Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Sub IRAS Tox ITX (immunotoxicologie)"'
Autor:
Giustarini, Giulio, Huppelschoten, Suzanna, Barra, Marco, Oppelt, Angela, Wagenaar, Laura, Weaver, Richard J., Bol-Schoenmakers, Marianne, Smit, Joost J., van de Water, Bob, Klingmüller, Ursula, Pieters, Raymond H.H., Sub IRAS Tox ITX (immunotoxicologie), IRAS OH Toxicology, dIRAS RA-1
Publikováno v:
Toxicology and Applied Pharmacology, 391. Academic Press Inc.
Toxicology and Applied Pharmacology, 391, 114915
Toxicology and Applied Pharmacology, 391, 114915
Idiosyncratic drug-induced liver injury (IDILI) is a severe disease that cannot be detected during drug development. It has been shown that hepatotoxicity of some compounds associated with IDILI becomes apparent when these are combined in vivo and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4945db767d654ca81a89a51ddda53492
https://doi.org/10.1016/j.taap.2020.114915
https://doi.org/10.1016/j.taap.2020.114915
Autor:
Van Bilsen, Jolanda H.M., Verschuren, Lars, Wagenaar, Laura, Vonk, Marlotte M., Van Esch, Betty C.A.M., Knippels, Léon M.J., Garssen, Johan, Smit, Joost J., Pieters, Raymond H.H., Van Den Broek, Tim J., Sub IRAS Tox ITX (immunotoxicologie), Afd Pharmacology, One Health Toxicologie, dIRAS RA-1, Pharmacology
Publikováno v:
BMC Bioinformatics, 20(1). NLM (Medline)
BMC Bioinformatics
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-11 (2019)
BMC Bioinformatics
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-11 (2019)
Background Oral immunotherapy (OIT) is a promising therapeutic approach to treat food allergic patients. However, concerns with regards to safety and long-term efficacy of OIT remain. There is a need to identify biomarkers that predict, monitor and/o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7748da00c1ef04c321fe3728618caa12
https://dspace.library.uu.nl/handle/1874/381065
https://dspace.library.uu.nl/handle/1874/381065
Autor:
Wagenaar, Laura, Van Roest, Manon, Kruijssen, Laura J.W., Simons, Peter J., Boon, Louis, Vonk, Marlotte M., Van Esch, Betty C.A.M., Knippels, Leon M.J., Garssen, Johan, Pieters, Raymond H.H., Smit, Joost J., Sub IRAS Tox ITX (immunotoxicologie), One Health Toxicologie, Sub Immunopharmacology, Afd Pharmacology, dIRAS RA-1, Pharmacology
Publikováno v:
Clinical and Molecular Allergy, Vol 17, Iss 1, Pp 1-12 (2019)
Clinical and Molecular Allergy, 17(1). BioMed Central
Clinical and Molecular Allergy : CMA
Clinical and Molecular Allergy, 17(1). BioMed Central
Clinical and Molecular Allergy : CMA
Background Improving the safety of subcutaneous immunotherapy (SCIT) for food allergy is necessary to reduce side effects and achieve long-term tolerance. We determined the effect of dietary supplementation with 1% non-digestible short- and long-chai
Autor:
Wagenaar, Laura, Bol-Schoenmakers, Marianne W.H.C., Giustarini, Giulio, Garssen, Johan, Smit, Joost J., Pieters, Raymond H.H., Sub IRAS Tox ITX (immunotoxicologie), One Health Toxicologie, dIRAS RA-1, Afd Pharmacology, Pharmacology
Publikováno v:
Immunity, Inflammation and Disease
Immunity, inflammation and disease, 7(1), 41. John Wiley and Sons Ltd
Immunity, inflammation and disease, 7(1), 41. John Wiley and Sons Ltd
Background Promising therapies for food allergy are emerging, mostly based on animal experimentation. However, different mouse strains are used, which may make it hard to compare experiments. The current study investigated whether the immunological d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::021712b71bcd29b699fc663a950667e4
https://dspace.library.uu.nl/handle/1874/380138
https://dspace.library.uu.nl/handle/1874/380138
Autor:
Giustarini, Giulio, Vrisekoop, Nienke, Kruijssen, Laura, Wagenaar, Laura, Van Staveren, Selma, Van Roest, Manon, Bleumink, Rob, Bol-Schoenmakers, Marianne, Weaver, Richard J., Koenderman, Leo, Smit, Joost, Pieters, Raymond, Sub IRAS Tox ITX (immunotoxicologie), Sub Immunopharmacology, Sub Center for Cell Imaging, One Health Toxicologie, dIRAS RA-1
Publikováno v:
Toxicological Sciences, 167(2), 385. Oxford University Press
Toxicological sciences : an official journal of the Society of Toxicology, 167(2), 385
Toxicological sciences : an official journal of the Society of Toxicology, 167(2), 385
The fluoroquinolone trovafloxacin (TVX) is associated with a high risk of drug-induced liver injury (DILI). Although part of the liver damage by TVX+TNF relies on neutrophils, we have recently demonstrated that liver recruitment of monocytes and neut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::179ef47f03dbecf4520ebce3afc74890
https://dspace.library.uu.nl/handle/1874/380542
https://dspace.library.uu.nl/handle/1874/380542
Autor:
Wagenaar, Laura, Bol-Schoenmakers, Marianne, Giustarini, Giulio, Vonk, Marlotte M, van Esch, Betty C A M, Knippels, Leon M J, Garssen, Johan, Smit, Joost J, Pieters, Raymond H H, dIRAS RA-1, Sub IRAS Tox ITX (immunotoxicologie), One Health Toxicologie, Afd Pharmacology, Pharmacology
Publikováno v:
