lloyd, Adam T. Szafran, Subhamoy Dasgupta, David A. Bader, Fabio Stossi, Hangwen Li, Susmita Samanta, Xuhong Cao, Efrosini Tsouko, Shixia Huang, Daniel E. Frigo, Lawrence Chan, Dean P. Edwards, Benny A. Kaipparettu, Nicholas Mitsiades, Nancy L. Weigel, Michael Mancini, Sean E. McGuire, Rohit Mehra, Michael M. Ittmann, Arul M. Chinnaiyan, Nagireddy Putluri, Ganesh S. Palapattu, George Michailidis, Arun Sreekumar
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
The molecular alterations driving anti-androgen resistance in prostate cancer are unclear. Here, the authors show, using a network-based approach, that inhibition of the hexosamine biosynthetic pathway is necessary to develop resistance and that incr
Externí odkaz:
https://doaj.org/article/928bd0a4d45444ac89e49f796339b9e4
Autor:
Erin Stashi, Rainer B. Lanz, Jianqiang Mao, George Michailidis, Bokai Zhu, Nicole M. Kettner, Nagireddy Putluri, Erin L. Reineke, Lucas C. Reineke, Subhamoy Dasgupta, Adam Dean, Connor R. Stevenson, Natarajan Sivasubramanian, Arun Sreekumar, Francesco DeMayo, Brian York, Loning Fu, Bert W. O’Malley
Publikováno v:
Cell Reports, Vol 6, Iss 4, Pp 633-645 (2014)
Synchrony of the mammalian circadian clock is achieved by complex transcriptional and translational feedback loops centered on the BMAL1:CLOCK heterodimer. Modulation of circadian feedback loops is essential for maintaining rhythmicity, yet the role
Externí odkaz:
https://doaj.org/article/5b7c4512019e45f39a83362dd12a0d3b
Publikováno v:
Cancer Gene Therapy. 30:548-558
Metabolic reprogramming is a hallmark of cancer development, progression, and metastasis. Several metabolic pathways such as glycolysis, tricarboxylic acid (TCA) cycle, lipid metabolism, and glutamine catabolism are frequently altered to support canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e29ecdfd544ede3591d276f2ecb31333
https://doi.org/10.1038/s41417-022-00521-x
https://doi.org/10.1038/s41417-022-00521-x
Publikováno v:
Mol Cancer Ther
Nearly 90% of patients with advanced prostate cancer manifest bone metastases. Distinct from the osteolytic metastasis mostly observed in other cancer types, prostate cancer bone metastasis is typically more osteoblastic, which is relatively understu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::793b45eefb98e7acb4797a2e5d14686a
https://doi.org/10.1158/1535-7163.mct-21-0684
https://doi.org/10.1158/1535-7163.mct-21-0684
Autor:
Ramesh Singh, Huan Meng, Tao Shen, Lance Edward V. Lumahan, Steven Nguyen, Hong Shen, Subhamoy Dasgupta, Li Qin, Dileep Karri, Bokai Zhu, Feng Yang, Cristian Coarfa, Bert W. O’Malley, Ping Yi
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Castration-resistant prostate cancer (CRPC) poses a major clinical challenge with the androgen receptor (AR) remaining to be a critical oncogenic player. Several lines of evidence indicate that AR induces a distinct transcriptional program after andr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74f81bebb86e9732d54b196e079409c3
https://doi.org/10.1073/pnas.2218229120
https://doi.org/10.1073/pnas.2218229120
Supplementary Data from Optimization and Characterization of a Bone Culture Model to Study Prostate Cancer Bone Metastasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21e050cc26d57caccbdd1f56b9808ad1
https://doi.org/10.1158/1535-7163.22523452.v1
https://doi.org/10.1158/1535-7163.22523452.v1
Autor:
Subhamoy Dasgupta, Bert W. O'Malley, Xiang H.-F. Zhang, Kazuaki Takabe, Nagireddy Putluri, Sung Yun Jung, Bokai Zhu, Tao Dai, Eriko Katsuta, Cuijuan Yu, Christian Prechtl, John Hasper, Uan-I Chen, Mayrel Palestino Dominguez, Abhisha Sawant Dessai
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47b7c59a94f8f023746fa031e461add3
https://doi.org/10.1158/0008-5472.22428048.v1
https://doi.org/10.1158/0008-5472.22428048.v1
Autor:
Subhamoy Dasgupta, Bert W. O'Malley, Xiang H.-F. Zhang, Kazuaki Takabe, Nagireddy Putluri, Sung Yun Jung, Bokai Zhu, Tao Dai, Eriko Katsuta, Cuijuan Yu, Christian Prechtl, John Hasper, Uan-I Chen, Mayrel Palestino Dominguez, Abhisha Sawant Dessai
Metabolic dysregulation is a known hallmark of cancer progression, yet the oncogenic signals that promote metabolic adaptations to drive metastatic cancer remain unclear. Here, we show that transcriptional repression of mitochondrial deacetylase sirt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59d9e81c0d7542ba0a3f58ca4d72ad79
https://doi.org/10.1158/0008-5472.c.6512733.v1
https://doi.org/10.1158/0008-5472.c.6512733.v1