Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Styliani Goulopoulou"'
Autor:
Steve Mabry, E. Nicole Wilson, Jessica L. Bradshaw, Jennifer J. Gardner, Oluwadarasimi Fadeyibi, Edward Vera, Oluwatobiloba Osikoya, Spencer C. Cushen, Dimitrios Karamichos, Styliani Goulopoulou, Rebecca L. Cunningham
Publikováno v:
Biology of Sex Differences, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Background Gestational sleep apnea is a hypoxic sleep disorder that affects 8–26% of pregnancies and increases the risk for central nervous system dysfunction in offspring. Specifically, there are sex differences in the sensitivity of the
Externí odkaz:
https://doaj.org/article/968360606c554d50be2e2734069c0787
Autor:
E. Nicole Wilson, Steve Mabry, Jessica L. Bradshaw, Jennifer J. Gardner, Nataliya Rybalchenko, Rachel Engelland, Oluwadarasimi Fadeyibi, Oluwatobiloba Osikoya, Spencer C. Cushen, Styliani Goulopoulou, Rebecca L. Cunningham
Publikováno v:
Biology of Sex Differences, Vol 13, Iss 1, Pp 1-21 (2022)
Highlights Brain maturation of the nigrostriatal pathway is sex- and age- dependent. Exposure to hypoxia in late pregnancy impacts brain maturation of the nigrostriatal pathway that can be observed during puberty and young adulthood. Gestational hypo
Externí odkaz:
https://doaj.org/article/3011126ba3b94594ab276b7b142b987b
Autor:
Spencer C. Cushen, Contessa A. Ricci, Jessica L. Bradshaw, Talisa Silzer, Alexandra Blessing, Jie Sun, Zhengyang Zhou, Sabrina M. Scroggins, Mark K. Santillan, Donna A. Santillan, Nicole R. Phillips, Styliani Goulopoulou
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 2 (2022)
Background Circulating cell‐free mitochondrial DNA (ccf‐mtDNA) is a damage‐associated molecular pattern that reflects cell stress responses and tissue damage, but little is known about ccf‐mtDNA in preeclampsia. The main objectives of this st
Externí odkaz:
https://doaj.org/article/d2f88f59777f410da14d9d74213d5dca
Publikováno v:
International Journal of Pediatrics, Vol 2010 (2010)
Externí odkaz:
https://doaj.org/article/4794336f776d416bb72c57b98c945158
Autor:
Oluwatobiloba Osikoya, Spencer C. Cushen, Jennifer J. Gardner, Megan M. Raetz, Bhavani Nagarajan, Sangram Raut, Styliani Goulopoulou
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 323:H577-H584
Perivascular adipose tissue (PVAT) is distinct from other adipose depots, as it has differential gene and protein profiles and vasoactive functions. We have shown that pregnancy affects the morphology of PVAT surrounding the uterine arteries (utPVAT)
Autor:
Contessa A. Ricci, Danielle M. Reid, Jie Sun, Donna A. Santillan, Mark K. Santillan, Nicole R. Phillips, Styliani Goulopoulou
Publikováno v:
Physiological Genomics.
Mitochondrial dysfunction has been implicated in pregnancy-induced hypertension (PIH). The role of mitochondrial gene dysregulation in PIH, and consequences for maternal-fetal interactions, remain elusive. Here, we investigated mitochondrial gene exp
Autor:
Selina Tucker, Cooper Warne, Salman Essajee, Styliani Goulopoulou, Gregory Dick, Johnathan Tune
Publikováno v:
Physiology. 38
Thromboxane A2 (TxA2) is a potent coronary vasoconstrictor that has been implicated in promoting decreases in myocardial perfusion in a variety of (patho)-physiologic conditions. S18886 is a promising orally-active TxA2 receptor antagonist currently
Oxidative stress induces non-apoptotic cell death and release of placental derived mitochondrial DNA
Autor:
Jennifer Gardner, Spencer Cushen, Jessica Bradshaw, Isabelle Garlotte, Zhengyang Zhou, Nicole Phillips, Styliani Goulopoulou
Publikováno v:
Physiology. 38
Introduction: The placenta, a metabolically active tissue, forms a critical interface between the developing fetus and mother. Stressors such as oxidative stress contribute to placental inflammation, cell death, and release of proinflammatory factors
Autor:
Jessica Bradshaw, Jennifer Gardner, Selina Tucker, Elizabeth Wilson, Steve Mabry, Rebecca Cunningham, Styliani Goulopoulou
Publikováno v:
Physiology. 38
Introduction: Healthy pregnancy is associated with re-organization of maternal cognitive function that persists through the early postpartum period. In addition, pregnancy is a state of physiological inflammation and oxidative stress that results fro
Autor:
Jessica L. Bradshaw, Spencer C. Cushen, Contessa A. Ricci, Selina M. Tucker, Jennifer J. Gardner, Joel T. Little, Oluwatobiloba Osikoya, Styliani Goulopoulou
Publikováno v:
bioRxiv
Bacterial infections and impaired mitochondrial DNA dynamics are associated with adverse pregnancy outcomes. Unmethylated cytosine-guanine dinucleotide (CpG) motifs are common in bacterial and mitochondrial DNA and act as potent immunostimulators. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acfd04b9b4cbd772a9fde761c3ead5d7
https://europepmc.org/articles/PMC10055100/
https://europepmc.org/articles/PMC10055100/