Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Subazini Thankaswamy Kosalai"'
Autor:
Sagar Mahale, Meenakshi Setia, Bharat Prajapati, Santhilal Subhash, Mukesh Pratap Yadav, Subazini Thankaswamy Kosalai, Ananya Deshpande, Jagannath Kuchlyan, Mirco Di Marco, Fredrik Westerlund, L. Marcus Wilhelmsson, Chandrasekhar Kanduri, Meena Kanduri
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Using fibroblast growth factor 2 (FGF-2) induced sense and antisense transcripts IER3 and IER3-AS1 as a model system, authors highlight the role of HnRNPK in regulating double strand RNA formation in the loci with overlapping transcripts.
Externí odkaz:
https://doaj.org/article/411814645a2a43f093d137eb408eac1f
Autor:
Subazini Thankaswamy Kosalai, Mohammad Hamdy Abdelrazak Morsy, Nikos Papakonstantinou, Larry Mansouri, Niki Stavroyianni, Chandrasekhar Kanduri, Kostas Stamatopoulos, Richard Rosenquist, Meena Kanduri
Publikováno v:
Epigenetics, Vol 14, Iss 11, Pp 1125-1140 (2019)
EZH2 is overexpressed in poor-prognostic chronic lymphocytic leukaemia (CLL) cases, acting as an oncogene; however, thus far, the EZH2 target genes in CLL have not been disclosed. In this study, using ChIP-sequencing, we identified EZH2 and H3K27me3
Externí odkaz:
https://doaj.org/article/d7aaa1095ea44a7b8e065bb6ff41e6ff
Autor:
Mohamad Moustafa Ali, Vijay Suresh Akhade, Subazini Thankaswamy Kosalai, Santhilal Subhash, Luisa Statello, Matthieu Meryet-Figuiere, Jonas Abrahamsson, Tanmoy Mondal, Chandrasekhar Kanduri
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-20 (2018)
Although we know lncRNAs play a role in cancer, the identification of clinically relevant and functional lncRNAs is lacking. Here, the authors identify 633 prognostic markers, 570 S-phase cancer-associated lncRNAs, and show SCAT7 regulates FGF/FGFR a
Externí odkaz:
https://doaj.org/article/157be40b73b2441180be0273025f743a
Autor:
Chandrasekhar Kanduri, Tanmoy Mondal, John Inge Johnsen, Matthias Fischer, Per Kogner, Maite Huarte, Leo Kurian, Ivan Raimondi, Santhilal Subhash, Daniel Jachimowicz, Silke Reischl, Subazini Thankaswamy Kosalai, Prasanna Kumar Juvvuna, Mirco Di Marco, Somsundar Veppil Muralidharan, Sanhita Mitra
Supplementary Text, Supplementary Table Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::008277634027dcc784f8bc3001f50e37
https://doi.org/10.1158/0008-5472.22425708.v1
https://doi.org/10.1158/0008-5472.22425708.v1
Autor:
Chandrasekhar Kanduri, Tanmoy Mondal, John Inge Johnsen, Matthias Fischer, Per Kogner, Maite Huarte, Leo Kurian, Ivan Raimondi, Santhilal Subhash, Daniel Jachimowicz, Silke Reischl, Subazini Thankaswamy Kosalai, Prasanna Kumar Juvvuna, Mirco Di Marco, Somsundar Veppil Muralidharan, Sanhita Mitra
Primers used in the current investigation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c2ea58a04ecaff9b536f62513ff6d74
https://doi.org/10.1158/0008-5472.22425702.v1
https://doi.org/10.1158/0008-5472.22425702.v1
Autor:
Chandrasekhar Kanduri, Tanmoy Mondal, John Inge Johnsen, Matthias Fischer, Per Kogner, Maite Huarte, Leo Kurian, Ivan Raimondi, Santhilal Subhash, Daniel Jachimowicz, Silke Reischl, Subazini Thankaswamy Kosalai, Prasanna Kumar Juvvuna, Mirco Di Marco, Somsundar Veppil Muralidharan, Sanhita Mitra
Neuroblastoma has a low mutation rate for the p53 gene. Alternative ways of p53 inactivation have been proposed in neuroblastoma, such as abnormal cytoplasmic accumulation of wild-type p53. However, mechanisms leading to p53 inactivation via cytoplas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23078e939f7b0d29d05e56d567d1d7b8
https://doi.org/10.1158/0008-5472.c.6512115
https://doi.org/10.1158/0008-5472.c.6512115
Autor:
Mirco Di Marco, Meena Kanduri, Tanmoy Mondal, Subazini Thankaswamy Kosalai, Prasanna Kumar Juvvuna, Chandrasekhar Kanduri
Publikováno v:
Neuro-oncology Advances
Background MYCN has been an attractive therapeutic target in neuroblastoma considering the widespread amplification of the MYCN locus in neuroblastoma, and its established role in neuroblastoma development and progression. Thus, understanding neurobl
Autor:
Silke Reischl, Mirco Di Marco, Catarina Darnfors, Kankadeb Mishra, Mohamad Moustafa Ali, Sagar Mahale, Chandrasekhar Kanduri, Meena Kanduri, Subazini Thankaswamy Kosalai, Luisa Statello, Daniel Jachimowicz
Publikováno v:
Oncogene. 40(13)
Recent advances in genomics unraveled several actionable mutational drivers in lung cancer, leading to promising therapies such as tyrosine kinase inhibitors and immune checkpoint inhibitors. However, the tumors' acquired resistance to the newly-deve
Publikováno v:
Genomics. 109:186-191
Massive data produced due to the advent of next-generation sequencing (NGS) technology is widely used for biological researches and medical diagnosis. The crucial step in NGS analysis is read alignment or mapping which is computationally intensive an
Autor:
Sanhita, Mitra, Somsundar Veppil, Muralidharan, Mirco, Di Marco, Prasanna Kumar, Juvvuna, Subazini Thankaswamy, Kosalai, Silke, Reischl, Daniel, Jachimowicz, Santhilal, Subhash, Ivan, Raimondi, Leo, Kurian, Maite, Huarte, Per, Kogner, Matthias, Fischer, John Inge, Johnsen, Tanmoy, Mondal, Chandrasekhar, Kanduri
Publikováno v:
Cancer research. 81(6)
Neuroblastoma has a low mutation rate for the