Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Stubbington MJT"'
Autor:
Johan Henriksson, Sarah A. Teichmann, Mirjana Efremova, Miquel Vento-Tormo, Krzysztof Polanski, Margherita Y. Turco, Kerstin B. Meyer, Gavin J. Wright, Jong-Eun Park, Andrew Filby, Muzlifah Haniffa, Rebecca Payne, Angela Goncalves, Zou A, Laura Wood, Roser Vento-Tormo, Ashley Moffett, Steve Lisgo, Emily Stephenson, Rachel A. Botting, Stubbington Mjt
SummaryDuring the early weeks of human pregnancy, the fetal placenta implants into the uterine mucosa (decidua) where placental trophoblast cells intermingle and communicate with maternal cells. Here, we profile transcriptomes of ∼50,000 single cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc3f546e50a05495a1d8e30140d100b6
Autor:
Regev, A, Teichmann, SA, Lander, ES, Amit, I, Benoist, C, Birney, E, Bodenmiller, B, Campbell, PJ, Carninci, P, Clatworthy, M, Clevers, H, Deplancke, B, Dunham, I, Eberwine, J, Eils, R, Enard, W, Farmer, A, Fugger, L, Göttgens, B, Hacohen, N, Haniffa, M, Hemberg, M, Kim, SK, Klenerman, P, Kriegstein, A, Lein, E, Linnarsson, S, Lundberg, E, Lundeberg, J, Majumder, P, Marioni, JC, Merad, M, Mhlanga, M, Nawijn, M, Netea, M, Nolan, G, Pe'er, D, Phillipakis, A, Ponting, CP, Quake, SR, Reik, W, Rozenblatt-Rosen, O, Sanes, JR, Satija, R, Schumacher, TN, Shalek, AK, Shapiro, E, Sharma, P, Shin, JW, Stegle, O, Stratton, MR, Stubbington, MJT, Theis, FJ, Uhlen, M, van Oudenaarden, A, Wagner, A, Watt, FM, Weissman, JS, Wold, BJ, Xavier, RJ, Yosef, N
The recent advent of methods for high-throughput single-cell molecular profiling has catalyzed a growing sense in the scientific community that the time is ripe to complete the 150-year-old effort to identify all cell types in the human body. The Hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f30a0e14d984ce1edece507acc572dcd
https://ora.ox.ac.uk/objects/uuid:4f6fd5b8-a1d7-48ba-8391-2877bb870300
https://ora.ox.ac.uk/objects/uuid:4f6fd5b8-a1d7-48ba-8391-2877bb870300
Autor:
Hegazy, AN, West, NR, Stubbington, MJT, Wendt, E, Suijker, KIM, Datsi, A, This, S, Danne, C, Campion, S, Duncan, SH, Owens, BMJ, Uhlig, HH, McMichael, A, Bergthaler, A, Teichmann, SA, Keshav, S, Powrie, F
Publikováno v:
Gastroenterology. 153(5)
Background & Aims Interactions between commensal microbes and the immune system are tightly regulated and maintain intestinal homeostasis, but little is known about these interactions in humans. We investigated responses of human CD4+T cellsto the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::77be831271cfce0610d56bfe5fb495bf
http://ora.ox.ac.uk/objects/uuid:
http://ora.ox.ac.uk/objects/uuid:
Autor:
Martinez-Jimenez, CP, Eling, N, Chen, H-C, Vallejos, CA, Kolodziejczyk, AA, Connor, F, Stojic, L, Rayner, TF, Stubbington, MJT, Teichmann, SA, de la Roche, M, Marioni, JC, Odom, DT
Aging is characterized by progressive loss of physiological and cellular functions, but the molecular basis of this decline remains unclear. We explored how aging affects transcriptional dynamics using single-cell RNA sequencing of unstimulated and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______109::6e8439b080469cd99dc18e3d51dadb39
https://www.repository.cam.ac.uk/handle/1810/264279
https://www.repository.cam.ac.uk/handle/1810/264279
Autor:
Oliver Stegle, Kylie R. James, Ashraful Haque, William R. Heath, Tapio Lönnberg, Ruddy Montandon, Daniel Fernandez-Ruiz, Otzen Bagger F, Max Zwiessele, Stubbington Mjt, Svensson, Soon Msf, Oliver Billker, Lily Fogg, Sarah A. Teichmann, Fernando Souza-Fonseca-Guimaraes, Ismail Sebina, Neil D. Lawrence
Differentiation of naïve CD4+ T cells into functionally distinct T helper subsets is crucial for the orchestration of immune responses. Due to multiple levels of heterogeneity and multiple overlapping transcriptional programs in differentiating T ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a660a83bfac50d4ee2a2b6bcc3eaf3
https://doi.org/10.1101/074971
https://doi.org/10.1101/074971
Autor:
Carmona, SJ, Teichmann, SA, Ferreira, L, Macaulay, IC, Stubbington, MJT, Cvejic, A, Gfeller, D
The immune system of vertebrate species consists of many different cell types that have distinct functional roles and are subject to different evolutionary pressures. Here, we first analyzed conservation of genes specific for all major immune cell ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26bb23ee184f321cedfc84d37ebee751
Autor:
