Zobrazeno 1 - 10
of 127
pro vyhledávání: '"SuXia Geng"'
Autor:
Chao Li, Maozhi Xiao, Suxia Geng, Yulian Wang, Lingji Zeng, Peilong Lai, Ying Gong, Xiaomei Chen
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionExploring monocytes’ roles within the tumor microenvironment is crucial for crafting targeted cancer treatments.MethodsThis study unveils a novel methodology utilizing four 20-color flow cytometry panels for comprehensive peripheral imm
Externí odkaz:
https://doaj.org/article/619d03afec874c2da889396cae455022
Autor:
Chao Li, ChengXin Deng, Ping Wu, KaiFan Liu, Xin Huang, MingMin Li, XiaoMei Chen, SuXia Geng, PeiLong Lai, JianYu Weng, Xin Du
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 1, Pp n/a-n/a (2024)
Abstract Chronic myelomonocytic leukemia (CMML) treatment remains a pressing clinical challenge. We conducted a retrospective analysis on 52 CMML cases, exploring the effectiveness of combining venetoclax (Vene) with hypomethylating agents (HMAs). Th
Externí odkaz:
https://doaj.org/article/438382a7e4c54e7a90df59af1f69a39b
Autor:
Xiaomei Chen, Chao Li, Yulian Wang, Suxia Geng, Maozhi Xiao, Lingji Zeng, Chengxin Deng, Minming Li, Xin Huang, Jianyu Weng, Xin Du, Peilong Lai
Publikováno v:
Hematology, Vol 28, Iss 1 (2023)
ABSTRACTThis study delves into the emerging role of ferroptosis in Myelodysplastic Neoplasms (MDS) and aims to identify a prognostic ferroptosis-related gene signature for MDS. Utilizing RNA-seq data and clinical information from the Gene Expression
Externí odkaz:
https://doaj.org/article/ce27c683265f4a74a24ebf72ffb89c5f
Autor:
Ruohao Xu, Miao Wu, Yawen Wang, Chao Li, Lingji Zeng, Yulian Wang, Maozhi Xiao, Xiaomei Chen, Suxia Geng, Peilong Lai, Xin Du, Jianyu Weng
Publikováno v:
Molecular Medicine, Vol 29, Iss 1, Pp 1-15 (2023)
Abstract Background Myofibroblasts (MFB), one of the major effectors of pathologic fibrosis, mainly derived from the activation of fibroblast to myofibroblast transition (FMT). Although MFBs were historically considered terminally differentiated cell
Externí odkaz:
https://doaj.org/article/8979a0f83a9b49db8b0e55c7d540f09f
Autor:
Peilong Lai, Xiaomei Chen, Yulian Wang, Jinghua Wang, Yuchen Zhang, Suxia Geng, Peng Li, Xin Du, Jianyu Weng, Duanqing Pei
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-5 (2022)
Abstract Although chimeric antigen receptor (CAR)-modified adoptive T cell therapy is a promising immunotherapy for hematological malignancies, the efficacy improvement in relapsed/refractory acute lymphoblastic leukemia (ALL) with extramedullary inf
Externí odkaz:
https://doaj.org/article/e5b6465173e74e7591d55ce63cb533b0
Autor:
Lenghe Zhang, Lijuan Zhou, Yulian Wang, Chao Li, Pengjun Liao, Liye Zhong, Suxia Geng, Peilong Lai, Xin Du, Jianyu Weng
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Identifying subgroups of T-cell acute lymphoblastic leukemia (T-ALL) with poor survival will significantly influence patient treatment options and improve patient survival expectations. Current efforts to predict T-ALL survival expectations in multip
Externí odkaz:
https://doaj.org/article/f31fa1d91425449b89aeed35a32bb731
Autor:
Yulian Wang, Lisi Huang, Tian Huang, Suxia Geng, Xiaomei Chen, Xin Huang, Peilong Lai, Xin Du, Jianyu Weng
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
IntroductionDysbiosis of gut bacteria has been discovered in a large number of autoimmune diseases. However, the influence of the gut bacteria in the mice model of chronic sclerodermatous graft-versus-host disease (Scl-GVHD), a disease that resembles
Externí odkaz:
https://doaj.org/article/444f60f005cb48d6b087e25a572112f1
Autor:
Xin Huang, Cunte Chen, Mengjun Zhong, Suxia Geng, Yujie Zhao, Minming Li, Chenxin Deng, Lingji Zeng, Ping Wu, Zesheng Lu, Jianyu Weng, Xin Du, Yangqiu Li
Publikováno v:
Biomarker Research, Vol 9, Iss 1, Pp 1-5 (2021)
Abstract Myelodysplastic syndrome (MDS) is an aggressive and genetically heterogeneous disease with poor prognosis. Cellular immune disorder is a common characteristic of this disease and is thought to be related to clinical outcome. Alterations in T
Externí odkaz:
https://doaj.org/article/fe401c4529e047ea846b89e606435bc8
Autor:
Suxia Geng, Ruohao Xu, Xin Huang, Minming Li, Chengxin Deng, Peilong Lai, Yulian Wang, Ping Wu, Xiaomei Chen, Jianyu Weng, Xin Du
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Hypomethylating agents (HMAs) are widely used in patients with higher-risk MDS not eligible for stem cell transplantation. However, the general response rate by HMAs is lesser than 50% in MDS patients, while the relapse rate is high. Emerging evidenc
Externí odkaz:
https://doaj.org/article/c4f90879820d4bb0a080d4069b6b6fc0
Autor:
Jinghua Wang, Zewei Zhuo, Yanjun Wang, Shuo Yang, Jierong Chen, Yulian Wang, Suxia Geng, Minming Li, Xin Du, Peilong Lai, Jianyu Weng
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
Background: Emerging evidence has proven that ferroptosis plays an important role in the development of acute myeloid leukemia (AML), whereas the exact role of ferroptosis-associated genes in AML patients’ prognosis remained unclear.Materials and M
Externí odkaz:
https://doaj.org/article/7945e019d3594e0f8d3f55b428d3e459