Výsledky vyhledávání - "Sub Airway in vivo Pharmacology"

Deficiency or inhibition of lysophosphatidic acid receptor 1 protects against hyperoxia-induced lung injury in neonatal rats

Autor: Chen, Xueyu, Walther, Frans J, van Boxtel, Ruben, Laghmani, El Houari, Sengers, Rozemarijn M A, Folkerts, Gert, DeRuiter, Marco C, Cuppen, Edwin, Wagenaar, Gerry T M, Sub Airway in vivo Pharmacology, Pharmacology

Publikováno v: Acta Physiologica, 216(3), 358-375
Acta Physiologica, 216(3). Wiley-Blackwell
Acta Physiologica, 216(3), 358. Wiley-Blackwell
Acta Physiologica (Oxford, England). Wiley-Blackwell

AIM: Blocking of lysophosphatidic acid (LPA) receptor (LPAR) 1 may be a novel therapeutic option for bronchopulmonary dysplasia (BPD) by preventing the LPAR1-mediated adverse effects of its ligand (LPA), consisting of lung inflammation, pulmonary art

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f71c251ec0e5aa832624473c47b7b2e
https://hdl.handle.net/1887/113950

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The effects of short-chain fatty acids on the cardiovascular system

Autor: Richards, L.B., Li, M., van Esch, B.C.A.M., Garssen, J., Folkerts, G., Sub General Pharmacology, Sub Immunopharmacology, Sub Airway in vivo Pharmacology, Pharmacology

Publikováno v: PharmaNutrition, 4(2), 68. Elsevier Saunders

The development of cardiovascular diseases is often attributable to loss of endothelial functions of the vascular tissue or to decreased contractile function of the heart muscle. These disturbances are often caused by imbalances in lipid and glucose

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d38b8f2756104dc6ffa9598157a15a12
https://dspace.library.uu.nl/handle/1874/336967

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Specific probiotic dietary supplementation leads to different effects during remission and relapse in murine chronic colitis

Autor: Zheng, B, van Bergenhenegouwen, J, van de Kant, H J G, Folkerts, G, Garssen, J, Vos, A P, Morgan, M E, Kraneveld, A D, Sub General Pharmacology, Sub Developmental Biology, Sub Airway in vivo Pharmacology, Sub Immunopharmacology, Pharmacology, Developmental Biology

Publikováno v: Benef Microbes, 7(2), 205. Wageningen Academic Publishers

Although interest in using probiotics to prevent and treat intestinal diseases is increasing, the effects of specific probiotic strains still remain unclear. Here, we assess the therapeutic effects of two probiotic strains, Lactobacillus rhamnosus Nu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e42d0a5fd1c03c16da57d28389b87a0
https://pubmed.ncbi.nlm.nih.gov/26645352

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Regulatory T Cell Depletion Abolishes the Protective Effect of Dietary Galacto-Oligosaccharides on Eosinophilic Airway Inflammation in House Dust Mite-Induced Asthma in Mice

Autor: Verheijden, Kim At, Braber, Saskia, Leusink-Muis, Thea, Thijssen, Suzan, Boon, Louis, Kraneveld, Aletta D, Garssen, Johan, Folkerts, Gert, Willemsen, Linette Em, Sub Immunopharmacology, Sub Airway in vivo Pharmacology, Pharmacology

Publikováno v: Journal of Nutrition, 146(4), 831. American Society for Nutrition

BACKGROUND: In a murine model for house dust mite (HDM)-induced asthma, dietary galacto-oligosaccharides have been shown to suppress allergic symptoms. Previously, CD25(+) regulatory T cells (Tregs) induced by nondigestible oligosaccharides were foun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c92886296aeb35b53a0df88b03919030
https://pubmed.ncbi.nlm.nih.gov/26962188

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The matrikine PGP as a potential biomarker in COPD

Autor: Abdul Roda, Mojtaba, Fernstrand, Amanda M, Redegeld, Frank A, Blalock, J Edwin, Gaggar, Amit, Folkerts, Gert, Pharmacology, Sub General Pharmacology, Sub Airway in vivo Pharmacology, Sub Immunopharmacology

Publikováno v: American journal of physiology. Lung cellular and molecular physiology, 308(11), L1095. American Physiological Society

The lack of a well-characterized biomarker for the diagnosis of chronic obstructive pulmonary disease (COPD) has increased interest toward finding one, because this would provide potential insight into disease pathogenesis and progression. Since pers