Martinez-Jimenez, CP, Eling, N, Chen, H-C, Vallejos, CA, Kolodziejczyk, AA, Connor, F, Stojic, L, Rayner, TF, Stubbington, MJT, Teichmann, SA, De La Roche, M, Marioni, JC, Odom, DT
Aging is characterized by progressive loss of physiological and cellular functions, but the molecular basis of this decline remains unclear. We explored how aging affects transcriptional dynamics using single-cell RNA sequencing of unstimulated and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29047b5d9ddc4e80cd30646afd61e436
Autor:
Hurtado J; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for Viral Systems Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; Scripps Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA., Rogers TF; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Division of Infectious Diseases, Department of Medicine, University of California, San Diego, La Jolla, CA 92037, USA., Jaffe DB; 10x Genomics, Inc., 6230 Stoneridge Mall Road, Pleasanton, CA 94588, USA., Adams BA; 10x Genomics, Inc., 6230 Stoneridge Mall Road, Pleasanton, CA 94588, USA., Bangaru S; Department of Integrative Structural and Computational Biology, Scripps Research, La Jolla, CA 92037, USA., Garcia E; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA., Capozzola T; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for Viral Systems Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; Scripps Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA., Messmer T; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for Viral Systems Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; Scripps Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA., Sharma P; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for Viral Systems Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; Scripps Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA., Song G; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for Viral Systems Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; Scripps Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA., Beutler N; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA., He W; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for Viral Systems Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; Scripps Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA., Dueker K; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for Viral Systems Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; Scripps Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA., Musharrafieh R; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for Viral Systems Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; Scripps Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA., Burbach S; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for Viral Systems Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; Scripps Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA., Truong A; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for Viral Systems Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; Scripps Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA., Stubbington MJT; 10x Genomics, Inc., 6230 Stoneridge Mall Road, Pleasanton, CA 94588, USA., Burton DR; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Scripps Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA; Ragon Institute of MGH, Harvard and MIT, Cambridge, MA 02139, USA., Andrabi R; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for Viral Systems Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; Scripps Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA., Ward AB; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Scripps Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA; Department of Integrative Structural and Computational Biology, Scripps Research, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA., McDonnell WJ; 10x Genomics, Inc., 6230 Stoneridge Mall Road, Pleasanton, CA 94588, USA. Electronic address: wyatt@infinimmune.com., Briney B; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for Viral Systems Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; Scripps Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA; Multi-Omics Vaccine Evaluation Consortium, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address: briney@scripps.edu.
Publikováno v:
Cell reports [Cell Rep] 2024 Jun 25; Vol. 43 (6), pp. 114307. Date of Electronic Publication: 2024 Jun 05.
