Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Su Kit Chew"'
Autor:
Sebastijan Hobor, Maise Al Bakir, Crispin T. Hiley, Marcin Skrzypski, Alexander M. Frankell, Bjorn Bakker, Thomas B. K. Watkins, Aleksandra Markovets, Jonathan R. Dry, Andrew P. Brown, Jasper van der Aart, Hilda van den Bos, Diana Spierings, Dahmane Oukrif, Marco Novelli, Turja Chakrabarti, Adam H. Rabinowitz, Laila Ait Hassou, Saskia Litière, D. Lucas Kerr, Lisa Tan, Gavin Kelly, David A. Moore, Matthew J. Renshaw, Subramanian Venkatesan, William Hill, Ariana Huebner, Carlos Martínez-Ruiz, James R. M. Black, Wei Wu, Mihaela Angelova, Nicholas McGranahan, Julian Downward, Juliann Chmielecki, Carl Barrett, Kevin Litchfield, Su Kit Chew, Collin M. Blakely, Elza C. de Bruin, Floris Foijer, Karen H. Vousden, Trever G. Bivona, TRACERx consortium, Robert E. Hynds, Nnennaya Kanu, Simone Zaccaria, Eva Grönroos, Charles Swanton
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract The phenomenon of mixed/heterogenous treatment responses to cancer therapies within an individual patient presents a challenging clinical scenario. Furthermore, the molecular basis of mixed intra-patient tumor responses remains unclear. Here
Externí odkaz:
https://doaj.org/article/a58c4b29e1d8491b8078212067633916
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Mutations in VHL have been linked to clear cell renal cancer, but the molecular mechanisms involved remain unclear. Here the authors generate a mouse model closely mimicking the human disease and show that VHL loss induces DNA replication stress that
Externí odkaz:
https://doaj.org/article/2a15b52553454c128bb092ae2e0904c7
Autor:
Monte M. Winslow, Charles Swanton, Dmitri A. Petrov, Christopher D. McFarland, Le Cong, Christian A. Kunder, Wen-Yang Lin, Maryam Yousefi, Shi Ya C. Lee, Leo C. Chen, King L. Hung, Rui Tang, Emily L. Ashkin, Emily G. Shuldiner, Nicholas W. Hughes, Christopher W. Murray, Laura Andrejka, Min K. Tsai, Chuan Li, Su Kit Chew, Hongchen Cai
(Updated, with minor text changes and rearrangements.) Figure S1-S4 (related to Figure 1) provide details on the selected genes and method. Figure S5 (related to Figure 2) shows the percentiles of all sgRNAs. Figure S6-S8 (related to Figure 3) presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb999fe9b53b0a94ffbad60dec52b16e
https://doi.org/10.1158/2159-8290.22540429
https://doi.org/10.1158/2159-8290.22540429
Autor:
Monte M. Winslow, Charles Swanton, Dmitri A. Petrov, Christopher D. McFarland, Le Cong, Christian A. Kunder, Wen-Yang Lin, Maryam Yousefi, Shi Ya C. Lee, Leo C. Chen, King L. Hung, Rui Tang, Emily L. Ashkin, Emily G. Shuldiner, Nicholas W. Hughes, Christopher W. Murray, Laura Andrejka, Min K. Tsai, Chuan Li, Su Kit Chew, Hongchen Cai
Cancer genotyping has identified a large number of putative tumor suppressor genes. Carcinogenesis is a multistep process, but the importance and specific roles of many of these genes during tumor initiation, growth, and progression remain unknown. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b404e969247084e511f71eff4ac10a
https://doi.org/10.1158/2159-8290.c.6549376
https://doi.org/10.1158/2159-8290.c.6549376
Autor:
Monte M. Winslow, Charles Swanton, Dmitri A. Petrov, Christopher D. McFarland, Le Cong, Christian A. Kunder, Wen-Yang Lin, Maryam Yousefi, Shi Ya C. Lee, Leo C. Chen, King L. Hung, Rui Tang, Emily L. Ashkin, Emily G. Shuldiner, Nicholas W. Hughes, Christopher W. Murray, Laura Andrejka, Min K. Tsai, Chuan Li, Su Kit Chew, Hongchen Cai
Table S2. The information of sgRNA vectors in the high content Lenti-sgTS102/Cre pool.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bd3cce0b27516cffd3dcfa9479b7b40
