Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Stuart S. Adamson"'
Publikováno v:
Translational Medicine of Aging, Vol 1, Iss , Pp 18-23 (2017)
Alcohol is one of the most widely encountered drugs in the world and is credited with a wealth of health interactions. Light to moderate regular consumption (14–28 g daily) can promote heart health, protect against Type II diabetes, and likely exte
Externí odkaz:
https://doaj.org/article/792fdecc05324f228175df9f1f7ccb89
Autor:
Ivana Semova, Amy E. Levenson, Joanna Krawczyk, Kevin Bullock, Mary E. Gearing, Alisha V. Ling, Kathryn A. Williams, Ji Miao, Stuart S. Adamson, Dong-Ju Shin, Satyapal Chahar, Mark J. Graham, Rosanne M. Crooke, Lee R. Hagey, David Vicent, Sarah D. de Ferranti, Srividya Kidambi, Clary B. Clish, Sudha B. Biddinger
Publikováno v:
Circulation. 145:969-982
Background: The risk of cardiovascular disease in type 1 diabetes remains extremely high, despite marked advances in blood glucose control and even the widespread use of cholesterol synthesis inhibitors. Thus, a deeper understanding of insulin regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ca2124fc7275eb4933a7048b8e5ef0
https://doi.org/10.1161/circulationaha.120.045373
https://doi.org/10.1161/circulationaha.120.045373
Autor:
Xu Zhang, Cristobal Ibaceta Ibaceta-Gonzalez, Stuart A. Lipton, Stuart S. Adamson, Claudio Hetz, Claudia Duran-Aniotz, Carleen Sabusap, Giovanni Tamburini, Hernan Huerta, Adrian G. Palacios, Kaitlyn Vitangcol, Tomohiro Nakamura, Tim Miedema, Francisca Bermedo, Danilo B. Medinas, S. Pablo Sardi, Felipe Cabral-Miranda, Yannis Gerakis, Alvaro O. Ardiles, Julio Matus, Juan Pablo Henríquez, Gabriela Martínez, Lars Plate, Brian K. Kennedy
Brain ageing is the main risk factor to develop dementia and neurodegenerative diseases, associated with a decay in the buffering capacity of the proteostasis network. We investigated the significance of the unfolded protein response (UPR), a major s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8eaf1474df3730b09b4553264afe5af0
https://doi.org/10.21203/rs.3.rs-83658/v1
https://doi.org/10.21203/rs.3.rs-83658/v1
Autor:
Kaitlyn Vitangcol, Xu Zhang, Giovanni Tamburini, Gabriela Martínez, Yannis Gerakis, Lars Plate, Francisca Bermedo-Garcia, Tomohiro Nakamura, Alvaro Ardilles, Julio Cardenas Cardenas, S. Pablo Sardi, Danilo B. Medinas, Felipe Cabral Miranda, Adrian G. Palacios, Claudia Duran-Aniotz, Juan Pablo Henríquez, Cristobal Ibaceta, Stuart A. Lipton, Carleen Sabusap, Tim Miedema, Stuart S. Adamson, Brian K. Kennedy, Claudio Hetz, Hernan Huerta
Aging is the major risk factor for the development of dementia and neurodegenerative disorders, and the aging brain manifests severe deficits in buffering capacity by the proteostasis network. Accordingly, we investigated the significance of the unfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b4b13d30da3d9174f42e0ab997d7c97
Autor:
Brittany J. Garrett, Dominic J. Withers, Amanda M Bair, Joy A. Wilson, Delana M Miller, Erin M Stewart, Chen-Yu Liao, Sydney S. Anderson, Nicole H. Chicoine, Gabriella Tannady, Charlotte S Kwok, Emmeline C. Academia, Jarrott R. Mayfield, Brian K. Kennedy, Stuart S. Adamson, Yueh-Mei Hsu, Junying Wang
Publikováno v:
Cell Discovery
The mechanistic target of rapamycin (mTOR) signaling pathway plays a central role in aging and a number of different disease states. Rapamycin, which suppresses activity of the mTOR complex 1 (mTORC1), shows preclinical (and sometimes clinical) effic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7770dc559fad04622240caaa20a99d3f
http://hdl.handle.net/10044/1/54238
http://hdl.handle.net/10044/1/54238
Autor:
Crombie EM; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Kim S; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Adamson S; Buck Institute for Research on Aging, Novato, California, USA., Dong H; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Lu TC; Research Center for Healthy Aging, China Medical University, Taichung, Taiwan., Wu Y; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Wu Y; Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Levy Y; Centre of Human and Applied Physiological Sciences, School of Basic and Medical Biosciences, Faculty of Life Sciences & Medicine, King's College, London, UK., Stimple N; Buck Institute for Research on Aging, Novato, California, USA., Lam WMR; Department of Orthopedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Hey HWD; Department of Orthopedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Withers DJ; Metabolic Signalling Group, Medical Research Council London Institute of Medical Sciences (LMS), London, UK.; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, London, UK., Hsu AL; Research Center for Healthy Aging, China Medical University, Taichung, Taiwan.; Institute of Biochemistry and Molecular Biology, National Yang Ming Chiao Tung University, Taipei, Taiwan., Bay BH; Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Ochala J; Centre of Human and Applied Physiological Sciences, School of Basic and Medical Biosciences, Faculty of Life Sciences & Medicine, King's College, London, UK.; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark., Tsai SY; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Healthy Longevity Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Publikováno v:
Journal of cachexia, sarcopenia and muscle [J Cachexia Sarcopenia Muscle] 2023 Feb; Vol. 14 (1), pp. 198-213. Date of Electronic Publication: 2022 Nov 17.
Autor:
Ang SJ; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117593, Singapore.; Healthy Longevity Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117456, Singapore., Crombie EM; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117593, Singapore., Dong H; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117593, Singapore., Tan KT; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117593, Singapore., Hernando A; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117593, Singapore., Yu D; Healthy Longevity Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117456, Singapore.; Electrophysiology Core Facility, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117544, Singapore.; Cardiovascular Diseases Program, National University of Singapore, Singapore, 117599, Singapore., Adamson S; Buck Institute for Research on Aging, Novato, CA, USA., Kim S; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117593, Singapore., Withers DJ; Metabolic Signalling Group, Medical Research Council Clinical Council London Institute of Medical Sciences (LMS), Du Cane Road, London, W12 0NN, UK.; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, Du Cane Road, London, W12 0NN, UK., Huang H; Healthy Longevity Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117456, Singapore.; Electrophysiology Core Facility, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117544, Singapore.; Cardiovascular Diseases Program, National University of Singapore, Singapore, 117599, Singapore., Tsai SY; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117593, Singapore. phsts@nus.edu.sg.; Healthy Longevity Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117456, Singapore. phsts@nus.edu.sg.
Publikováno v:
Nature communications [Nat Commun] 2022 Dec 17; Vol. 13 (1), pp. 7792. Date of Electronic Publication: 2022 Dec 17.