Autor:
Mielczarek O; Nuclear Dynamics Programme, Babraham Institute, Babraham Research Campus, Cambridge CB22 3AT, UK., Rogers CH; Nuclear Dynamics Programme, Babraham Institute, Babraham Research Campus, Cambridge CB22 3AT, UK; Immunology Programme, Babraham Institute, Babraham Research Campus, Cambridge CB22 3AT, UK., Zhan Y; Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, 4058 Basel, Switzerland., Matheson LS; Nuclear Dynamics Programme, Babraham Institute, Babraham Research Campus, Cambridge CB22 3AT, UK; Immunology Programme, Babraham Institute, Babraham Research Campus, Cambridge CB22 3AT, UK., Stubbington MJT; Nuclear Dynamics Programme, Babraham Institute, Babraham Research Campus, Cambridge CB22 3AT, UK., Schoenfelder S; Nuclear Dynamics Programme, Babraham Institute, Babraham Research Campus, Cambridge CB22 3AT, UK., Bolland DJ; Nuclear Dynamics Programme, Babraham Institute, Babraham Research Campus, Cambridge CB22 3AT, UK; Immunology Programme, Babraham Institute, Babraham Research Campus, Cambridge CB22 3AT, UK., Javierre BM; Nuclear Dynamics Programme, Babraham Institute, Babraham Research Campus, Cambridge CB22 3AT, UK., Wingett SW; Bioinformatics Group, Babraham Institute, Babraham Research Campus, Cambridge CB22 3AT, UK., Várnai C; Nuclear Dynamics Programme, Babraham Institute, Babraham Research Campus, Cambridge CB22 3AT, UK., Segonds-Pichon A; Bioinformatics Group, Babraham Institute, Babraham Research Campus, Cambridge CB22 3AT, UK., Conn SJ; Flinders Health and Medical Research Institute, College of Medicine and Public Health, Flinders University, Bedford Park, SA 5042, Australia., Krueger F; Bioinformatics Group, Babraham Institute, Babraham Research Campus, Cambridge CB22 3AT, UK., Andrews S; Bioinformatics Group, Babraham Institute, Babraham Research Campus, Cambridge CB22 3AT, UK., Fraser P; Nuclear Dynamics Programme, Babraham Institute, Babraham Research Campus, Cambridge CB22 3AT, UK., Giorgetti L; Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, 4058 Basel, Switzerland., Corcoran AE; Nuclear Dynamics Programme, Babraham Institute, Babraham Research Campus, Cambridge CB22 3AT, UK; Immunology Programme, Babraham Institute, Babraham Research Campus, Cambridge CB22 3AT, UK. Electronic address: anne.corcoran@babraham.ac.uk.
Publikováno v:
Cell reports [Cell Rep] 2023 Sep 26; Vol. 42 (9), pp. 113074. Date of Electronic Publication: 2023 Sep 06.
Autor:
Hurtado J; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.; Center for Viral Systems Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.; Scripps Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA., Rogers TF; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.; Division of Infectious Diseases, Department of Medicine, University of California, San Diego, La Jolla, CA 92037, USA., Jaffe DB; 10x Genomics, Inc. 6230 Stoneridge Mall Road, Pleasanton, CA 94588, USA., Adams BA; 10x Genomics, Inc. 6230 Stoneridge Mall Road, Pleasanton, CA 94588, USA., Bangaru S; Department of Integrative Structural and Computational Biology, Scripps Research, La Jolla, CA 92037, USA., Garcia E; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA., Capozzola T; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.; Center for Viral Systems Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.; Scripps Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA., Messmer T; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.; Center for Viral Systems Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.; Scripps Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA., Sharma P; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.; Center for Viral Systems Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.; Scripps Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA., Song G; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.; Center for Viral Systems Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.; Scripps Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA., Beutler N; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA., He W; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.; Center for Viral Systems Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.; Scripps Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA., Dueker K; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.; Center for Viral Systems Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.; Scripps Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA., Musharrafieh R; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.; Center for Viral Systems Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.; Scripps Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA., Stubbington MJT; 10x Genomics, Inc. 6230 Stoneridge Mall Road, Pleasanton, CA 94588, USA., Burton DR; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.; Scripps Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA.; Ragon Institute of MGH, Harvard and MIT, Cambridge, MA 02139, USA., Andrabi R; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.; Center for Viral Systems Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.; Scripps Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA., Ward AB; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.; Scripps Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA.; Department of Integrative Structural and Computational Biology, Scripps Research, La Jolla, CA 92037, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA., McDonnell WJ; 10x Genomics, Inc. 6230 Stoneridge Mall Road, Pleasanton, CA 94588, USA., Briney B; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.; Center for Viral Systems Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.; Scripps Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA.
Publikováno v:
BioRxiv : the preprint server for biology [bioRxiv] 2023 Mar 31. Date of Electronic Publication: 2023 Mar 31.