Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Su-Ji Min"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
Calsenilin (CSEN) binds to Kv4.2 (an A-type K+ channel) as well as N-methyl-D-aspartate receptor (NMDAR), and modulates their activities. However, the regulatory mechanisms for CSEN-binding to Kv4.2 or NMDAR remain elusive. Here, we demonstrate the n
Externí odkaz:
https://doaj.org/article/4893c4b7aaee4cffa59d42a4bab2d831
Publikováno v:
Polymers, Vol 16, Iss 2, p 231 (2024)
This study evaluated the ameliorative effects of Korean-red-ginseng-derived polysaccharide (KRG-P) on antibiotic-associated diarrhea (AAD) induced by administering lincomycin in mice. Changes of intestinal barrier proteins, the intestinal microbiome
Externí odkaz:
https://doaj.org/article/a53e9e44aa7746fb9b272f932c668b63
Publikováno v:
Molecules, Vol 28, Iss 18, p 6743 (2023)
Ten traditional herbal extracts effective against diarrhea, infectious diseases, and bacterial activity were selected and analyzed for Peyer’s patch cell-mediated intestinal immunomodulatory activity in vitro and in vivo. Among the 10 herbal extrac
Externí odkaz:
https://doaj.org/article/d20157ab602444e6ae72fcd582fd47a2
Synthesis and Biological Properties of Pyranocoumarin Derivatives as Potent Anti-Inflammatory Agents
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 10026 (2023)
This study aimed to synthesize 23 coumarin derivatives and analyze their anti-inflammatory effects on lipopolysaccharide (LPS)-induced inflammation in RAW264.7 macrophages. A cytotoxicity test performed on LPS-induced RAW264.7 macrophages revealed th
Externí odkaz:
https://doaj.org/article/7a3bb37b14824e5e805f746a1fdd1775
Synthesis and Biological Properties of Pyranocoumarin Derivatives as Potent Anti-Inflammatory Agents
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 12; Pages: 10026
This study aimed to synthesize 23 coumarin derivatives and analyze their anti-inflammatory effects on lipopolysaccharide (LPS)-induced inflammation in RAW264.7 macrophages. A cytotoxicity test performed on LPS-induced RAW264.7 macrophages revealed th
Publikováno v:
Brain Research. 1670:14-23
Leptomycin B (LMB), originally developed as an anti-fungal agent, has potent neuroprotective properties against status epilepticus (SE, a prolonged seizure activity). However, the pharmacological profiles and mechanisms of LMB for neuroprotection rem
Publikováno v:
Neuroscience Research. 119:24-37
Status epilepticus (SE) results in the unique pattern of dynamin-related protein 1 (DRP1)-mediated mitochondrial dynamics, which is associated with astroglial apoptosis and reactive astrogliosis in the regional-specific pattern representing the diffe
Publikováno v:
Brain Research. 1651:27-35
The blood-brain barrier (BBB) disruption during brain insults leads to vasogenic edema as one of the primary steps in the epileptogenic process. However, the signaling pathway concerning vasogenic edema formation has not been clarified. In the presen
Autor:
Tae-Cheon Kang, Su-Ji Min
Publikováno v:
Neuroscience. 337:37-47
Brain-blood barrier (BBB) disruption results in vasogenic edema, which is involved in the pathogenesis of epilepsy. Following status epilepticus (SE), up-regulated transient receptor potential canonical channel-3 (TRPC3), a Ca2+-permeable cation chan
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 9, Iss 5, Pp 1-16 (2018)
Cell Death and Disease, Vol 9, Iss 5, Pp 1-16 (2018)
Recently, we have reported that heat shock protein B1 (HSPB1) and purinergic receptor P2X7 (P2RX7) are involved in astroglial autophagy (clasmatodendrosis), following status epilepticus (SE). However, the underlying mechanisms of astroglial autophagy