Zobrazeno 1 - 10
of 669
pro vyhledávání: '"Su Zeng"'
Autor:
Minghe Lv, Yue feng, Su Zeng, Yang Zhang, Wenhao Shen, Wenhui Guan, Xiangyu E., Hongwei Zeng, Ruping Zhao, Jingping Yu
Publikováno v:
Radiation Oncology, Vol 19, Iss 1, Pp 1-13 (2024)
Abstract Background Recent research has demonstrated that the use of artificial intelligence (AI) in radiotherapy (RT) has significantly streamlined the process for physicians to treat patients with tumors; however, bibliometric studies examining the
Externí odkaz:
https://doaj.org/article/3d2dea9c5d564cad8c93d19dc17e2a7b
Autor:
Shanshan Pan, Luan Yin, Jie Liu, Jie Tong, Zichuan Wang, Jiahui Zhao, Xuesong Liu, Yong Chen, Jing Miao, Yuan Zhou, Su Zeng, Tengfei Xu
Publikováno v:
MedComm, Vol 5, Iss 11, Pp n/a-n/a (2024)
Abstract Identification of therapeutic targets can directly elucidate the mechanism and effect of drug therapy, which is a central step in drug development. The disconnect between protein targets and phenotypes under complex mechanisms hampers compre
Externí odkaz:
https://doaj.org/article/118552e1b22746ceb95d94c4c8d0e69b
Publikováno v:
Pharmacological Research, Vol 207, Iss , Pp 107332- (2024)
The endoplasmic reticulum (ER) plays a pivotal role in protein folding and secretion, Ca2+ storage, and lipid synthesis in eukaryotic cells. When the burden of protein synthesis and folding required to be handled exceeds the processing capacity of th
Externí odkaz:
https://doaj.org/article/1e8101fd7d15460d9ff37db7c9b0bb23
Publikováno v:
Chinese Medicine, Vol 18, Iss 1, Pp 1-20 (2023)
Abstract Background Rhein can significantly delay the progression of chronic nephropathy. However, its mechanism of action has not been adequately elaborated, which hinders its extensive clinical application. In this work, the effects of rhein on mod
Externí odkaz:
https://doaj.org/article/8bfd82af8e104e73a9b29bbbb7f43d71
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 12, Iss 6, Pp 815-823 (2022)
In recent years, scientific researchers have increasingly become interested in noninvasive sampling methods for therapeutic drug monitoring and disease diagnosis. As a result, dried saliva spot (DSS), which is a sampling technique for collecting drie
Externí odkaz:
https://doaj.org/article/b34e723338054cb2b2ccad1b3ee98561
Autor:
Lu Chen, Yuchen Wang, Qingqing Hu, Yuxi Liu, Xuchen Qi, Zhihua Tang, Haihong Hu, Nengming Lin, Su Zeng, Lushan Yu
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The tumor microenvironment (TME) is a crucial driving factor for tumor progression and it can hinder the body’s immune response by altering the metabolic activity of immune cells. Both tumor and immune cells maintain their proliferative characteris
Externí odkaz:
https://doaj.org/article/332794c4910644d09171cab0243af2d7
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 11, Iss 4, Pp 505-514 (2021)
The aim of this study was to develop a diagnostic strategy for esophageal squamous cell carcinoma (ESCC) that combines plasma metabolomics with machine learning algorithms. Plasma-based untargeted metabolomics analysis was performed with samples deri
Externí odkaz:
https://doaj.org/article/baaed31d043e47da8514e3d745216871
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Human UDP-glucuronosyltransferase (UGT) 2B7 is a crucial phase II metabolic enzyme that transfers glucuronic acid from UDP-glucuronic acid (UDPGA) to endobiotic and xenobiotic substrates. Biophysical and biochemical investigations of UGT2B7 are hampe
Externí odkaz:
https://doaj.org/article/a64d196d64364d118a0dfefaf891bb77
Autor:
Yanhong Wang, Jiaqi Wang, Lingrong Yang, Liqing Qiu, Yuhui Hua, Shixiu Wu, Su Zeng, Lushan Yu, Xiaoli Zheng
Publikováno v:
Cell Death and Disease, Vol 12, Iss 6, Pp 1-15 (2021)
Abstract Human intestinal peptide transporter PEPT1 is commonly repressed in human colorectal cancer (CRC), yet its relationship with sensitivity to the common CRC treatment ubenimex has not previously been elucidated. In this study, we confirmed PEP
Externí odkaz:
https://doaj.org/article/2ded6eb909504d9c8ee9726f6b125df2
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 2318-2328 (2021)
An appropriate therapeutic index is crucial for drug discovery and development since narrow therapeutic index (NTI) drugs with slight dosage variation may induce severe adverse drug reactions or potential treatment failure. To date, the shared charac
Externí odkaz:
https://doaj.org/article/5c0bbc9b09c44cd29fca6183f362304c