Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Styrmir Sigurjonsson"'
Autor:
Eser Kirkizlar, Bernhard Zimmermann, Tudor Constantin, Ryan Swenerton, Bin Hoang, Nicholas Wayham, Joshua E. Babiarz, Zachary Demko, Robert J. Pelham, Stephanie Kareht, Alexander L. Simon, Kristine N. Jinnett, Matthew Rabinowitz, Styrmir Sigurjonsson, Matthew Hill
Publikováno v:
Translational Oncology, Vol 8, Iss 5, Pp 407-416 (2015)
We demonstrate proof-of-concept for the use of massively multiplexed PCR and next-generation sequencing (mmPCR-NGS) to identify both clonal and subclonal copy-number variants (CNVs) in circulating tumor DNA. This is the first report of a targeted met
Externí odkaz:
https://doaj.org/article/7d066fbaf8d04bb1b6461ca5636564b1
Autor:
Rajiv C McCoy, Zachary P Demko, Allison Ryan, Milena Banjevic, Matthew Hill, Styrmir Sigurjonsson, Matthew Rabinowitz, Dmitri A Petrov
Publikováno v:
PLoS Genetics, Vol 11, Iss 10, p e1005601 (2015)
Whole-chromosome imbalances affect over half of early human embryos and are the leading cause of pregnancy loss. While these errors frequently arise in oocyte meiosis, many such whole-chromosome abnormalities affecting cleavage-stage embryos are the
Externí odkaz:
https://doaj.org/article/302e7261c8504e16a09a097e6af752b3
Autor:
Megan P Hall, Matthew Hill, Bernhard Zimmermann, Styrmir Sigurjonsson, Margaret Westemeyer, Jennifer Saucier, Zachary Demko, Matthew Rabinowitz
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96677 (2014)
PURPOSE:To determine how a single nucleotide polymorphism (SNP)- and informatics-based non-invasive prenatal aneuploidy test performs in detecting trisomy 13. METHODS:Seventeen trisomy 13 and 51 age-matched euploid samples, randomly selected from a l
Externí odkaz:
https://doaj.org/article/5845311b4bc8454aacf11836f7a23bb9
Autor:
Ruth B. Lathi, Jamie A. M. Massie, Megan Loring, Zachary P. Demko, David Johnson, Styrmir Sigurjonsson, George Gemelos, Matthew Rabinowitz
Publikováno v:
PLoS ONE, Vol 7, Iss 8 (2012)
Externí odkaz:
https://doaj.org/article/c38d8f98b4b44ab880a156843bb22786
Autor:
Ruth B Lathi, Jamie A M Massie, Megan Loring, Zachary P Demko, David Johnson, Styrmir Sigurjonsson, George Gemelos, Matthew Rabinowitz
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e31282 (2012)
PURPOSE: The metaphase karyotype is often used as a diagnostic tool in the setting of early miscarriage; however this technique has several limitations. We evaluate a new technique for karyotyping that uses single nucleotide polymorphism microarrays
Externí odkaz:
https://doaj.org/article/b2073bcce1734957be61077fe2171dc4
Autor:
Thomas Reinert, Katrine Stribolt, Zoe June Assaf, Lene Hjerrild Iversen, Matthew Rabinowitz, Ryan Swenerton, Ramya Srinivasan, Samantha Navarro, Lars Dyrskjøt, Claus L. Andersen, Tenna V Henriksen, Anne-Sofie Kannerup, Søren Vang, Alexander Olson, Shruti Goel, Alexey Aleshin, Michael Knudsen, Scott Dashner, Styrmir Sigurjonsson, Mustafa Balcioglu, Emil Christensen, Anders Husted Madsen, Cheng-Ho Jimmy Lin, Raheleh Salari, Paul Billings, Himanshu Sethi, Søren Krag, Mads Rasmussen, Søren Laurberg, Shruti Sharma, Bernhard Zimmermann, Svetlana Shchegrova, Amanda Frydendahl Boll Johansen, Antony Tin, Dina Hafez, Hsin-Ta Wu, Iver Nordentoft, Kåre Gotschalck Sunesen
Publikováno v:
Reinert, T, Henriksen, T V, Christensen, E, Sharma, S, Salari, R, Sethi, H, Knudsen, M, Nordentoft, I, Wu, H-T, Tin, A S, Heilskov Rasmussen, M, Vang, S, Shchegrova, S, Frydendahl Boll Johansen, A, Srinivasan, R, Assaf, Z, Balcioglu, M, Olson, A, Dashner, S, Hafez, D, Navarro, S, Goel, S, Rabinowitz, M, Billings, P, Sigurjonsson, S, Dyrskjøt, L, Swenerton, R, Aleshin, A, Laurberg, S, Husted Madsen, A, Kannerup, A-S, Stribolt, K, Palmelund Krag, S, Iversen, L H, Gotschalck Sunesen, K, Lin, C-H J, Zimmermann, B G & Lindbjerg Andersen, C 2019, ' Analysis of Plasma Cell-Free DNA by Ultradeep Sequencing in Patients With Stages I to III Colorectal Cancer ', JAMA Oncology, vol. 5, no. 8, pp. 1124-1131 . https://doi.org/10.1001/jamaoncol.2019.0528
