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Influence of insulin sensitivity and the TaqIB cholesteryl ester transfer protein gene polymorphism on plasma lecithin: Cholesterol acyltransferase and lipid transfer protein activities and their response to hyperinsulinaemia in nondiabetic men

Autor: Riemens, SC, Van Tol, A, Stulp, BK, Dullaart, RPF

Publikováno v: Journal of Lipid Research, 42(8), 1467-1474. AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC

Lecithin:cholesteryl acyltransferase (LCAT), cholesteryl ester transfer protein (CETP), phospholipid transfer protein (PLTP), and lipoprotein lipases are involved in high density lipoprotein (HDL) metabolism. We evaluated the influence of insulin sen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::dbf99ac77208c1fb3921fb78f40ae7b3
https://research.rug.nl/en/publications/3559d910-6f6a-4728-8489-56f8a7459238

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High-density lipoprotein cholesterol is related to the TaqIB cholesteryl ester transfer protein gene polymorphism and smoking, but not to moderate alcohol consumption in insulin-dependent diabetic men

Autor: Dullaart, RPF, Beusekamp, BJ, Riemens, SC, Hoogenberg, K, Stulp, BK, Van Tol, A, Sluiter, WJ

Publikováno v: Scandinavian Journal of Clinical & Laboratory Investigation, 58(3), 251-258. Taylor & Francis Ltd

In non-diabetic subjects, the high-density lipoprotein (HDL) cholesterol level is increased by alcohol and decreased by smoking. The biallelic B1B2 polymorphism of the cholesteryl ester transfer protein (CETP) gene is a genetic determinant of HDL cho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::ab44af87ef6e3e72ef28b8678c936c9d
https://research.rug.nl/en/publications/b8ce82a0-adf0-4ef3-b8c4-e888c006165d

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Cholesteryl ester transfer protein gene polymorphism is a determinant of HDL cholesterol and of the lipoprotein response to a lipid-lowering diet in type 1 diabetes

Autor: Dullaart, RPF, Hoogenberg, K, Riemens, SC, Groener, JEM (Johanna), Tol, Aad, Sluiter, Wim, Stulp, BK

Publikováno v: Diabetes, 46(12), 2082-2087. AMER DIABETES ASSOC
Diabetes, 46, 2082-2087. American Diabetes Association Inc.

The TaqIB cholesteryl ester transfer protein (CETP) gene polymorphism (B1B2) is a determinant of HDL cholesterol in nondiabetic populations. Remarkably, this gene effect appears to be modified by environmental factors. We evaluated the effect of this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c79f01833b4a7c6af8c9df9eebba5890
https://research.rug.nl/en/publications/f2a28852-fa67-49f0-9325-cd14f979f15f

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INTRODUCTION OF A STABILIZING 10-RESIDUE BETA-HAIRPIN IN BACILLUS-SUBTILIS NEUTRAL PROTEASE

Autor: EIJSINK, VGH, VRIEND, G, VANDENBURG, B, VANDERZEE, [No Value], VELTMAN, OR, STULP, BK, VENEMA, G

Publikováno v: Protein Engineering, 5(2), 157-163

A 10 residue beta-hairpin, which is characteristic of thermostable Bacillus neutral proteases, was engineered into the thermolabile neutral protease of Bacillus subtilis. The recipient enzyme remained fully active after introduction of the loop. Howe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::8c66c1f393444cb5c43044ec338b2878
https://research.rug.nl/en/publications/06078fd8-7cf1-4112-897c-47d7a02405df

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A HIGHLY THERMOSTABLE NEUTRAL PROTEASE FROM BACILLUS-CALDOLYTICUS - CLONING AND EXPRESSION OF THE GENE IN BACILLUS-SUBTILIS AND CHARACTERIZATION OF THE GENE-PRODUCT

Autor: VANDENBURG, B, ENEQUIST, HG, VANDERHAAR, ME, EIJSINK, VGH, STULP, BK, VENEMA, G

Publikováno v: Journal of Bacteriology, 173(13), 4107-4115. AMER SOC MICROBIOLOGY

By using a gene library of Bacillus caldolyticus constructed in phage lambda EMBL12 and selecting for proteolytically active phages on plates supplemented with 0.8% skim milk, chromosomal B. caldolyticus DNA fragments that specified proteolytic activ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::93cdd2776ed0783820cfb29bc272fc97
https://research.rug.nl/en/publications/31b43bf8-10f0-4896-bb20-29bc99197a2b

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