Effect of DNA repair inhibitor AsiDNA on the incidence of telomere fusion in crisis

Autor: Subecz, Chloé, Sun, Jian-Sheng, Roger, Lauréline

Publikováno v: Human Molecular Genetics
Human Molecular Genetics, 2021, 30 (3-4), pp.172-181. ⟨10.1093/hmg/ddab008⟩
Human Molecular Genetics, Oxford University Press (OUP), 2021, ⟨10.1093/hmg/ddab008⟩

International audience; Abstract Telomere fusions lead to a state of genomic instability, and are thought to drive clonal evolution and tumorigenesis. Telomere fusions occur via both Classical and Alternative Non-Homologous End Joining repair pathway

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ffe11117d072d9169cceaabc72100749
https://hal-mnhn.archives-ouvertes.fr/mnhn-03879689/file/ddab008.pdf

Effect of DNA repair inhibitor AsiDNA on the incidence of telomere fusion in crisis.

Autor: Subecz C; Structure and Instability of Genomes laboratory, 'Muséum National d'Histoire Naturelle' (MNHN), Inserm U1154, CNRS UMR 7196, Paris, France., Sun JS; Structure and Instability of Genomes laboratory, 'Muséum National d'Histoire Naturelle' (MNHN), Inserm U1154, CNRS UMR 7196, Paris, France., Roger L; Structure and Instability of Genomes laboratory, 'Muséum National d'Histoire Naturelle' (MNHN), Inserm U1154, CNRS UMR 7196, Paris, France.

Publikováno v: Human molecular genetics [Hum Mol Genet] 2021 Apr 26; Vol. 30 (3-4), pp. 172-181.