Increased Death of Adipose Cells, a Path to Release Cell-Free DNA Into Systemic Circulation of Obese Women

Autor: Subhabrata Basu, Sylvie Hauguel-de Mouzon, Larraine Presley, Maricela Haghiac, Neeta L. Vora, Diana W. Bianchi, Kirby L. Johnson

Publikováno v: Obesity (Silver Spring, Md.)

Remodeling of adipose tissue is required to support the expansion of adipose mass. In obesity, an increased death of adipocytes contributes to the accelerated cellular turnover. We have shown that obesity in pregnancy is associated with metabolic and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6f40f54e4b34594252b75d99c7ed4e7
https://doi.org/10.1038/oby.2012.138

Prolactin and Insulin Ultradian Secretion and Adipose Tissue Lipoprotein lipase Expression in Severely Obese Women After Bariatric Surgery

Autor: Subhabrata Basu, Laura Leccesi, Melania Manco, Geltrude Mingrone, Amerigo Iaconelli, Donatella Gniuli, Menotti Calvani, Roberto Bracaglia, Rachele Berria, Giuseppe Nolfe

Publikováno v: Obesity (Silver Spring, Md.) 16 (2008): 1831–1837. doi:10.1038/oby.2008.297
info:cnr-pdr/source/autori:Mingrone, G 1; Manco, M 2; Iaconelli, A 1; Gniuli, D 1; Bracaglia, R 3; Leccesi, L 1; Calvani, M 1; Nolfe, G 4; Basus, S 5; Berria, R 5/titolo:Prolactin and insulin ultradian secretion and adipose tissue lipoprotein lipase expression in severely obese women after bariatric surgery/doi:10.1038%2Foby.2008.297/rivista:Obesity (Silver Spring, Md.)/anno:2008/pagina_da:1831/pagina_a:1837/intervallo_pagine:1831–1837/volume:16

Background: Hyperprolactinemia is associated with obesity. Furthermore, in human adipose tissue cultured in vitro, prolactin (PRL) inhibited lipoprotein lipase (LPL) activity via functional PRL receptors. Objective: Tostudy PRL and insulin ultradian

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f952cefd8fab0bd4c0d824bbd501068
https://doi.org/10.1038/oby.2008.297

A multifactorial relationship exists between total circulating cell-free DNA levels and maternal BMI

Autor: Patrick M. Catalano, Sylvie Hauguel-de Mouzon, Subhabrata Basu, Diana W. Bianchi, Neeta L. Vora, Kirby L. Johnson

Publikováno v: Prenatal Diagnosis. 32:912-914

Maternal obesity affects 1 in 5 pregnant women in the United States1. Maternal obesity is associated with increased circulating total, but not fetal, cf DNA2. This may be a result of increased production or decreased clearance of cf DNA in obese wome

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::10d1c4a027aaead2c25bb54528371d59
https://doi.org/10.1002/pd.3919

Pregravid obesity associates with increased maternal endotoxemia and metabolic inflammation

Autor: Maricela Haghiac, Jean-Claude Challier, Judi Minium, Patrick M. Catalano, Michele Guerre-Millo, Subhabrata Basu, Larraine Presley, Thaddeus Waters, Katherine Singh, Peter Surace, Sylvie Hauguel-de Mouzon

Publikováno v: Obesity (Silver Spring, Md.). 19(3)

Obese pregnant women develop severe insulin resistance and enhanced systemic and placental inflammation, suggesting associated modifications of endocrine and immune functions. Activation of innate immunity by endotoxins/lipopolysaccharides (LPS) has

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee102879c19f53cc306b9bc877faa1ad
https://pubmed.ncbi.nlm.nih.gov/20930711

High Molecular Mass Multimer Complexes and Vascular Expression Contribute to High Adiponectin in the Fetus

Autor: Halit Pinar, Patrick M. Catalano, S. Hauguel-de Mouzon, Larraine Presley, Laura Laffineuse, K. Hotmire, Subhabrata Basu, Marshall W. Carpenter

High plasma adiponectin concentrations in human fetuses and neonates are unique features of early developmental stages. Yet, the origins of the high adiponectin concentrations in the perinatal period remain elusive.This study was undertaken to identi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f689da4faf9d3cd04b5c13648a8d8e61
https://europepmc.org/articles/PMC2453055/