Chronic lymphocytic leukemia presence impairs antigen-specific CD8+ T-cell responses through epigenetic reprogramming towards short-lived effectors

Autor: Anne W. J. Martens, Inga Kavazović, Mia Krapić, Su Min Pack, Ramon Arens, Aldo Jongejan, Perry D. Moerland, Eric Eldering, Gerritje J. W. van der Windt, Felix M. Wensveen, Fleur S. Peters, Arnon P. Kater

Publikováno v: Leukemia, 1-11. Nature Publishing Group
STARTPAGE=1;ENDPAGE=11;ISSN=0887-6924;TITLE=Leukemia
Leukemia, 37, 606-616. SPRINGERNATURE
Leukemia
Volume 37

T-cell dysregulation in chronic lymphocytic leukemia (CLL) associates with low response rates to autologous T cell-based therapies. How CLL affects antigen-specific T-cell responses remains largely unknown. We investigated (epi)genetic and functional

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4913b98a4d25cb7dce2df04195881459
https://doi.org/10.1038/s41375-023-01817-z

Chronic lymphocytic leukemia presence impairs antigen-specific CD8+ T-cell responses through epigenetic reprogramming towards short-lived effectors

Autor: Anne Martens, Inga Kavazovic, Su Min Pack, Ramon Arens, Aldo Jongejan, Perry Moerland, Eric Eldering, gerritje windt van der, felix wensveen, Fleur Peters, Arnon Kater

T-cell dysregulation in chronic lymphocytic leukemia (CLL) associates with low response rates to autologous T cell-based therapies. How CLL affects antigen-specific T-cell responses remains largely unknown. We investigated (epi)genetic and functional

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::22a73bbd03eb23452ac01bd0f26760c3
https://doi.org/10.21203/rs.3.rs-1829072/v1

Studies from University of Amsterdam Have Provided New Data on Chronic Lymphocytic Leukemia [Chronic Lymphocytic Leukemia Presence Impairs Antigen-specific Cd8(+) T-cell Responses Through Epigenetic Reprogramming Towards Short-lived Effectors].

Publikováno v: Hematology Week; 2/28/2023, p1787-1787, 1p