Novel methods to detect capacitation-related changes in spermatozoa

Autor: Bernecic, Naomi C, Gadella, Bart M, Leahy, Tamara, de Graaf, Simon P, dB&C FR-RMSC FR, dES/dFAH FR, Sub Reproductie mannelijk, Sub Biologie van de mannelijke gameet

Publikováno v: Theriogenology, 137, 56. Elsevier

Prior to interaction with the oocyte, spermatozoa must undergo capacitation, which involves a series of physio-chemical transformations that occur in the female tract. As capacitation is a pre-requisite for successful fertilisation, it is a topic of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d856bab3f74642d93ba56b55222b296a
https://dspace.library.uu.nl/handle/1874/384258

pH-dependent effects of procaine on equine gamete activation

Autor: Leemans, Bart, Stout, Tom A E, Van Soom, Ann, Gadella, Bart M, LS Voortplanting Inwendige Ziekten, dES/dFAH FR, LS Klinische Reproductie, dB&C FR-RMSC FR, Sub Reproductie mannelijk, Sub Biologie van de mannelijke gameet

Publikováno v: BIOLOGY OF REPRODUCTION
Biology of Reproduction, 101(5), 1056. Society for the Study of Reproduction
Biology of Reproduction

Procaine directly triggers pH-dependent cytokinesis in equine oocytes and induces hypermotility in stallion spermatozoa, an important event during capacitation. However, procaine-induced hyperactivated motility is abolished when sperm is washed to re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::772d04a96202f88a80df92be489cd55c
https://biblio.ugent.be/publication/8647416

An oviduct-on-a-chip provides an enhanced in vitro environment for zygote genome reprogramming

Autor: Ferraz, Marcia A M M, Rho, Hoon Suk, Hemerich, Daiane, Henning, Heiko H W, van Tol, Helena T A, Hölker, Michael, Besenfelder, Urban, Mokry, Michal, Vos, Peter L A M, Stout, Tom A E, Le Gac, Séverine, Gadella, Bart M, LS Voortplanting Inwendige Ziekten, dES/dFAH FR, Sub Celbiologisch lab., dFAH AVR, LS Klinische Reproductie, Sub Biologie van de mannelijke gameet, Sub Reproductie mannelijk, dB&C FR-RMSC FR

Publikováno v: Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications, 9(1). Nature Publishing Group
Nature communications, 9:4934. Nature Publishing Group

Worldwide over 5 million children have been conceived using assisted reproductive technology, and research has concentrated on increasing the likelihood of ongoing pregnancy. However, studies using animal models have indicated undesirable effects of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d2541d45c82fec9aa3455a5d459a09e
https://doi.org/10.1038/s41467-018-07119-8

Potential Health and Environmental Risks of Three-Dimensional Engineered Polymers

Autor: de Almeida Monteiro Melo Ferraz, Marcia, Henning, Heiko H W, Ferreira da Costa, Pedro, Malda, Jos, Le Gac, Séverine, Bray, Fabrice, van Duursen, Majorie B M, Brouwers, Jos F, van de Lest, Chris H A, Bertijn, Ingeborg, Kraneburg, Lisa, Vos, Peter L A M, Stout, Tom A E, Gadella, Barend M, One Health Toxicologie, LS Klinische Reproductie, dES/dFAH FR, LS Voortplanting Inwendige Ziekten, Sub Reproductie mannelijk, LS Equine Muscoskeletal Biology, dES RMSC, LS Veterinaire biochemie, Sub MS-faciliteit, dB&C FR-RMSC RMSC, dB&C FR-RMSC FR, dFAH AVR, Sub Biologie van de mannelijke gameet

Publikováno v: Environmental Science & Technology Letters
Environmental Science & Technology Letters, 2018, 5 (2), pp.80-85. ⟨10.1021/acs.estlett.7b00495⟩
Environmental science & technology letters, 5(2), 80-85. American Chemical Society
Environmental Science and Technology Letters, 5(2), 80
Environmental science & technology letters, 5(2), 80. American Chemical Society

Polymer engineering, such as in three-dimensional (3D) printing, is rapidly gaining popularity, not only in the scientific and medical fields but also in the community in general. However, little is known about the toxicity of engineered materials. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::446dd2228c3a905fcbf231811b24183b
https://dspace.library.uu.nl/handle/1874/371939

Binder of Sperm Proteins 1 and 5 have contrasting effects on the capacitation of ram spermatozoa

Autor: Pini, Taylor, de Graaf, Simon P, Druart, Xavier, Tsikis, Guillaume, Labas, Valerie, Teixeira-Gomes, Ana Paula, Gadella, Barend M, Leahy, Tamara, Sub Biologie van de mannelijke gameet, dES/dFAH FR, Sub Reproductie mannelijk, dB&C FR-RMSC FR

Publikováno v: Biology of Reproduction, 98(6), 765. Society for the Study of Reproduction
Biology of Reproduction
Biology of Reproduction, Society for the Study of Reproduction, 2018, 98 (6), pp.765-775. ⟨10.1093/biolre/ioy032⟩

International audience; Binder of Sperm Proteins (BSPs) are the most abundant seminal plasma protein family in the ram and bull. They have been extensively studied in the bull but less is known about their function in ovine seminal plasma and current

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::458ffaaf74a71068686ff45efcfd8b8b
https://pubmed.ncbi.nlm.nih.gov/29415221