Autor:
Cabral-Miranda F; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile.; Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil., Tamburini G; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile., Martinez G; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile., Ardiles AO; Centro Interdisciplinario de Neurociencia de Valparaíso, Universidad de Valparaiso, Valparaiso, Chile.; Centro de Neurología Traslacional, Escuela de Medicina, Universidad de Valparaíso, Valparaiso, Chile., Medinas DB; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile., Gerakis Y; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile., Hung MD; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile., Vidal R; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.; Center for Integrative Biology, Universidad Mayor, Santiago, Chile., Fuentealba M; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile., Miedema T; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile., Duran-Aniotz C; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile., Diaz J; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile., Ibaceta-Gonzalez C; Centro Interdisciplinario de Neurociencia de Valparaíso, Universidad de Valparaiso, Valparaiso, Chile., Sabusap CM; Departments of Chemistry and Biological Sciences, Vanderbilt University, Nashville, TN, USA., Bermedo-Garcia F; Department of Cell Biology, Center for Advanced Microscopy (CMA BioBio), Universidad de Concepción, Concepción, Chile., Mujica P; Centro de Neurología Traslacional, Escuela de Medicina, Universidad de Valparaíso, Valparaiso, Chile., Adamson S; Buck Institute for Research on Aging, Novato, CA, USA., Vitangcol K; Buck Institute for Research on Aging, Novato, CA, USA., Huerta H; Center for Integrative Biology, Universidad Mayor, Santiago, Chile., Zhang X; Department of Molecular Medicine and Neurodegeneration New Medicines Center, The Scripps Research Institute, La Jolla, CA, USA., Nakamura T; Department of Molecular Medicine and Neurodegeneration New Medicines Center, The Scripps Research Institute, La Jolla, CA, USA., Sardi SP; Rare and Neurological Diseases Therapeutic Area, Sanofi, Framingham, MA, USA., Lipton SA; Department of Molecular Medicine and Neurodegeneration New Medicines Center, The Scripps Research Institute, La Jolla, CA, USA.; Department of Neurosciences, School of Medicine, University of California, San Diego, La Jolla, CA, USA., Kennedy BK; Buck Institute for Research on Aging, Novato, CA, USA.; Healthy Longevity Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore; Centre for Healthy Longevity, National University Health System; Departments of Biochemistry and Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Henriquez JP; Department of Cell Biology, Center for Advanced Microscopy (CMA BioBio), Universidad de Concepción, Concepción, Chile., Cárdenas JC; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Center for Integrative Biology, Universidad Mayor, Santiago, Chile.; Buck Institute for Research on Aging, Novato, CA, USA., Plate L; Departments of Chemistry and Biological Sciences, Vanderbilt University, Nashville, TN, USA., Palacios AG; Centro Interdisciplinario de Neurociencia de Valparaíso, Universidad de Valparaiso, Valparaiso, Chile., Hetz C; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile.; Buck Institute for Research on Aging, Novato, CA, USA.
Publikováno v:
The EMBO journal [EMBO J] 2022 Nov 17; Vol. 41 (22), pp. e111952. Date of Electronic Publication: 2022 Oct 31.
Autor:
Vider J; School of Medical Science and Menzies Health Institute QLD, Griffith University, Gold Coast, Queensland, 4222, Australia.; Systems Biology and Data Science, Menzies Health Institute QLD, Griffith University, Gold Coast, Queensland, 4222, Australia., Croaker A; School of Health and Human Sciences, Southern Cross University, Lismore, NSW, Australia.; Toormina Medical Centre, Toormina, NSW, Australia., Cox AJ; School of Medical Science and Menzies Health Institute QLD, Griffith University, Gold Coast, Queensland, 4222, Australia.; Systems Biology and Data Science, Menzies Health Institute QLD, Griffith University, Gold Coast, Queensland, 4222, Australia., Raymond E; Wesley Medical Research, Auchenflower, QLD, Australia.; Brain Cancer Biobanking Australia, Camperdown, NSW, Australia., Rogers R; Wesley Medical Research, Auchenflower, QLD, Australia., Adamson S; Mid-West Aero Medical, Geraldton, Perth, Australia., Doyle M; Wesley Medical Research, Auchenflower, QLD, Australia., O'Brien B; Sullivan &Nicolaides Pathology, Bowen Hills, QLD, Australia., Cripps AW; Systems Biology and Data Science, Menzies Health Institute QLD, Griffith University, Gold Coast, Queensland, 4222, Australia.; School of Medicine and Menzies Health Institute QLD, Griffith University, Gold Coast, QLD, Australia., West NP; School of Medical Science and Menzies Health Institute QLD, Griffith University, Gold Coast, Queensland, 4222, Australia. n.west@griffith.edu.au.; Systems Biology and Data Science, Menzies Health Institute QLD, Griffith University, Gold Coast, Queensland, 4222, Australia. n.west@griffith.edu.au.
Publikováno v:
Diagnostic pathology [Diagn Pathol] 2020 May 15; Vol. 15 (1), pp. 57. Date of Electronic Publication: 2020 May 15.