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pro vyhledávání: '"Suan Liang Kelvin Tan"'
Autor:
Rengaraj Anantharaj, Ravi Kambadur, Peng Zhao Feng, Sabeera Bonala, Sushmitha Sathiyamoorthy, Sudarsanareddy Lokireddy, Arigela Harikumar, Craig McFarlane, Suan Liang Kelvin Tan, Mridula Sharma, Kottaiswamy Amuthavalli, Himani Kukreti, Sandhya Sriram
Publikováno v:
The Journal of biological chemistry. 288(9)
High doses of dexamethasone (Dex) or myostatin (Mstn) induce severe atrophy of skeletal muscle. Here we show a novel microRNA1 (miR1)-mediated mechanism through which Dex promotes skeletal muscle atrophy. Using both C2C12 myotubes and mouse models of