Differential genotoxicity of Polygoni Multiflori in rat and human: insights from Ames test and S9 metabolic activation system

Autor: Su-Min Bak, Seng-Min Back, Da Yeon Kim, Soyoung Jung, Na-Young Jeung, Nan-Young Kim, Kang-Hyun Han, Yong-Bum Kim, Byoung-Seok Lee, Jun Hong Park, Hee Jun Cho, Hee Gu Lee, Ozkan Ozden, Sang Kyum Kim, Seong-Hoon Park

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)

Abstract The Ames test is used worldwide to initially screen the mutagenic potential of new chemicals. In the standard Ames test, S. typhimurium strains (TA100, TA98, TA1535, and TA1537) and Escherichia coli (WP2uvrA) are treated with substances with

Externí odkaz: https://doaj.org/article/85b4f4bb8d8141bdab1372c82fdfd13a

Genotoxicity assessment of root extracts of Paeonia lactiflora Pall

Autor: Su-Min Bak, Seng-Min Back, Da Yeon Kim, Na-Young Jeung, Nan-Young Kim, Jun-Young Yang, Kang-Hyun Han, Yong-Bum Kim, Byung Sun Min, Byoung-Seok Lee, Seong-Hoon Park

Publikováno v: Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 886:503579

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3b66ba538de00c7dec625daa7351c68e
https://doi.org/10.1016/j.mrgentox.2022.503579

Tetracycline Resistance Gene Profiles in Red Seabream (Pagrus major) Intestine and Rearing Water After Oxytetracycline Administration

Autor: Satoru Suzuki, Kazuki Kanda, Hisato Iwata, Su-Min Bak, Naoto Kataoka, Yumiko Obayashi, Aya Kadoya

Publikováno v: Frontiers in Microbiology
Frontiers in Microbiology, Vol 11 (2020)

Marine aquaculture fish and the environment are possible hot spots for the maintenance and spread of antibiotic resistance genes (ARGs). We here show the time courses of changes of six tetracycline resistance genes (tet) in fish rearing seawater and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::980e3097b902c14c71a0fbcffe893e7f
http://europepmc.org/articles/PMC7417432

Auto-induction mechanism of aryl hydrocarbon receptor 2 (AHR2) gene by TCDD-activated AHR1 and AHR2 in the red seabream (Pagrus major)

Autor: Midori Iida, Su Min Bak, Michael S. Denison, Anatoly A. Soshilov, Eun-Young Kim, Hisato Iwata

Publikováno v: Archives of toxicology, vol 91, iss 1
Bak, SM; Iida, M; Soshilov, AA; Denison, MS; Iwata, H; & Kim, EY. (2017). Auto-induction mechanism of aryl hydrocarbon receptor 2 (AHR2) gene by TCDD-activated AHR1 and AHR2 in the red seabream (Pagrus major). Archives of Toxicology, 91(1), 301-312. doi: 10.1007/s00204-016-1732-9. UC Office of the President: Research Grants Program Office (RGPO). Retrieved from: http://www.escholarship.org/uc/item/3vx1k9h3

© 2016, Springer-Verlag Berlin Heidelberg. The toxic effects of dioxins and related compounds (DRCs) are mediated by the aryl hydrocarbon receptor (AHR). Our previous study identified AHR1 and AHR2 genes from the red seabream (Pagrus major). Moreove

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::601c578ca2f51c0ffa464378a7440338
https://doi.org/10.1007/s00204-016-1732-9

Potencies of Red Seabream AHR1- and AHR2-Mediated Transactivation by Dioxins: Implication of Both AHRs in Dioxin Toxicity

Autor: Midori Iida, Su-Min Bak, Eun-Young Kim, Hisato Iwata, Masashi Hirano

Publikováno v: Environmental Science & Technology. 47:2877-2885

To evaluate species- and isoform-specific responses to dioxins and related compounds (DRCs) via aryl hydrocarbon receptor (AHR) in the red seabream ( Pagrus major ), we constructed a reporter gene assay system. Each expression plasmid of red seabream

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d284aaee1454900ab045a3f91d14f5b
https://doi.org/10.1021/es304423w