Design, green synthesis, and anti-glutamate damage screening of chalcone derivatives with spiro-heterocyclic structures as potential anti-ischemic brain and eye damage agents

Autor: Wu, Jianzhang, Huang, Chenyang, Ren, Shuo, Wu, Tao, Li, Yujia, Zhong, Hongliang, Su, Tiande, Chen, Yinqi, Tan, Xiangpeng, Wu, Wencan, Wang, Jingsong, Li, Wulan

Publikováno v: In Bioorganic Chemistry December 2024 153

Discovery and evaluation of chalcone derivatives as novel potential anti-Toxoplasma gondii agents

Autor: Jiang, Liping, Liu, Bo, Hou, Shengjie, Su, Tiande, Fan, Qiyun, Alyafeai, Eman, Tang, Yaqin, Wu, Mengqi, Liu, Xiaohua, Li, Jing, Hu, Yu, Li, Wulan, Zheng, Zhiwei, Liu, Yuan, Wu, Jianzhang

Publikováno v: In European Journal of Medicinal Chemistry 15 April 2022 234

Design, synthesis, and evaluation of cyclic C7-bridged monocarbonyl curcumin analogs containing an o -methoxy phenyl group as potential agents against gastric cancer.

Autor: Gan X; The Second Affiliated Hospital and Yuying Children's Hospital of the Wenzhou Medical University, Wenzhou, China.; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Wenzhou, China.; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China., Wu Y; The Eye Hospital, School of Ophthalmology & Optometry, Wenzhou Medical University, Wenzhou, China., Zhu M; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China., Liu B; The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China., Kong M; The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China., Xi Z; The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China., Li K; The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China., Wang H; Municipal Hospital Affiliated to Taizhou University, Taizhou, China., Su T; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China., Yao J; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China., Khushafah F; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China., Yi B; The Second Affiliated Hospital and Yuying Children's Hospital of the Wenzhou Medical University, Wenzhou, China., Wang J; Municipal Hospital Affiliated to Taizhou University, Taizhou, China., Li W; The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China., Wu J; The Second Affiliated Hospital and Yuying Children's Hospital of the Wenzhou Medical University, Wenzhou, China.; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Wenzhou, China.; The Eye Hospital, School of Ophthalmology & Optometry, Wenzhou Medical University, Wenzhou, China.

Publikováno v: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2024 Dec; Vol. 39 (1), pp. 2314233. Date of Electronic Publication: 2024 Feb 22.