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Akademický článek

Structure–Activity relationship (SAR) of 18β-glycyrrhetinic acid derivatives on their antitumor activity through the PPARγ receptor and caspase-3 pathway

Autor: Juan Sun, Qi Zheng, Yi-Heng Zhang, Cai-Shi Liu, Chong-Hao Chen, Shao-Peng Yan, Xiao-Meng Guo, Su-Pei Hu, Yang Zhou, Yuan-Feng Wu

Publikováno v: Journal of Saudi Chemical Society, Vol 28, Iss 2, Pp 101815- (2024)

Licorice is extensively utilized in the food industry, and glycyrrhetinic acid is among the most critical active constituents in licorice. This ingredient has garnered increasing attention in recent years. In a previous study, we identified a new ser

Externí odkaz: https://doaj.org/article/729438c8d9724890b31c4b791893f612

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Akademický článek

Microarray Analysis of Long Noncoding RNAs in Female Diabetic Peripheral Neuropathy Patients

Autor: Lin Luo, Lin-Dan Ji, Jiang-Jia Cai, Mei Feng, Mi Zhou, Su-Pei Hu, Jin Xu, Wen-Hua Zhou

Publikováno v: Cellular Physiology and Biochemistry, Vol 46, Iss 3, Pp 1209-1217 (2018)

Background/Aims: Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes mellitus (DM). Because of its controversial pathogenesis, DPN is still not diagnosed or managed properly in most patients. Methods: In this study, human

Externí odkaz: https://doaj.org/article/a61e4d577de24ef18fc300f1c5356c2f

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Akademický článek

Gene Expression Profiling Identifies Downregulation of the Neurotrophin-MAPK Signaling Pathway in Female Diabetic Peripheral Neuropathy Patients

Autor: Lin Luo, Wen-Hua Zhou, Jiang-Jia Cai, Mei Feng, Mi Zhou, Su-Pei Hu, Jin Xu, Lin-Dan Ji

Publikováno v: Journal of Diabetes Research, Vol 2017 (2017)

Diabetic peripheral neuropathy (DPN) is a common complication of diabetes mellitus (DM). It is not diagnosed or managed properly in the majority of patients because its pathogenesis remains controversial. In this study, human whole genome microarrays

Externí odkaz: https://doaj.org/article/9510d8272bc344159e48ba9c8d64b12b

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Design, Synthesis and Antibacterial Activities of Novel Amide Derivatives Bearing Dioxygenated Rings as Potential β-Ketoacyl-acyl Carrier Protein Synthase III (FabH) Inhibitors

Autor: Yang Zhou, Yin-Qiu Liang, Xin-Yu Wang, Hao-Yun Chang, Su-Pei Hu, Juan Sun

Publikováno v: Chemicalpharmaceutical bulletin. 70(8)

Fatty acid biosynthesis is essential for bacterial survival. Of these promising targets, β-ketoacyl-acyl carrier protein (ACP) synthase III (FabH) is the most attractive target. FabH would trigger the initiation of fatty acid biosynthesis and it is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::725432fca630b8e4353b19d087c7ad6e
https://pubmed.ncbi.nlm.nih.gov/35908920

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Autor: Hai‐Zhong Liu, Bo Yu, Jin-Cheng Guo, Jin-Na Liu, Su‐Pei Hu, Yuhan Gao, Shuangsang Fang, Yi Zhao, Shuai Hong, Liang Sun, Jian-Hua Zhang

Publikováno v: Journal of Cellular Physiology. 235:3569-3578

Studies have shown that microRNAs (miRNAs) play a vital role in tumor progression and patients' prognosis. Therefore, we aimed to construct a miRNA model for forecasting the survival of hepatocellular carcinoma (HCC) patients. The gene expression dat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2e111e20099dd50d697d933f12b6d44
https://doi.org/10.1002/jcp.29245

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Identification of functional lncRNAs based on competing endogenous RNA network in osteoblast differentiation

Autor: Su‐Pei Hu, Liang Chen, Zhengyang Kang, Zhiguo Liu, Wenhui Ruan, Yongzhi Zhang, Liang Sun, Shuai Hong, Weibin Yang, Dengfeng Yang, Guoyong Yu

Publikováno v: Journal of Cellular Physiology. 235:2232-2244

Adult human mesenchymal stem cells have the potential to differentiate into osteoblast, which plays crucial roles in bone regeneration and repair. Some transcriptional factors (TFs), such as BMP-2 and RUNX2, have been demonstrated to control the diff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdd26d7c75ad0ef6234045d3a2a766a9
https://doi.org/10.1002/jcp.29132

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Microarray Analysis of Long Noncoding RNAs in Female Diabetic Peripheral Neuropathy Patients

Autor: Mei Feng, Su-Pei Hu, Mi Zhou, Jin Xu, Wen-Hua Zhou, Lin Luo, Lin-dan Ji, Jiang-Jia Cai

Publikováno v: Cellular Physiology and Biochemistry, Vol 46, Iss 3, Pp 1209-1217 (2018)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ac4409b976c68981dfad893f0a0bf06
https://doi.org/10.1159/000489071

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Gene Expression Profiling Identifies Downregulation of the Neurotrophin-MAPK Signaling Pathway in Female Diabetic Peripheral Neuropathy Patients

Autor: Su-Pei Hu, Mi Zhou, Jiang-Jia Cai, Lin Luo, Jin Xu, Lin-dan Ji, Mei Feng, Wen-Hua Zhou

Publikováno v: Journal of Diabetes Research
Journal of Diabetes Research, Vol 2017 (2017)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::999800464d4a19fd38754c694b432ac9
https://doi.org/10.1155/2017/8103904

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Gender-Specific Association of ATP2B1 Variants with Susceptibility to Essential Hypertension in the Han Chinese Population

Autor: Mi Zhou, Jia Su, Li-ya Liu, Mei Feng, Su-Pei Hu, Lin-dan Ji, Jin Xu, Hai-xia Qian

Publikováno v: BioMed Research International
BioMed Research International, Vol 2016 (2016)

Previous genome-wide association studies (GWASs) found that severalATP2B1variants are associated with essential hypertension (EHT). But the “genome-wide significant”ATP2B1SNPs (rs2681472, rs2681492, rs17249754, and rs1105378) are in strong linkag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59bb3111bbd2225e511d9d4d41faaa07

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