The Link between APOE4 Presence and Neuropsychological Test Performance among Mexican Americans and Non-Hispanic Whites of the Multiethnic Health & Aging Brain Study - Health Disparities Cohort

Autor: O'Bryant, Sid E, Barber, Robert C, Philips, Nicole, Johnson, Leigh A, Hall, James R, Subasinghe, Kumudu, Petersen, Melissa, Toga, Arthur W, Yaffe, Kristine, Rissman, Robert A, HABS-HD Study Team

Publikováno v: Dementia and geriatric cognitive disorders, vol 51, iss 1

IntroductionThe APOEε4 allele is the single strongest genetic risk for late-onset Alzheimer's disease (AD). Prior work demonstrates that not only the APOEε4 allele varies by race/ethnicity but also the risk for AD and cognitive impairment conveyed

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Mitochondrial Genome‐Wide Association Study Investigating Indices of Mitochondrial Dysfunction in Mexican Americans Compared to non‐Hispanic Whites.

Autor: Reid, Danielle M, Rowe, Megan, Housini, Mohammad, Subasinghe, Kumudu, Garlotte, Isabelle, Barber, Robert, Jones, Harlan P, Thorpe, Roland J., Sun, Jie, Zhou, Zhengyang, Phillips, Nicole

Publikováno v: Alzheimer's & Dementia: The Journal of the Alzheimer's Association; Dec2023 Supplement 12, Vol. 19, p1-2, 2p

Top Alzheimer's disease risk allele frequencies differ in HABS-HD Mexican- versus Non-Hispanic White Americans.

Autor: Housini M; Department of Pharmacology and Neuroscience School of Biomedical Sciences University of North Texas Health Science Center Fort Worth Texas USA.; Department of Family Medicine & Manipulative Medicine Texas College of Osteopathic Medicine University of North Texas Health Science Center Fort Worth Texas USA., Zhou Z; Department of Biostatistics and Epidemiology School of Public Health University of North Texas Health Science Center Fort Worth Texas USA.; Institute for Translational Research UNT Health Science Center Fort Worth Texas USA., Gutierrez J; Department of Internal Medicine Texas Institute for Graduate Medical Education and Research San Antonio Texas USA., Rao S; Department of Family Medicine & Manipulative Medicine Texas College of Osteopathic Medicine University of North Texas Health Science Center Fort Worth Texas USA., Jomaa R; Department of Family Medicine & Manipulative Medicine Texas College of Osteopathic Medicine University of North Texas Health Science Center Fort Worth Texas USA., Subasinghe K; Department of Microbiology Immunology and Genetics School of Biomedical Sciences University of North Texas Health Science Center Fort Worth Texas USA., Reid DM; Department of Microbiology Immunology and Genetics School of Biomedical Sciences University of North Texas Health Science Center Fort Worth Texas USA., Silzer T; Department of Microbiology Immunology and Genetics School of Biomedical Sciences University of North Texas Health Science Center Fort Worth Texas USA., Phillips N; Institute for Translational Research UNT Health Science Center Fort Worth Texas USA.; Department of Microbiology Immunology and Genetics School of Biomedical Sciences University of North Texas Health Science Center Fort Worth Texas USA., O'Bryant S; Department of Family Medicine & Manipulative Medicine Texas College of Osteopathic Medicine University of North Texas Health Science Center Fort Worth Texas USA.; Institute for Translational Research UNT Health Science Center Fort Worth Texas USA., Barber RC; Department of Family Medicine & Manipulative Medicine Texas College of Osteopathic Medicine University of North Texas Health Science Center Fort Worth Texas USA.; Institute for Translational Research UNT Health Science Center Fort Worth Texas USA.

Publikováno v: Alzheimer's & dementia (Amsterdam, Netherlands) [Alzheimers Dement (Amst)] 2023 Dec 27; Vol. 15 (4), pp. e12518. Date of Electronic Publication: 2023 Dec 27 (Print Publication: 2023).