De novo assembly and annotation of the singing mouse genome

Autor: Samantha K. Smith, Paul W. Frazel, Alireza Khodadadi-Jamayran, Paul Zappile, Christian Marier, Mariam Okhovat, Stuart Brown, Michael A. Long, Adriana Heguy, Steven M. Phelps

Publikováno v: BMC Genomics, Vol 24, Iss 1, Pp 1-12 (2023)

Abstract Background Developing genomic resources for a diverse range of species is an important step towards understanding the mechanisms underlying complex traits. Specifically, organisms that exhibit unique and accessible phenotypes-of-interest all

Externí odkaz: https://doaj.org/article/798eb7a09956465eb3041f88f28ffb5e

Case control study comparing the HPV genome in patients with oral cavity squamous cell carcinoma to normal patients using metagenomic shotgun sequencing

Autor: Ian Ganly, Zhiheng Pei, Yuhan Hao, Yingfei Ma, Matthew Rosenthal, Zhenglin Wu, Jocelyn Migliacci, Bin Huang, Nora Katabi, Wenzhi Tseng, Stuart Brown, Yi-Wei Tang, Liying Yang

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)

Abstract The aim of this study was to carry out a case control study comparing the HPV genome in patients with oral cavity squamous cell carcinoma (OC-SCC) to normal patients using metagenomic shotgun sequencing. We recruited 50 OC-SCC cases which we

Externí odkaz: https://doaj.org/article/28c3bdf55796428aa654af7e652236f0

Wild gardening as a sustainable intensification strategy in northwest Cambodian smallholder systems

Autor: Sarah Eissler, David Ader, Sovanneary Huot, Stuart Brown, Ricky Bates, Thomas Gill

Publikováno v: Journal of Agriculture, Food Systems, and Community Development, Vol 10, Iss 3 (2021)

Within the last decade, Sustainable Intensification (SI) has emerged as a strategy to respond to future food security challenges. It incorporates increased food production without the cultivation of more land while incurring no net environmental cost

Externí odkaz: https://doaj.org/article/568073f0b58442c08f576c67683615d9

Faster ocean warming threatens richest areas of marine biodiversity

Autor: Eline Lorenzen, Jorge García Molinos, Damien Fordham, Stuart Brown, Camille Mellin

Publikováno v: Brown, S C, Mellin, C, García Molinos, J, Lorenzen, E D & Fordham, D A 2022, ' Faster ocean warming threatens richest areas of marine biodiversity ', Global Change Biology, vol. 28, no. 19, pp. 5849-5858 . https://doi.org/10.1111/gcb.16328

The vulnerability of marine biodiversity to accelerated rates of climatic change is poorly understood. By developing a new method for identifying extreme oceanic warming events during Earth's most recent deglaciation, and comparing these to 21st cent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::134e8a5231763fcb60c392fe04b1212d
https://doi.org/10.1111/gcb.16328

Protective Effect of Nasal Colonisation with ∆cps/piaA and ∆cps/proABCStreptococcus pneumoniae Strains against Recolonisation and Invasive Infection

Autor: Elisa Ramos-Sevillano, Giuseppe Ercoli, José Afonso Guerra-Assunção, Philip Felgner, Rafael Ramiro de Assis, Rie Nakajima, David Goldblatt, Kevin Kweku Adjei Tetteh, Robert Simon Heyderman, Stephen Brian Gordon, Daniela Mulari Ferreria, Jeremy Stuart Brown

Publikováno v: Vaccines, Vol 9, Iss 3, p 261 (2021)

Rationale: Nasopharyngeal administration of live virulence-attenuated Streptococcus pneumoniae strains is a potential novel preventative strategy. One target for creating reduced virulence S. pneumoniae strains is the capsule, but loss of the capsule

Externí odkaz: https://doaj.org/article/49a7fad3616a46729a4e6aada6193bc7