Zobrazeno 1 - 10
of 333
pro vyhledávání: '"Subbarao, Bondada"'
Autor:
Yi Liu, Cuiping Zhang, Zhenyu Li, Chi Wang, Jianhang Jia, Tianyan Gao, Gerhard Hildebrandt, Daohong Zhou, Subbarao Bondada, Peng Ji, Daret St. Clair, Jinze Liu, Changguo Zhan, Hartmut Geiger, Shuxia Wang, Ying Liang
Publikováno v:
Stem Cell Reports, Vol 8, Iss 4, Pp 991-1004 (2017)
Summary: Natural genetic diversity offers an important yet largely untapped resource to decipher the molecular mechanisms regulating hematopoietic stem cell (HSC) function. Latexin (Lxn) is a negative stem cell regulatory gene identified on the basis
Externí odkaz:
https://doaj.org/article/2044fea99ccd4add87594aa956424bd0
Autor:
Chontida Yarana, Hannah Thompson, Luksana Chaiswing, D. Allan Butterfield, Heidi Weiss, Subbarao Bondada, Sara Alhakeem, Suriyan Sukati, Daret K. St. Clair
Publikováno v:
Redox Biology, Vol 26, Iss , Pp - (2019)
Extracellular vesicles (EVs) generated from redox active anticancer drugs are released into the extracellular environment. These EVs contain oxidized molecules and trigger inflammatory responses by macrophages. Using a mouse model of doxorubicin (DOX
Externí odkaz:
https://doaj.org/article/98e908279b00465d8862dbf696cd086c
Autor:
James P. Collard, Mary K. McKenna, Sunil K. Noothi, Sara S. Alhakeem, Jacqueline R. Rivas, Vivek M. Rangnekar, Natarajan Muthusamy, Subbarao Bondada
Publikováno v:
Leukemia & Lymphoma. 63:1810-1822
The chronic lymphocytic leukemia (CLL) microenvironment has been receiving an increasing amount of attention, but there is currently limited data surrounding how the microenvironment affects initial development of CLL. We determined that the spleen i
Autor:
Vivek M. Rangnekar, Brett Spear, Subbarao Bondada, C. Darrell Jennings, Subodh M. Lele, Shirley Qiu, Ravshan Burikhanov, Yanming Zhao
Supplementary Figures 1-3 from Cancer Resistance in Transgenic Mice Expressing the SAC Module of Par-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353e97588a9b1fcebced733392a8390a
https://doi.org/10.1158/0008-5472.22368681.v1
https://doi.org/10.1158/0008-5472.22368681.v1
Autor:
Vivek M. Rangnekar, Brett Spear, Subbarao Bondada, C. Darrell Jennings, Subodh M. Lele, Shirley Qiu, Ravshan Burikhanov, Yanming Zhao
Supplementary Figure Legends 1-3 from Cancer Resistance in Transgenic Mice Expressing the SAC Module of Par-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18d64fd64a0255daf6cb33614ec876af
https://doi.org/10.1158/0008-5472.22368684
https://doi.org/10.1158/0008-5472.22368684
Autor:
Vivek M. Rangnekar, Brett Spear, Subbarao Bondada, C. Darrell Jennings, Subodh M. Lele, Shirley Qiu, Ravshan Burikhanov, Yanming Zhao
Prostate apoptosis response-4 (Par-4) is a tumor-suppressor protein that induces apoptosis in cancer cells, but not in normal/immortalized cells. The cancer-specific proapoptotic action of Par-4 is encoded in its centrally located SAC domain. We repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::398b8e8a0a0bb1de04ec107781352f3d
https://doi.org/10.1158/0008-5472.c.6496068.v1
https://doi.org/10.1158/0008-5472.c.6496068.v1
Autor:
Daret K. St. Clair, Luksana Chaiswing, D. Allan Butterfield, Nicole G Rummel, Subbarao Bondada
Publikováno v:
Cellular and Molecular Life Sciences. 78:6533-6540
Chemotherapy-induced cognitive impairment (CICI) has been observed in a large fraction of cancer survivors. Although many of the chemotherapeutic drugs do not cross the blood-brain barrier, following treatment, the structure and function of the brain
Autor:
Karine Z Oben, Beth W Gachuki, Sara S Alhakeem, Mary K McKenna, Ying Liang, Daret K St Clair, Vivek M Rangnekar, Subbarao Bondada
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169767 (2017)
An understanding of how each individual 5q chromosome critical deleted region (CDR) gene contributes to malignant transformation would foster the development of much needed targeted therapies for the treatment of therapy related myeloid neoplasms (t-
Externí odkaz:
https://doaj.org/article/4bcd361048fb4b30a37263d3c348d29a
Publikováno v:
Antibodies, Vol 3, Iss 1, Pp 116-129 (2014)
B lymphocyte receptors are generated randomly during the bone marrow developmental phase of B cells. Hence, the B cell repertoire consists of both self and foreign antigen specificities necessitating specific tolerance mechanisms to eliminate self-re
Externí odkaz:
https://doaj.org/article/161d49b8c5d24e9ab2fbde89d522c7a7
Autor:
Jon S. Thorson, Sara S. Alhakeem, Gerhard C. Hildebrandt, Subbarao Bondada, Yinan Zhang, Natarajan Muthusamy, Khaled A. Shaaban, Yang Liu, Li Chen, Francesc Marti, James P. Collard, Markos Leggas, Jacqueline R. Rivas, Roger A. Fleischman, Joseph M. Eckenrode
Publikováno v:
Leukemia
T-cell dysfunction is a hallmark of B-cell Chronic Lymphocytic Leukemia (CLL), where CLL cells downregulate T-cell responses through regulatory molecules including programmed death ligand-1 (PD-L1) and Interleukin-10 (IL-10). Immune checkpoint blocka