Investigating neurodegeneration in a Drosophila model of tauopathy

Autor: Stubbs, Katy

Axonal degeneration occurring in disease is thought to be similar to that occurring after acute injury, known as Wallerian degeneration. Wallerian degeneration is an active process that can be delayed by the expression of the slow Wallerian degenerat

Externí odkaz: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.690189

Tau-mediated axonal degeneration is prevented by activation of the Wld ^S pathway.

Autor: Stubbs K; School of Biological Sciences, Faculty of Environment and Life Sciences, University of Southampton, Highfield Campus, Southampton, SO17 1BJ, UK., Batchelor B; School of Biological Sciences, Faculty of Environment and Life Sciences, University of Southampton, Highfield Campus, Southampton, SO17 1BJ, UK., Sivanantharajah L; School of Biological Sciences, Bangor University, Bangor LL57 2UW, UK., Sealey M; School of Biological Sciences, Faculty of Environment and Life Sciences, University of Southampton, Highfield Campus, Southampton, SO17 1BJ, UK., Ramirez-Moreno M; School of Biological Sciences, Faculty of Environment and Life Sciences, University of Southampton, Highfield Campus, Southampton, SO17 1BJ, UK., Ruiz E; School of Biological Sciences, Faculty of Environment and Life Sciences, University of Southampton, Highfield Campus, Southampton, SO17 1BJ, UK., Richardson B; School of Biological Sciences, Faculty of Environment and Life Sciences, University of Southampton, Highfield Campus, Southampton, SO17 1BJ, UK., Perry VH; School of Biological Sciences, Faculty of Environment and Life Sciences, University of Southampton, Highfield Campus, Southampton, SO17 1BJ, UK., Newman TA; Clinical and Experimental Science, Faculty of Medicine, University of Southampton, Highfield Campus, Southampton SO17 1BJ, UK., Mudher A; School of Biological Sciences, Faculty of Environment and Life Sciences, University of Southampton, Highfield Campus, Southampton, SO17 1BJ, UK.

Publikováno v: Brain communications [Brain Commun] 2023 Mar 09; Vol. 5 (2), pp. fcad052. Date of Electronic Publication: 2023 Mar 09 (Print Publication: 2023).