Estrogen signalling and the metabolic syndrome: targeting the hepatic estrogen receptor alpha action.

Autor: Marko Matic, Galyna Bryzgalova, Hui Gao, Per Antonson, Patricia Humire, Yoko Omoto, Neil Portwood, Camilla Pramfalk, Suad Efendic, Per-Olof Berggren, Jan-Åke Gustafsson, Karin Dahlman-Wright

Publikováno v: PLoS ONE, Vol 8, Iss 2, p e57458 (2013)

An increasing body of evidence now links estrogenic signalling with the metabolic syndrome (MS). Despite the beneficial estrogenic effects in reversing some of the MS symptoms, the underlying mechanisms remain largely undiscovered. We have previously

Externí odkaz: https://doaj.org/article/78c9ceb9069a42e8ae141228c6a11656

Correction: Excessive Islet NO Generation in Type 2 Diabetic GK Rats Coincides with Abnormal Hormone Secretion and Is Counteracted by GLP-1.

Autor: Albert Salehi, Sandra Meidute Abaraviciene, Javier Jimenez-Feltstrom, Claes-Göran Östenson, Suad Efendic, Ingmar Lundquist

Publikováno v: PLoS ONE, Vol 3, Iss 6 (2008)

Externí odkaz: https://doaj.org/article/603b701743b440aca56989767c397ab4

Analyses of IGFBP2 DNA methylation and mRNA expression in visceral and subcutaneous adipose tissues of obese subjects

Autor: Kerstin Brismar, Jan Frystyk, Harvest F. Gu, Xiuli Zhang, Anders Thorell, Suad Efendic

Publikováno v: Zhang, X, Gu, H F, Frystyk, J, Efendic, S, Brismar, K & Thorell, A 2019, ' Analyses of IGFBP2 DNA methylation and mRNA expression in visceral and subcutaneous adipose tissues of obese subjects ', Growth Hormone & I G F Research, vol. 45, pp. 31-36 . https://doi.org/10.1016/j.ghir.2019.03.002
Zhang, X, Gu, H F, Frystyk, J, Efendic, S, Brismar, K & Thorell, A 2019, ' Analyses of IGFBP2 DNA methylation and mRNA expression in visceral and subcutaneous adipose tissues of obese subjects ', Growth Hormone and IGF Research, vol. 45, pp. 31-36 . https://doi.org/10.1016/j.ghir.2019.03.002

Insulin-like growth factor binding-protein 2 (IGFBP-2) is secreted by differentiating white adipocytes. Clinical studies demonstrate that circulating IGFBP-2 levels associated inversely with body mass index (BMI) and insulin resistance. To explore po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d62b2dfa510790c8f1c3192887d2cbe3
https://pure.au.dk/portal/da/publications/analyses-of-igfbp2-dna-methylation-and-mrna-expression-in-visceral-and-subcutaneous-adipose-tissues-of-obese-subjects(8f337610-d2c2-4e39-954c-76870f488990).html

17β-Estradiol suppresses visceral adipogenesis and activates brown adipose tissue-specific gene expression

Autor: Saad Misfer Al-Qahtani, Marion Korach-André, Galyna Bryzgalova, Per Olof Berggren, Karin Dahlman-Wright, Neil Portwood, Suad Efendic, Ismael Valladolid-Acebes

Publikováno v: Hormone Molecular Biology and Clinical Investigation. 29:13-26

Both functional ovaries and estrogen replacement therapy (ERT) reduce the risk of type 2 diabetes (T2D). Understanding the mechanisms underlying the antidiabetic effects of 17β-estradiol (E2) may permit the development of a molecular targeting strat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9039c0abf1aa44aeba2325ac02074aa
https://doi.org/10.1515/hmbci-2016-0031

Perioperative insulin and glucose infusion maintains normal insulin sensitivity after surgery

Autor: Anders Thorell, Fredrik Karpe, Suad Efendic, Kerstin Brismar, K. S. Nair, Jonas Nygren, Olle Ljungqvist, Mattias Soop

Publikováno v: Europe PubMed Central
Scopus-Elsevier
Karolinska Institutet

Elective surgery was performed after overnight fasting, a routine that may affect the metabolic response to surgery. We investigated the effects of insulin and glucose infusions before and during surgery on postoperative substrate utilization and ins

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63e2144a093866ea74206d3a6948283f
https://ora.ox.ac.uk/objects/uuid:7351e522-e2c2-490d-b081-09037578abf6