Zobrazeno 1 - 10
of 1 289
pro vyhledávání: '"Subashchandrabose"'
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract Background Tau protein forms neurofibrillary tangles and becomes deposited in the brain during Alzheimer’s disease (AD). Tau oligomers are the most reactive species, mediating neurotoxic and inflammatory activity. Microglia are the immune
Externí odkaz:
https://doaj.org/article/5e7113b0232544c1be55ebc3008b9742
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-20 (2023)
Abstract Microtubule-associated protein, Tau has been implicated in Alzheimer's disease for its detachment from microtubules and formation of insoluble intracellular aggregates within the neurons. Recent findings have suggested the expulsion of Tau s
Externí odkaz:
https://doaj.org/article/2b8a5adbc3f44348b6161b8bf25ce9fb
Publikováno v:
Medical Journal of Dr. D.Y. Patil Vidyapeeth, Vol 15, Iss 8, Pp 200-209 (2022)
Background: The unprecedented morbidity and mortality associated with COVID-19 pandemic and its unique epidemiological features have contributed to stigmatizing and discriminating attitudes among people. Success of prevention efforts depends on ident
Externí odkaz:
https://doaj.org/article/d3f389e5a2d247e789ed8d2dfa5fd84e
Publikováno v:
Molecular Biomedicine, Vol 2, Iss 1, Pp 1-18 (2021)
Abstract Alzheimer’s disease is a progressive neurodegenerative disease characterized by the presence of amyloid-β plaques in the extracellular environment and aggregates of Tau protein that forms neurofibrillary tangles (NFTs) in neuronal cells.
Externí odkaz:
https://doaj.org/article/9a447cae62094a61ae55574c14430768
Publikováno v:
Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-17 (2021)
Abstract Background Microtubule-associated protein Tau undergoes aggregation in Alzheimer`s disease (AD) and a group of other related diseases collectively known as Tauopathies. In AD, Tau forms aggregates, which are deposited intracellularly as neur
Externí odkaz:
https://doaj.org/article/06366ae7ec744a3ead70368a3ac55062
Publikováno v:
Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-13 (2021)
Abstract Neurodegenerative diseases like Alzheimer’s, Parkinson’s and Huntington’s disease involves abnormal aggregation and accumulation of toxic proteins aggregates. Post-translational modifications (PTMs) of the causative proteins play an im
Externí odkaz:
https://doaj.org/article/6ade5353210c40c7b1e8fc1b69ad8608
Autor:
Nalini V. Gorantla, Lisni P. Sunny, Kolla Rajasekhar, Pramod G. Nagaraju, Poornima Priyadarshini CG, Thimmaiah Govindaraju, Subashchandrabose Chinnathambi
Publikováno v:
ACS Omega, Vol 6, Iss 17, Pp 11131-11138 (2021)
Externí odkaz:
https://doaj.org/article/04798069546649d699af4b3b55e2fa92
Publikováno v:
Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-16 (2021)
Abstract Background Amyloid aggregate deposition is the key feature of Alzheimer’s disease. The proteinaceous aggregates found in the afflicted brain are the intra-neuronal neurofibrillary tangles formed by the microtubule-associated protein Tau an
Externí odkaz:
https://doaj.org/article/b0c1446a5b9842c788d180ef0aeeecbe
Publikováno v:
Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-12 (2021)
Abstract Alzheimer’s disease is one of the neurodegenerative diseases, characterized by the accumulation of abnormal protein deposits, which disrupts signal transduction in neurons and other glia cells. The pathological protein in neurodegenerative
Externí odkaz:
https://doaj.org/article/84a461fa94894b9e99c0cd3f69601270
Publikováno v:
Molecular Biomedicine, Vol 2, Iss 1, Pp 1-14 (2021)
Abstract Alzheimer’s disease (AD) is known by characteristic features, extracellular burden of amyloid-β and intracellular neuronal Tau. Microglia, the innate immune cell of the brain has the ability to clear the burden of accumulated proteins via
Externí odkaz:
https://doaj.org/article/200320c1adc644d7a8ec5eb18482183b