https://doi.org/10.1158/2159-8290.22540423
https://doi.org/10.1158/2159-8290.22540423
Autor:
Monte M. Winslow, Dmitri A. Petrov, Christian A. Kunder, Charles Swanton, Pauline Chu, Su-Kit Chew, Caterina I. Colón, Pegah Yakhchalian, Chuan Li, Wen-Yang Lin, Min K. Tsai, Minwei Wang, Leo Chen, Laura Andrejka, Saswati Karmakar, Emily L. Ashkin, Hongchen Cai, Jess D. Hebert, Christopher W. Murray, Carly Weiss, Gábor Boross, Maryam Yousefi
Supplementary Table from Combinatorial Inactivation of Tumor Suppressors Efficiently Initiates Lung Adenocarcinoma with Therapeutic Vulnerabilities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::042b103656126ba4dbaf5850295d0cba
https://doi.org/10.1158/0008-5472.22430772.v1
https://doi.org/10.1158/0008-5472.22430772.v1
Autor:
Monte M. Winslow, Dmitri A. Petrov, Christian A. Kunder, Charles Swanton, Pauline Chu, Su-Kit Chew, Caterina I. Colón, Pegah Yakhchalian, Chuan Li, Wen-Yang Lin, Min K. Tsai, Minwei Wang, Leo Chen, Laura Andrejka, Saswati Karmakar, Emily L. Ashkin, Hongchen Cai, Jess D. Hebert, Christopher W. Murray, Carly Weiss, Gábor Boross, Maryam Yousefi
Lung cancer is the leading cause of cancer death worldwide, with lung adenocarcinoma being the most common subtype. Many oncogenes and tumor suppressor genes are altered in this cancer type, and the discovery of oncogene mutations has led to the deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc114c2b785293faf863f3455b7de909
https://doi.org/10.1158/0008-5472.c.6513717.v1
https://doi.org/10.1158/0008-5472.c.6513717.v1
Autor:
Monte M. Winslow, Dmitri A. Petrov, Christian A. Kunder, Charles Swanton, Pauline Chu, Su-Kit Chew, Caterina I. Colón, Pegah Yakhchalian, Chuan Li, Wen-Yang Lin, Min K. Tsai, Minwei Wang, Leo Chen, Laura Andrejka, Saswati Karmakar, Emily L. Ashkin, Hongchen Cai, Jess D. Hebert, Christopher W. Murray, Carly Weiss, Gábor Boross, Maryam Yousefi
Supplementary Data from Combinatorial Inactivation of Tumor Suppressors Efficiently Initiates Lung Adenocarcinoma with Therapeutic Vulnerabilities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7855b95605a95a915f9e9ff3b567f9d6
https://doi.org/10.1158/0008-5472.22430793
https://doi.org/10.1158/0008-5472.22430793
Autor:
Monte M. Winslow, Dmitri A. Petrov, Christian A. Kunder, Charles Swanton, Pauline Chu, Su-Kit Chew, Caterina I. Colón, Pegah Yakhchalian, Chuan Li, Wen-Yang Lin, Min K. Tsai, Minwei Wang, Leo Chen, Laura Andrejka, Saswati Karmakar, Emily L. Ashkin, Hongchen Cai, Jess D. Hebert, Christopher W. Murray, Carly Weiss, Gábor Boross, Maryam Yousefi
Supplementary Figure from Combinatorial Inactivation of Tumor Suppressors Efficiently Initiates Lung Adenocarcinoma with Therapeutic Vulnerabilities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c95b9c41fc2a3701dc8ec01b4cb3609
https://doi.org/10.1158/0008-5472.22430790
https://doi.org/10.1158/0008-5472.22430790
Autor:
Maryam Yousefi, Gábor Boross, Carly Weiss, Christopher W. Murray, Jess D. Hebert, Hongchen Cai, Emily L. Ashkin, Saswati Karmakar, Laura Andrejka, Leo Chen, Minwei Wang, Min K. Tsai, Wen-Yang Lin, Chuan Li, Pegah Yakhchalian, Caterina I. Colón, Su-Kit Chew, Pauline Chu, Charles Swanton, Christian A. Kunder, Dmitri A. Petrov, Monte M. Winslow
Publikováno v:
Cancer Res
Lung cancer is the leading cause of cancer death worldwide, with lung adenocarcinoma being the most common subtype. Many oncogenes and tumor suppressor genes are altered in this cancer type, and the discovery of oncogene mutations has led to the deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::547e86d94682d3deb4c872b757dd5fec
https://doi.org/10.1158/0008-5472.can-22-0059
https://doi.org/10.1158/0008-5472.can-22-0059