Importance: Novel sensitive methods for detection and monitoring of residual disease can improve postoperative risk stratification with implications for patient selection for adjuvant chemotherapy (ACT), ACT duration, intensity of radiologic surveill
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c59acf069d0b5229abc11521aab11d94
https://pure.au.dk/ws/files/197692926/jamaoncology_reinert_2019_oi_190019.pdf
https://pure.au.dk/ws/files/197692926/jamaoncology_reinert_2019_oi_190019.pdf
Autor:
Ryan Swenerton, Lars Dyrskjøt, Dina Hafez, Zoe June Assaf, Alexey Aleshin, Mads Agerbæk, Samantha Navarro, Hsin-Ta Wu, Claus L. Andersen, Ramya Srinivasan, Emil Christensen, Antony Tin, Scott Dashner, Iver Nordentoft, Mustafa Balcioglu, Jørgen Bjerggaard Jensen, Karin Birkenkamp-Demtröder, Styrmir Sigurjonsson, Michael Knudsen, Sia Viborg Lindskrog, Bernhard Zimmermann, Philippe Lamy, Cheng-Ho Jimmy Lin, Ann Taber, Søren Vang, Alexander Olson, Thomas Reinert, Raheleh Salari, Svetlana Shchegrova, Himanshu Sethi, Shruti Sharma, Rosalyn Ram, Matthew Rabinowitz, Paul Billings
Publikováno v:
Christensen, E, Birkenkamp-Demtröder, K, Sethi, H, Shchegrova, S, Salari, R, Nordentoft, I, Wu, H-T, Knudsen, M, Lamy, P, Lindskrog, S V, Taber, A, Balcioglu, M, Vang, S, Assaf, Z, Sharma, S, Tin, A S, Srinivasan, R, Hafez, D, Reinert, T, Navarro, S, Olson, A, Ram, R, Dashner, S, Rabinowitz, M, Billings, P, Sigurjonsson, S, Andersen, C L, Swenerton, R, Aleshin, A, Zimmermann, B, Agerbæk, M, Lin, C-H J, Jensen, J B & Dyrskjøt, L 2019, ' Early Detection of Metastatic Relapse and Monitoring of Therapeutic Efficacy by Ultra-Deep Sequencing of Plasma Cell-Free DNA in Patients With Urothelial Bladder Carcinoma ', Journal of Clinical Oncology, vol. 37, no. 18, pp. 1547-1557 . https://doi.org/10.1200/JCO.18.02052
PURPOSE Novel sensitive methods for early detection of relapse and for monitoring therapeutic efficacy may have a huge impact on risk stratification, treatment, and ultimately outcome for patients with bladder cancer. We addressed the prognostic and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dc2a7402f41354ed6512f2af9d18c8b
https://pure.au.dk/portal/da/publications/early-detection-of-metastatic-relapse-and-monitoring-of-therapeutic-efficacy-by-ultradeep-sequencing-of-plasma-cellfree-dna-in-patients-with-urothelial-bladder-carcinoma(ae7edf8e-e90c-4709-9f9c-20a1316cbc31).html
https://pure.au.dk/portal/da/publications/early-detection-of-metastatic-relapse-and-monitoring-of-therapeutic-efficacy-by-ultradeep-sequencing-of-plasma-cellfree-dna-in-patients-with-urothelial-bladder-carcinoma(ae7edf8e-e90c-4709-9f9c-20a1316cbc31).html
Autor:
Stephanie Kareht, Onur Sakarya, Charles Swanton, Mariam Jamal-Hanjani, Tudor Constantin, Bernhard Zimmermann, Raheleh Salari, Richard Mitter, Robert J. Pelham, Styrmir Sigurjonsson, Eser Kirkizlar, Stuart Horswell, Gareth A. Wilson
Publikováno v:
Annals of Oncology. 27:862-867
The aim of this pilot study was to assess whether both ubiquitous and heterogeneous somatic mutations could be detected in cell-free DNA (cfDNA) from patients with early-stage non-small-cell lung cancer (NSCLC).Three stage I and one stage II primary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7122901888a88c639000d3bcf9d1a311
https://doi.org/10.1093/annonc/mdw037
https://doi.org/10.1093/annonc/mdw037
Publikováno v:
Prenatal Diagnosis. 35:986-989
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f1f0fd09b414c7366647edf7d0c075c
https://doi.org/10.1002/pd.4636
https://doi.org/10.1002/pd.4636
Autor:
Katrina Merrion, B. Pettersen, Zachary Demko, Michael Young, Sushma Iyengar, Kimberly Martin, Stephanie Kareht, Melissa K. Maisenbacher, Kiyoung Paik, Styrmir Sigurjonsson
Publikováno v:
Molecular Cytogenetics
Background The 22q11.2 deletion syndrome is the most common microdeletion syndrome in livebirths, but data regarding its incidence in other populations is limited and also include ascertainment bias. This study was designed to determine the incidence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::631485344f427ca450f87652c7500df8
https://doi.org/10.1186/s13039-017-0308-6
https://doi.org/10.1186/s13039-017-0308-6