Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Su-Li Cheng"'
Autor:
Bindu Ramachandran, Parastoo Sabaeifard, Andrew Lemoff, Mohammad Goodarzi, Megan Mead, Li L. Li, Henry M. Kronenberg, Dalian Zhong, Su Li Cheng, Dwight A. Towler, Abraham Behrmann
Publikováno v:
Circ Res
Rationale: The PTH1R (PTH [parathyroid hormone]/PTHrP [PTH-related protein] receptor) is expressed in vascular smooth muscle (VSM) and increased VSM PTH1R signaling mitigates diet-induced arteriosclerosis in LDLR −/− mice. Objective: To study the
Autor:
Bindu Ramachandran, John N. Stabley, Su-Li Cheng, Abraham S. Behrmann, Austin Gay, Li Li, Megan Mead, Julia Kozlitina, Andrew Lemoff, Hamid Mirzaei, Zhijian Chen, Dwight A. Towler
Publikováno v:
Journal of Biological Chemistry. 293:7942-7968
In aortic vascular smooth muscle (VSM), the canonical Wnt receptor LRP6 inhibits protein arginine (Arg) methylation, a new component of noncanonical Wnt signaling that stimulates nuclear factor of activated T cells (viz. NFATc4). To better understand
Autor:
Jia-Chun Xu, Zhi-Heng Zhao, Su-Li Cheng, Xue Wang, Zhao-Hua Jiao, Zhi-Min Cai, Zhen Zhou, Bao-Hong Liu, Yan Li
Publikováno v:
Traditional Medicine Research, Vol 2, Iss 3, Pp 149-154 (2017)
Objective: To explore the effect of fire needle on the expression of ERK1/2 of neural stem cells (NSCs) obtained from rats with spinal cord injury (SCI). Methods: Sixty SD female rats were randomly divided into 5 groups, including 5 in the blank grou
Autor:
Karen Krchma, Kapil Kapoor, Jian Su Shao, Dwight A. Towler, Bart O. Williams, Abraham Behrmann, Ranjan J. Perera, Carolyn Smith, Attila Kovacs, Su Li Cheng, Megan Mead, Yoanna Bello Arredondo, Bindu Ramachandran, Laurence M. Brill
Publikováno v:
Circulation Research. 117:142-156
Rationale: Wnt signaling regulates key aspects of diabetic vascular disease. Objective: We generated SM22-Cre;LRP6(fl/fl);LDLR −/− mice to determine contributions of Wnt coreceptor low-density lipoprotein receptor–related protein 6 (LRP6) in th
Publikováno v:
World Journal of Acupuncture - Moxibustion. 25:35-43
Dr. He's bloodletting therapy utilizing three edged needles is one of his “three adjusting methods of acupuncture”. During his 70 years of clinical practice, he developed the theory that most diseases are caused by qi stagnation, and in order to
Autor:
Megan Mead, Bindu Ramachandran, Karen Krchma, Jian Su Shao, Yoanna Bello Arredondo, Robert E. Maxson, Dwight A. Towler, Su Li Cheng, Attila Kovacs, Abraham Behrmann
Publikováno v:
Diabetes. 63:4326-4337
When fed high-fat diets, male LDLR−/− mice develop obesity, hyperlipidemia, hyperglycemia, and arteriosclerotic calcification. An osteogenic Msx-Wnt regulatory program is concomitantly upregulated in the vasculature. To better understand the mech
Autor:
Austin T Gay, Bindu Ramachandran, John N Stabley, Su-Li Cheng, Abraham Behrmann, Li Li, Megan Mead, Bart O Williams, Zhijian Chen, Dwight A Towler
Publikováno v:
Circulation Research. 121
In vascular smooth muscle (VSM), LRP6, a Wnt co-receptor, inhibits arteriosclerotic noncanonical Wnt signals that activate protein arginine (Arg) methylation relays, converging on nuclear factor of activated T cells (NFAT). LRP6 deletion in VSM incre
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 33:1679-1689
Objective— Endothelial cells (ECs) can undergo an endothelial–mesenchymal transition with tissue fibrosis. Wnt- and Msx2-regulated signals participate in arteriosclerotic fibrosis and calcification. We studied the impact of Wnt7, Msx2, and Dkk1,
Autor:
Bindu Ramachandran, Dwight A. Towler, Su-Li Cheng, Kapil Kapoor, Megan Mead, Abraham Behrmann, Henry M. Kronenberg, Ranjan J. Perera
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 36
When fed a high fat diet, male LDL receptor -deficient (LDLR-/-) mice develop type 2 diabetes (T2D) with concomitant arteriosclerosis. The PTH receptor (PTH1R) is highly expressed in the vasculature. To better understand the role of PTH1R signaling i
Autor:
Jeffrey G. McDonald, Abraham Behrmann, John N. Stabley, Su-Li Cheng, Megan Mead, Bart O. Williams, Bindu Ramachandran, Dwight A. Towler
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 36
When fed a high fat diet (HFD) typical of westernized societies, male LDL receptor -deficient (LDLR-/-) mice develop obesity and insulin-resistant diabetes, with concomitant arteriosclerotic calcification and fibrosis. We recently demonstrated that n