Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Su Jung Song"'
Autor:
Jae Heon Kim, Hee Jo Yang, Kwang Woo Lee, Jae Joon Park, Chang-Ho Lee, Youn Soo Jeon, Jae Ho Kim, Suyeon Park, Su Jung Song, Ji-Hye Lee, Ahrim Moon, Yon Hee Kim, Yun Seob Song
Publikováno v:
Pharmaceuticals, Vol 16, Iss 12, p 1703 (2023)
Background: Ubiquitin-specific protease 11 (USP11), one of the principal phosphatase and tensin homolog (PTEN) deubiquitinases, can reserve PTEN polyubiquitination to maintain PTEN protein integrity and inhibit PI3K/AKT pathway activation. The aim of
Externí odkaz:
https://doaj.org/article/cfac16977dbc47aa99c6e00d0099a056
Autor:
Tao Han, Shulong Jiang, Hong Zheng, Qing Yin, Mengyu Xie, Margaret R Little, Xiu Yin, Ming Chen, Su Jung Song, Amer A. Beg, Pier Paolo Pandolfi, Lixin Wan
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
The Anaphase Promoting Complex adaptor protein Cdh1 tightly controls cell cycle progression to restrain tumorigenesis but the mechanism is not completely known. Here, the authors show that reciprocal inhibition between Cdh1 and the c-Src signaling pa
Externí odkaz:
https://doaj.org/article/0384f8d299bb452ab948ffee2b150f84
Autor:
Mi Kyung Park, Yixin Yao, Weiya Xia, Stephanie Rebecca Setijono, Jae Hwan Kim, Isabelle K. Vila, Hui-Hsuan Chiu, Yun Wu, Enrique González Billalabeitia, Min Gyu Lee, Robert G. Kalb, Mien-Chie Hung, Pier Paolo Pandolfi, Su Jung Song, Min Sup Song
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
PTEN is a lipid phosphatase that functions as a dose-dependent tumor suppressor through the PI3K/AKT pathway. Here the authors describe a signaling feedback mechanism where PTEN stability is regulated through transcriptional upregulation of X-linked
Externí odkaz:
https://doaj.org/article/b1a406900145437995bad2a50a3a9b15
Autor:
Jae-Heon Kim, Hee-Jo Yang, Chang-Ho Lee, Youn-Soo Jeon, Jae-Joon Park, Kwang-Woo Lee, Jae-Ho Kim, Su-Yeon Park, Su-Jung Song, Yon-Hee Kim, Ah-Rim Moon, Ji-Hye Lee, Yun-Seob Song
Publikováno v:
Pharmaceuticals, Vol 14, Iss 8, p 778 (2021)
Background: The mTOR signaling pathway is inactivated by AMPK’s tumor-suppressing function. It is recognized that ubiquitin conjugating enzyme 2O (UBE2O), which directly targets AMPK for ubiquitination and degradation, is intensified in human cance
Externí odkaz:
https://doaj.org/article/9ebcef769bfc48f9af809579b4abe8d8
Autor:
Pier Paolo Pandolfi, Lewis C. Cantley, John G. Clohessy, Caterina Nardella, John M. Asara, Massimo Loda, Sabina Signoretti, Kaitlyn A. Webster, Christopher Ng, Andrea Lunardi, Ming Chen, Robin M. Hobbs, Antonella Papa, Mirjam T. Epping, Xue-Song Liu, Akash Patnaik, Min Sup Song, Su Jung Song, Nina Seitzer, Enrique González-Billalabeitia
PDF - 14407K, Supporting histology for Olaparib treatment in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353dca42c04c1e11621ce8aa8404957c
https://doi.org/10.1158/2159-8290.22530389.v1
https://doi.org/10.1158/2159-8290.22530389.v1
Autor:
Pier Paolo Pandolfi, Lewis C. Cantley, John G. Clohessy, Caterina Nardella, John M. Asara, Massimo Loda, Sabina Signoretti, Kaitlyn A. Webster, Christopher Ng, Andrea Lunardi, Ming Chen, Robin M. Hobbs, Antonella Papa, Mirjam T. Epping, Xue-Song Liu, Akash Patnaik, Min Sup Song, Su Jung Song, Nina Seitzer, Enrique González-Billalabeitia
PDF - 632K, Preclinical assessment of Olaparib and BKM120 treatment in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b05838e2cd1167f3054489299120db17
https://doi.org/10.1158/2159-8290.22530383
https://doi.org/10.1158/2159-8290.22530383
Autor:
Pier Paolo Pandolfi, Lewis C. Cantley, John G. Clohessy, Caterina Nardella, John M. Asara, Massimo Loda, Sabina Signoretti, Kaitlyn A. Webster, Christopher Ng, Andrea Lunardi, Ming Chen, Robin M. Hobbs, Antonella Papa, Mirjam T. Epping, Xue-Song Liu, Akash Patnaik, Min Sup Song, Su Jung Song, Nina Seitzer, Enrique González-Billalabeitia
PDF - 546K, Olaparib induces a differing response in vitro depending on the genetic background.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::724c5df3b489d8e7fe10a26273c7cf1b
https://doi.org/10.1158/2159-8290.22530395
https://doi.org/10.1158/2159-8290.22530395
Autor:
Pier Paolo Pandolfi, Lewis C. Cantley, John G. Clohessy, Caterina Nardella, John M. Asara, Massimo Loda, Sabina Signoretti, Kaitlyn A. Webster, Christopher Ng, Andrea Lunardi, Ming Chen, Robin M. Hobbs, Antonella Papa, Mirjam T. Epping, Xue-Song Liu, Akash Patnaik, Min Sup Song, Su Jung Song, Nina Seitzer, Enrique González-Billalabeitia
PDF - 2951K, Olaparib induces a differing response in vivo depending on the genetic background.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50e4a480b047ac01e7c7e331a2822f54
https://doi.org/10.1158/2159-8290.22530392
https://doi.org/10.1158/2159-8290.22530392
Autor:
Pier Paolo Pandolfi, Lewis C. Cantley, John G. Clohessy, Caterina Nardella, John M. Asara, Massimo Loda, Sabina Signoretti, Kaitlyn A. Webster, Christopher Ng, Andrea Lunardi, Ming Chen, Robin M. Hobbs, Antonella Papa, Mirjam T. Epping, Xue-Song Liu, Akash Patnaik, Min Sup Song, Su Jung Song, Nina Seitzer, Enrique González-Billalabeitia
PDF - 114k, Supporting western blot analysis and drug treatment in prostate cancer cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::221dbca83b464ebaef9005cd812ae840
https://doi.org/10.1158/2159-8290.22530386
https://doi.org/10.1158/2159-8290.22530386
Autor:
Pier Paolo Pandolfi, Lewis C. Cantley, John G. Clohessy, Caterina Nardella, John M. Asara, Massimo Loda, Sabina Signoretti, Kaitlyn A. Webster, Christopher Ng, Andrea Lunardi, Ming Chen, Robin M. Hobbs, Antonella Papa, Mirjam T. Epping, Xue-Song Liu, Akash Patnaik, Min Sup Song, Su Jung Song, Nina Seitzer, Enrique González-Billalabeitia
PDF - 116K, Supplementary Materials and Methods and Supplementary Figure Legends.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87fae1949355907d4f0ba859a6cea868
https://doi.org/10.1158/2159-8290.22530368.v1
https://doi.org/10.1158/2159-8290.22530368.v1