Výsledky vyhledávání - "Stutts, M. J."

Akademický článek

Chemical Modulation of Alveolar Epithelial Permeability

Autor: Gatzy, J. T., Stutts, M. J.

Publikováno v: Environmental Health Perspectives, 1980 Apr 01. 35, 13-20.

Externí odkaz: https://www.jstor.org/stable/3428969

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Status of Fluid and Electrolyte Absorption in Cystic Fibrosis

Autor: Reddy, M. M., Stutts, M. J.

Salt and fluid absorption is a shared function of many of the body’s epithelia, but its use is highly adapted to the varied physiological roles of epithelia-lined organs. These functions vary from control of hydration of outward-facing epithelial s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5662046239f44cff1a2831059739c92a

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Molecular basis for pH-dependent mucosal dehydration in cystic fibrosis airways

Autor: Hobbs, C. A., Coakley, R. D., Clunes, L. A., Tripathy, A., Garland, A. L., Tan, C. D., Tarran, R., Bencharit, S., Redinbo, M. R., Gilmore, R. C., Stutts, M. J., Betts, L., Walton, W. G.

Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, which codes for a chloride/bicarbonate channel whose absence leads to dehydration and acidification of CF airways. A contributing fact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ff2299fdeb71663a3c7fbb03d7f7e762

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SPLUNC1 regulates airway surface liquid volume by protecting ENaC from proteolytic cleavage

Autor: Stutts, M. J., Tarran, R., Garcia-Caballero, A., Donaldson, S. H., Rasmussen, J. E., Watson, M. J., Olsen, J. C., Gaillard, E.

Many epithelia, including the superficial epithelia of the airways, are thought to secrete “volume sensors,” which regulate the volume of the mucosal lining fluid. The epithelial Na+ channel (ENaC) is often the rate limiting factor in fluid absor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f129f909825af1055c67f3325cfa358d

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Functional consequences of heterologous expression of the cystic fibrosis transmembrane conductance regulator in fibroblasts

Autor: Gatzy, J T, Gabriel, S E, Olsen, J C, Boucher, R C, Stutts, M J, Price, E M, O'Connell, T L

We studied the consequences of cystic fibrosis transmembrane conductance regulator (CFTR) expression in NIH-3T3 fibroblasts as a model for the effects of virally transduced CFTR expression in non-epithelial cells. Fibroblasts were infected with a ret

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::af91071652cf33813bec55a7adef580e

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Regulation of Cl- channels in normal and cystic fibrosis airway epithelial cells by extracellular ATP

Autor: Fullton, J. M., Mason, S. J., Boucher, R. C., Clarke, L. L., Stutts, M. J., Chinet, T. C.

The rate of Cl- secretion by human airway epithelium is determined, in part, by apical cell membrane Cl- conductance. In cystic fibrosis airway epithelia, defective regulation of Cl- conductance decreases the capability to secrete Cl-. Here we report

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::288a334a8b930637c561e8863150e8f9

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