Smart Release Nano-formulation of Cytochrome C and Hyaluronic Acid Induces Apoptosis in Cancer Cells

Autor: Kai Griebenow, Zally Torres, Cindy M Figueroa, Anna M. Molina, Suárez Bn, Fernández Jc

Publikováno v: Journal of nanomedicine & nanotechnology

Herein we tested a nanosized cancer-cell targeted delivery system based on cytochrome c (Cyt c) and hyaluronic acid. Cyt c was chosen since it is a per se non-toxic protein but causes apoptosis when delivered to the cytoplasm of target cells. Hyaluro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b77c74ca307be8e6f5c678e4db1f7a
https://pubmed.ncbi.nlm.nih.gov/28706754

Induction of Cancer Cell Death by Hyaluronic Acid-Mediated Uptake of Cytochrome C.

Autor: Figueroa CM; Department of Chemistry, University of Puerto Rico, Río Piedras Campus, San Juan, PR 00931, USA., Morales-Cruz M; Department of Biology, University of Puerto Rico, Río Piedras Campus, San Juan, PR 00931, USA., Suárez BN; Department of Chemistry, University of Puerto Rico, Río Piedras Campus, San Juan, PR 00931, USA., Fernández JC; Department of Biology, University of Puerto Rico, Río Piedras Campus, San Juan, PR 00931, USA., Molina AM; Department of Chemistry, University of Puerto Rico, Río Piedras Campus, San Juan, PR 00931, USA., Quiñones CM; Department of Chemistry, University of Puerto Rico, Río Piedras Campus, San Juan, PR 00931, USA., Griebenow K; Department of Chemistry, University of Puerto Rico, Río Piedras Campus, San Juan, PR 00931, USA.

Publikováno v: Journal of nanomedicine & nanotechnology [J Nanomed Nanotechnol] 2015 Oct; Vol. 6 (5). Date of Electronic Publication: 2015 Oct 01.