Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Subba Reddy Katamreddy"'
Publikováno v:
The Journal of Organic Chemistry. 74:3587-3590
A scale-up of diazaindoline 1 was achieved in four stages and 32% overall yield. The key step involved rapid reductive amination of aldehyde 8 with aniline 5 by sodium triacetoxyborohydride (STAB-H) and TFA followed by ring closure of intermediate am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aea68c17e3cff3d3ce3b0d36b33d9b0
https://doi.org/10.1021/jo900157z
https://doi.org/10.1021/jo900157z
Autor:
Dennis Heyer, Lisa A. Orband-Miller, Frank Navas, David W. Gray, Shawn P. Williams, Adwoa Akwabi-Ameyaw, Jean Shearin, Jing Fang, Subba Reddy Katamreddy, Aaron B. Miller, Jonathan E. Britton
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:5075-5077
A series of estrogen receptor ligands based on a 3-alkyl naphthalene scaffold was synthesized using an intramolecular enolate-alkyne cycloaromatization as the key step. Several of these compounds bearing a C6-OH group were shown to be high affinity l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2de6665b6284851455d32b240179f635
https://doi.org/10.1016/j.bmcl.2008.07.121
https://doi.org/10.1016/j.bmcl.2008.07.121
Autor:
Paul R. Johnson, Dallas K. Croom, Sarah R. Bullard, Sean Ross, Ronald L. Brashear, James M. Way, Christopher R. Conlee, Shane M. Hart, Carina Ammala, Vicente Samano, James B. Thompson, Doug Minick, Yun Xu, Dennis Heyer, Shane Roller, Eric E. Boros, Sarva M. Tadepalli, Peckham Gregory, Andrew J. Carpenter, Jennifer A. Kashatus, Subba Reddy Katamreddy, Howard Ray Sauls, Richard Dana Caldwell, Celia P. Briscoe
Publikováno v:
Journal of medicinal chemistry. 55(24)
GPR119 is a 7-transmembrane receptor that is expressed in the enteroendocrine cells in the intestine and in the islets of Langerhans in the pancreas. Indolines and 6,7-dihydro-5H-pyrrolo[2,3-a]pyrimidines were discovered as G protein-coupled receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::042ec05713cf4401600aefc83d2b88d2
https://pubmed.ncbi.nlm.nih.gov/23214471
https://pubmed.ncbi.nlm.nih.gov/23214471
Autor:
Subba Reddy, Katamreddy, Sola, Lluis
Publikováno v:
Journal of Organic Chemistry; 05/28/99, Vol. 64 Issue 11, p3969, 6p, 6 Diagrams, 3 Charts