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ITAS: Integrated Transcript Annotation for Small RNA.

Autor: Stupnikov, Alexey^1,2 (AUTHOR) aleksej.stupnikov@phystech.edu, Bezuglov, Vitaly^3,4 (AUTHOR) vanya.skakov@yandex.ru, Skakov, Ivan⁴ (AUTHOR), Shtratnikova, Victoria³ (AUTHOR) vtosha@yandex.ru, Pilsner, J. Richard⁵ (AUTHOR) rpilsner@wayne.edu, Suvorov, Alexander^3,6 (AUTHOR) asuvorov@schoolph.umass.edu, Sergeyev, Oleg³ (AUTHOR) aleksej.stupnikov@phystech.edu

Publikováno v: Non-Coding RNA. Jun2022, Vol. 8 Issue 3, p30-N.PAG. 16p.

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Impact of Variable RNA-Sequencing Depth on Gene Expression Signatures and Target Compound Robustness : Case Study Examining Brain Tumor (Glioma) Disease Progression

Autor: Stupnikov, Alexey, O'Reilly, Paul G, McInerney, Caitriona E, Roddy, Aideen C, Dunne, Philip D, Gilmore, Alan, Ellis, Hayley P, Flannery, Tom, Healy, Estelle, McIntosh, Stuart A, Savage, Kienan, Kurian, Kathreena M, Emmert-Streib, Frank, Prise, Kevin M, Salto-Tellez, Manuel, McArt, Darragh G

Publikováno v: JCO precision oncology
Stupnikov, A, O’Reilly, P G, McInerney, C, Roddy, A, Dunne, P, Gilmore, A, Ellis, H P, Flannery, T, Healy, E, McIntosh, S, Savage, K, Kurian, K M, Emmert-Streib, F, Prise, K, Salto-Tellez, M & McArt, D 2018, ' Impact of Variable RNA-Sequencing Depth on Gene Expression Signatures and Target Compound Robustness: Case Study Examining Brain Tumor (Glioma) Disease Progression ', JCO Precision Oncology, pp. 1-16 . https://doi.org/10.1200/PO.18.00014
Stupnikov, A, O'Reilly, P G, McInerney, C E, Roddy, A C, Dunne, P D, Gilmore, A, Ellis, H P, Flannery, T, Healy, E, McIntosh, S A, Savage, K, Kurian, K M, Emmert-Streib, F, Prise, K M, Salto-Tellez, M & McArt, D G 2018, ' Impact of Variable RNA-Sequencing Depth on Gene Expression Signatures and Target Compound Robustness : Case Study Examining Brain Tumor (Glioma) Disease Progression ', JCO Precision Oncology, vol. 2, 14 . https://doi.org/10.1200/PO.18.00014

PurposeGene expression profiling can uncover biologic mechanisms underlying disease and is important in drug development. RNA sequencing (RNA-seq) is routinely used to assess gene expression, but costs remain high. Sample multiplexing reduces RNA-seq

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::fcdd2c6f5eb7922a55c20c72d6823102
https://trepo.tuni.fi/handle/10024/126806

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