Molecular Nutrition & Food Research, 62(20). Wiley-VCH Verlag
Molecular Nutrition & Food Research
Molecular nutrition and food research. Wiley
Molecular nutrition and food research
Molecular Nutrition & Food Research
Molecular nutrition and food research. Wiley
Molecular nutrition and food research
SCOPE: A major downside of oral immunotherapy (OIT) for food allergy is the risk of severe side-effects. Non-digestible short- and long-chain fructo-oligosaccharides (scFOS/lcFOS), reduced allergy development in murine models. We therefor hypothesize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b6e741441a9aef3fb3922a0c8425ae2
https://dspace.library.uu.nl/handle/1874/371946
https://dspace.library.uu.nl/handle/1874/371946
Autor:
Vaessen, Stefan F C, van Lipzig, Marola M H, Pieters, Raymond H H, Krul, Cyrille A M, Wortelboer, Heleen M, van de Steeg, Evita, Sub IRAS Tox ITX (immunotoxicologie), dIRAS RA-1
Publikováno v:
Drug Metabolism and Disposition, 45(4), 353. American Society for Pharmacology and Experimental Therapy
Intestinal transporter proteins and metabolizing enzymes play a crucial role in the oral absorption of a wide variety of drugs. The aim of the current study was to characterize better available intestinal in vitro models by comparing expression level
Autor:
van Bilsen, Jolanda H M, Sienkiewicz-Szłapka, Edyta, Lozano-Ojalvo, Daniel, Willemsen, Linette E. M., Antunes, Celia M, Molina, Elena, Smit, Joost J., Wróblewska, Barbara, Wichers, Harry J., Knol, Edward F., Ladics, Gregory S, Pieters, Raymond H. H., Denery-Papini, Sandra, Vissers, Yvonne M, Bavaro, Simona L, Larré, Colette, Verhoeckx, Kitty C M, Roggen, Erwin L, Afd Pharmacology, Sub IRAS Tox ITX (immunotoxicologie), dIRAS RA-1
Publikováno v:
Clinical and Translational Allergy
Clinical and Translational Allergy, 7(1). BioMed Central
Clinical and Translational Allergy 7 (2017) 1
Clinical and Translational Allergy, BioMed Central, 2017, pp.1-18. ⟨10.1186/s13601-017-0152-0⟩
Clinical and Translational Allergy, 1-18. (2017)
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
Digital.CSIC. Repositorio Institucional del CSIC
instname
Clinical and Translational Allergy, 7(1)
Clinical and Translational Allergy, Vol 7, Iss 1, Pp 1-18 (2017)
Clinical and Translational Allergy, 7(1). BioMed Central
Clinical and Translational Allergy 7 (2017) 1
Clinical and Translational Allergy, BioMed Central, 2017, pp.1-18. ⟨10.1186/s13601-017-0152-0⟩
Clinical and Translational Allergy, 1-18. (2017)
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
Digital.CSIC. Repositorio Institucional del CSIC
instname
Clinical and Translational Allergy, 7(1)
Clinical and Translational Allergy, Vol 7, Iss 1, Pp 1-18 (2017)
[Background] The introduction of whole new foods in a population may lead to sensitization and food allergy. This constitutes a potential public health problem and a challenge to risk assessors and managers as the existing understanding of the pathop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::297d4a4e8aea3a49aac78ef22f052d6b
https://dspace.library.uu.nl/handle/1874/360488
https://dspace.library.uu.nl/handle/1874/360488
Autor:
Vonk, Marlotte M., Wagenaar, Laura, Pieters, Raymond H. H., Knippels, Leon M. J., Willemsen, Linette E. M., Smit, Joost J., van Esch, Betty C. A. M., Garssen, Johan, dIRAS RA-1, Pharmacology, Afd Pharmacology, Sub IRAS Tox ITX (immunotoxicologie)
Publikováno v:
Clinical and Translational Allergy
Clinical and Translational Allergy, 7(1). BioMed Central
Clinical and Translational Allergy, Vol 7, Iss 1, Pp 1-13 (2017)
Clinical and Translational Allergy, 7(35). Biomed Central
Clinical and Translational Allergy, 7(1). BioMed Central
Clinical and Translational Allergy, Vol 7, Iss 1, Pp 1-13 (2017)
Clinical and Translational Allergy, 7(35). Biomed Central
From Pubmed: " BACKGROUND: Antigen-specific immunotherapy (AIT) is a promising therapeutic approach for both cow's milk allergy (CMA) and peanut allergy (PNA), but needs optimization in terms of efficacy and safety. AIM: Compare oral immunotherapy (O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd720bd53f281b84192a3bab2e3707f8
https://dspace.library.uu.nl/handle/1874/380113
https://dspace.library.uu.nl/handle/1874/380113
Autor:
Hammerschmidt-Kamper, Christiane, Biljes, Daniel, Merches, Katja, Steiner, Irina, Daldrup, Thomas, Bol-Schoenmakers, Marianne, Pieters, Raymond H. H., Esser, Charlotte, Sub IRAS Tox ITX (immunotoxicologie), dIRAS RA-1
Publikováno v:
PLoS One, 12(6), 1. Public Library of Science
PLoS ONE
PLoS One
PLoS ONE, Vol 12, Iss 6, p e0180321 (2017)
PLoS ONE
PLoS One
PLoS ONE, Vol 12, Iss 6, p e0180321 (2017)
From PLoS website: In general, dietary antigens are tolerated by the gut associated immune system. Impairment of this so-called oral tolerance is a serious health risk. We have previously shown that activation of the ligand-dependent transcription fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::354b61e0f3daf99ae61a26dedbd719e7
https://dspace.library.uu.nl/handle/1874/359892
https://dspace.library.uu.nl/handle/1874/359892