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a741df1cb76fecc39e4d599fe8cc7b3
https://europepmc.org/articles/PMC4451398/

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Severity of acute respiratory distress syndrome resulting from tuberculosis correlates with bronchoalveolar lavage CXCL-8 expression

Autor: Adcock, I.M., Hashemian, S.M.R., Mortaz, E., Masjedi, M.R., Folkerts, G., Sub General Pharmacology, Sub Airway in vivo Pharmacology, Pharmacology

Publikováno v: International Journal of Mycobacteriology. Elsevier
International Journal of Mycobacteriology, Vol 4, Iss 5, Pp 71-71 (2015)

Tuberculosis (TB) has previously been linked to acute respiratory distress syndrome (ARDS). Here this study investigates the link between inflammation and TB in ARDS by measuring inflammatory cytokine and chemokine levels in bronchoalveolar lavage (B

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebbf2637746019c1bda94c8a65416abc
https://dspace.library.uu.nl/handle/1874/331004

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Dietary galacto-oligosaccharides prevent airway eosinophilia and hyperresponsiveness in a murine house dust mite-induced asthma model

Autor: Verheijden, Kim A T, Willemsen, Linette E M, Braber, Saskia, Leusink-Muis, Thea, Delsing, Dianne J M, Garssen, Johan, Kraneveld, Aletta D, Folkerts, Gert, Sub Immunopharmacology, LS Pharma, Sub Airway in vivo Pharmacology, Pharmacology

Publikováno v: Respiratory Research, 16. BioMed Central
Respiratory Research

Background Allergic asthma is strongly associated with the exposure to house dust mite (HDM) and is characterized by eosinophilic pulmonary inflammation and airway hyperresponsiveness (AHR). Recently, there is an increased interest in using dietary o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7721e898e17366516b9922b0c2aced40
https://doi.org/10.1186/s12931-015-0171-0

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Inflammation-induced expression of the alarmin interleukin 33 can be suppressed by galacto-oligosaccharides

Autor: Verheijden, Kim A T, Akbari, Peyman, Willemsen, Linette E M, Kraneveld, Aletta D, Folkerts, Gert, Garssen, Johan, Fink-Gremmels, Johanna, Braber, Saskia, Sub Immunopharmacology, Sub Airway in vivo Pharmacology, LS Pharma, Pharmacology

Publikováno v: International Archives of Allergy and Immunology, 167(2), 127. S. Karger AG

Background: The alarmin interleukin 33 (IL-33) and its receptor ST2 play an important role in mucosal barrier tissues, and seem to be crucial for Th2-cell mediated host defense. Galacto-oligosaccharides (GOS), used in infant formulas, exhibit gut and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb69b98ed8ec823189f98d5012cbc7fb
https://dspace.library.uu.nl/handle/1874/329589

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Nasal IL-17F is related to bronchial IL-17F/neutrophilia and exacerbations in stable atopic severe asthma

Autor: Sorbello, V, Ciprandi, G, Di Stefano, A, Massaglia, G M, Favatà, G, Conticello, S, Malerba, M, Folkerts, G, Profita, M, Rolla, G, Ricciardolo, F L M, Sub Airway in vivo Pharmacology, Pharmacology

Publikováno v: Allergy, 70(2), 236. Blackwell Publishing Ltd

Severe asthma (SA) is associated with neutrophil recruitment and T helper (TH )17 chemokine overexpression in bronchial biopsies. We aimed to evaluate IL-17A and IL-17F expression in nasal/bronchial lamina propria of atopic mild-to-severe asthmatics

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7febcdc943cd023c3c8095e31b375707
http://hdl.handle.net/2318/1508812

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Anti-Inflammatory Effects of Lactobacillus Rahmnosus and Bifidobacterium Breve on Cigarette Smoke Activated Human Macrophages

Autor: Mortaz, Esmaeil, Adcock, Ian M, Ricciardolo, Fabio L M, Varahram, Mohammad, Jamaati, Hamidreza, Velayati, Ali Akbar, Folkerts, Gert, Garssen, Johan, Sub Airway in vivo Pharmacology, Sub Immunopharmacology, Pharmacology

Publikováno v: PLoS ONE
PLoS One, 10(8). Public Library of Science
PLoS ONE, Vol 10, Iss 8, p e0136455 (2015)

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a major global health problem with cigarette smoke (CS) as the main risk factor for its development. Airway inflammation in COPD involves the increased expression of inflammatory mediators s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceb0ea73dac4ec13e43586086cbf646f
https://hdl.handle.net/1874/325186

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