Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Styliani Vakrou"'
Autor:
Arpana Vaniya, Anja Karlstaedt, Damla Gulkok, Tilo Thottakara, Yamin Liu, Sili Fan, Hannah Eades, Styliani Vakrou, Ryuya Fukunaga, Hilary J. Vernon, Oliver Fiehn, M. Roselle Abraham
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 8, Iss , Pp 100073- (2024)
Introduction: Hypertrophic cardiomyopathy (HCM) results from pathogenic variants in sarcomeric protein genes that increase myocyte energy demand and lead to cardiac hypertrophy. However, it is unknown whether a common metabolic trait underlies cardia
Externí odkaz:
https://doaj.org/article/d8cb9d6dcd734514bb112086143d8f7d
Autor:
Styliani Vakrou, Yamin Liu, Li Zhu, Gabriela V. Greenland, Bahadir Simsek, Virginia B. Hebl, Yufan Guan, Kirubel Woldemichael, Conover C. Talbot, Miguel A. Aon, Ryuya Fukunaga, M. Roselle Abraham
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract Hypertrophic cardiomyopathy (HCM) is characterized by phenotypic heterogeneity. We investigated the molecular basis of the cardiac phenotype in two mouse models at established disease stage (mouse-HCM), and human myectomy tissue (human-HCM).
Externí odkaz:
https://doaj.org/article/e365172126d5471c8bde7c2cc906f5f3
Autor:
Styliani Vakrou, Maria A. Nana, Ioannis A. Nanas, Emmeleia Nana-Leventaki, Michael Bonios, Chris Kapelios, John Nanas
Publikováno v:
Hellenic Journal of Cardiology, Vol 61, Iss 4, Pp 256-261 (2020)
Objective: Cardiosphere-derived cells (CDCs) have been shown to reduce infarct size after myocardial infarction (MI). In the present study we investigated the safety and efficacy of global intracoronary administration (GIA) of CDCs or CDC-conditioned
Externí odkaz:
https://doaj.org/article/81b6b3461e464148ad0507ba1b5f1c5f
Autor:
Yamin Liu, Junaid Afzal, Styliani Vakrou, Gabriela V. Greenland, C. Conover Talbot, Virginia B. Hebl, Yufan Guan, Rehan Karmali, Jil C. Tardiff, Leslie A. Leinwand, Jeffrey E. Olgin, Samarjit Das, Ryuya Fukunaga, M. Roselle Abraham
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 6 (2019)
Background: Hypertrophic cardiomyopathy (HCM) is characterized by myocyte hypertrophy and fibrosis. Studies in two mouse models (R92W-TnT/R403Q-MyHC) at early HCM stage revealed upregulation of endothelin (ET1) signaling in both mutants, but TGFβ si
Externí odkaz:
https://doaj.org/article/f0f284719e3944509201f2ec8335d642
Autor:
Stefania Sventzouri, Ioannis Nanas, Styliani Vakrou, Chris Kapelios, Vasilios Sousonis, Titika Sfakianaki, Apostolos Papalois, Antonis S. Manolis, John N. Nanas, Konstantinos Malliaras
Publikováno v:
Hellenic Journal of Cardiology, Vol 59, Iss 4, Pp 217-222 (2018)
Background: The mitochondrial Na+/Ca2+ exchanger (mNCX) has been implicated in the pathogenesis of arrhythmogenicity and myocardial reperfusion injury, rendering its inhibition a potential therapeutic strategy. We examined the effects of CGP-37157, a
Externí odkaz:
https://doaj.org/article/182b57fec3734d46a08bff6ba0fee949
Autor:
Junaid Afzal, MBBS, MS, Angel Chan, MD PhD, Mehmet Fatih Karakas, MD, Kirubel Woldemichael, BS, Styliani Vakrou, MD, Yufan Guan, MD, Jeffrey Rathmell, PhD, Richard Wahl, MD, Martin Pomper, MD, PhD, D. Brian Foster, PhD, Miguel A. Aon, PhD, Benjamin Tsui, PhD, Brian O’Rourke, PhD, M. Roselle Abraham, MD
Publikováno v:
JACC: Basic to Translational Science, Vol 2, Iss 5, Pp 543-560 (2017)
Adult stem cells demonstrate metabolic flexibility that is regulated by cell adhesion status. The authors demonstrate that adherent cells primarily utilize glycolysis, whereas suspended cells rely on oxidative phosphorylation for their ATP needs. Akt
Externí odkaz:
https://doaj.org/article/f7e9e7dda3dc4926bc72f4305223c445
Autor:
David Hurtado-de-Mendoza, MD, Celia P. Corona-Villalobos, MD, Iraklis Pozios, MD, Jorge Gonzales, MD, Yalda Soleimanifard, MD, Sanjay Sivalokanathan, MD, Diego Montoya-Cerrillo, MD, Styliani Vakrou, MD, Ihab Kamel, MD, Wilfredo Mormontoy-Laurel, MD, Ketty Dolores-Cerna, MD, Jacsel Suarez, MD, Sergio Perez-Melo, MD, David A. Bluemke, MD, Theodore P. Abraham, MD, Stefan L. Zimmerman, MD, M. Roselle Abraham, MD
Publikováno v:
Journal of Arrhythmia, Vol 33, Iss 3, Pp 201-207 (2017)
Background: Hypertrophic cardiomyopathy (HCM) is characterized by myocyte hypertrophy, disarray, fibrosis, and increased risk for ventricular arrhythmias. Increased QT dispersion has been reported in patients with HCM, but the underlying mechanisms h
Externí odkaz:
https://doaj.org/article/81772456e8c942c58bbd47cc9b0e3812
Publikováno v:
Arquivos Brasileiros de Cardiologia
Externí odkaz:
https://doaj.org/article/a7989851b31c4c4c86434e63ac1037b4
Publikováno v:
Arquivos Brasileiros de Cardiologia
Reply Sudden cardiac death (SCD) is considered the most dramatic complication of hypertrophic cardiomyopathy (HCM) with an estimated annual incidence of 0.5–1%. Over the years, the ACC/AHA and the ESC have published consensus guidelines providing d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41878e951c097816a0c5f389fd34238e
https://doi.org/10.36660/abc.20201339
https://doi.org/10.36660/abc.20201339
Autor:
Maria Nana, John N. Nanas, Chris J. Kapelios, Ioannis Nanas, Styliani Vakrou, Michael J. Bonios, Emmeleia Nana-Leventaki
Publikováno v:
Hellenic Journal of Cardiology, Vol 61, Iss 4, Pp 256-261 (2020)
Objective Cardiosphere-derived cells (CDCs) have been shown to reduce infarct size after myocardial infarction (MI). In the present study we investigated the safety and efficacy of global intracoronary administration (GIA) of CDCs or CDC-conditioned
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51a74de0de496c92827bef9acdd71122
http://www.sciencedirect.com/science/article/pii/S1109966618305645
http://www.sciencedirect.com/science/article/pii/S1109966618305645