Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Su-Sen Chang"'
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50087 (2012)
Uroporphyrinogen decarboxylase (UROD) has been suggested as a protectant against radiation for head and neck cancer (HNC). In this study, we employed traditional Chinese medicine (TCM) compounds from TCM Database@Taiwan (http://tcm.cmu.edu.tw/) to sc
Externí odkaz:
https://doaj.org/article/4645967677c04c22bc4af8b920d1b2cd
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e43932 (2012)
Pancreatic triacylglycerol lipase (PNLIP) are primary lipases that are critical for triacylglyceride digestion in human. Since reduced metabolism of triacylglyceride might be a plausible concept for weight loss, we screened for potential PNLIP inhibi
Externí odkaz:
https://doaj.org/article/8748272078664e70880a1843b230b2f1
Two birds with one stone? Possible dual-targeting H1N1 inhibitors from traditional Chinese medicine.
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 12, p e1002315 (2011)
The H1N1 influenza pandemic of 2009 has claimed over 18,000 lives. During this pandemic, development of drug resistance further complicated efforts to control and treat the widespread illness. This research utilizes traditional Chinese medicine Datab
Externí odkaz:
https://doaj.org/article/69b24b1bbaae425ba4198f088ef7dfc2
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 10, p e1002189 (2011)
Overexpression of epidermal growth factor receptor (EGFR) has been associated with cancer. Targeted inhibition of the EGFR pathway has been shown to limit proliferation of cancerous cells. Hence, we employed Traditional Chinese Medicine Database (TCM
Externí odkaz:
https://doaj.org/article/07c44bc0af3b42e298e5de4b4b9e1426
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28793 (2011)
The relationship between abnormal HER2 expression and cancer is important in cancer therapeutics. Formation and spread of cancer cells may be restricted by inhibiting HER2. We conducted ligand-based and structure-based studies to assess the potency o
Externí odkaz:
https://doaj.org/article/226c4459e3c6464c92e3ed0faa429739
Publikováno v:
Journal of Food Protection. 78:831-835
Alicyclobacillus spp. is of significance to the fruit juice industry due to the production of guaiacol. Studies on Alicyclobacillus regarding guaiacol focus mainly on novel ways to detect guaiacol or evaluate guaiacol-producing potential of isolated
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 31:1358-1369
Overexpression of epidermal growth factor receptor (EGFR), Her2, and uroporphyrinogen decarboxylase (UROD) occurs in a variety of malignant tumor tissues. UROD has potential to modulate tumor response of radiotherapy for head and neck cancer, and EGF
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 31:1411-1439
Cognitive repair by insulin-like growth factor-I (IGF-I) through activation of insulin-like growth factor-I receptor (IGF-IR) is well established, but not used for clinical therapy due to its link to cancer. We hypothesize that IGF-IR activation rath
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 31:1219-1235
Insulin-degrading enzyme (IDE) gene is one of the type 2 diabetes mellitus susceptibility genes specific to the Han Chinese population. IDE, a zinc-metalloendopeptidase, is a potential target for controlling insulin degradation. Potential lead compou
Publikováno v:
International Journal of Food Microbiology. 164:1-6
The purpose of this study is to develop a selective and differential medium (SK2 agar) for isolating guaiacol producing Alicyclobacillus. Forty-one selected dyes and vanillic acid were incorporated in SK agar for screening selective and differential