Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Stuart S, Levine"'
Autor:
Nick K. Davis, Yok Hian Chionh, Megan E. McBee, Fabian Hia, Duanduan Ma, Liang Cui, Mariam Lucila Sharaf, Weiling Maggie Cai, Watthanachai Jumpathong, Stuart S. Levine, Sylvie Alonso, Peter C. Dedon
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract Mycobacteria adapt to infection stresses by entering a reversible non-replicating persistence (NRP) with slow or no cell growth and broad antimicrobial tolerance. Hypoxia and nutrient deprivation are two well-studied stresses commonly used t
Externí odkaz:
https://doaj.org/article/f8fddf70d57c4a719df9e9dd98168d53
Autor:
Galina Gabriely, Duanduan Ma, Shafiuddin Siddiqui, Linqing Sun, Nathaniel P. Skillin, Hadi Abou-El-Hassan, Thais G. Moreira, Dustin Donnelly, Andre P. da Cunha, Mai Fujiwara, Lena R. Walton, Amee Patel, Rajesh Krishnan, Stuart S. Levine, Brian C. Healy, Rafael M. Rezende, Gopal Murugaiyan, Howard L. Weiner
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103347- (2021)
Summary: Myeloid suppressor cells promote tumor growth by a variety of mechanisms which are not fully characterized. We identified myeloid cells (MCs) expressing the latency-associated peptide (LAP) of TGF-β on their surface and LAPHi MCs that stimu
Externí odkaz:
https://doaj.org/article/cd2b4250e05d4e979dda9bd8430b32ec
Autor:
Zachary T. Herbert, Jamie P. Kershner, Vincent L. Butty, Jyothi Thimmapuram, Sulbha Choudhari, Yuriy O. Alekseyev, Jun Fan, Jessica W. Podnar, Edward Wilcox, Jenny Gipson, Allison Gillaspy, Kristen Jepsen, Sandra Splinter BonDurant, Krystalynne Morris, Maura Berkeley, Ashley LeClerc, Stephen D. Simpson, Gary Sommerville, Leslie Grimmett, Marie Adams, Stuart S. Levine
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-10 (2018)
Abstract Background Ribosomal RNA (rRNA) comprises at least 90% of total RNA extracted from mammalian tissue or cell line samples. Informative transcriptional profiling using massively parallel sequencing technologies requires either enrichment of ma
Externí odkaz:
https://doaj.org/article/5f84f85b08874e36850d23efaeb4633c
Autor:
Shuping Zhang, Alejandra Macias-Garcia, Jacob C Ulirsch, Jason Velazquez, Vincent L Butty, Stuart S Levine, Vijay G Sankaran, Jane-Jane Chen
Publikováno v:
eLife, Vol 8 (2019)
Iron and heme play central roles in the production of red blood cells, but the underlying mechanisms remain incompletely understood. Heme-regulated eIF2α kinase (HRI) controls translation by phosphorylating eIF2α. Here, we investigate the global im
Externí odkaz:
https://doaj.org/article/9c7a78b9c73a4cf8925af57b0da38a26
Publikováno v:
PLoS Genetics, Vol 15, Iss 2, p e1007830 (2019)
The nematode Caenorhabditis elegans has emerged as a genetically tractable animal host in which to study evolutionarily conserved mechanisms of innate immune signaling. We previously showed that the PMK-1 p38 mitogen-activated protein kinase (MAPK) p
Externí odkaz:
https://doaj.org/article/1e1115df8ee444559d564718a0e90c2a
Autor:
Stefan J. Green, Tamas Torok, Jonathan E. Allen, Emiley Eloe-Fadrosh, Scott A. Jackson, Sunny C. Jiang, Stuart S. Levine, Shawn Levy, Lynn M. Schriml, W. Kelley Thomas, Jason M. Wood, Scott W. Tighe
Publikováno v:
Astrobiology.
Molecular biology methods and technologies have advanced substantially over the past decade. These new molecular methods should be incorporated among the standard tools of planetary protection (PP) and could be validated for incorporation by 2026. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5a821c41a3a7f8c8142f71b499f3f9e
https://doi.org/10.1089/ast.2022.0044
https://doi.org/10.1089/ast.2022.0044
Autor:
Angela M Phillips, Luna O Gonzalez, Emmanuel E Nekongo, Anna I Ponomarenko, Sean M McHugh, Vincent L Butty, Stuart S Levine, Yu-Shan Lin, Leonid A Mirny, Matthew D Shoulders
Publikováno v:
eLife, Vol 6 (2017)
Predicting and constraining RNA virus evolution require understanding the molecular factors that define the mutational landscape accessible to these pathogens. RNA viruses typically have high mutation rates, resulting in frequent production of protei
Externí odkaz:
https://doaj.org/article/d0cc390170574171b07951531c6151db
Autor:
Mayinuer Maitituoheti, Alvin Shi, Ming Tang, Li-Lun Ho, Christopher Terranova, Kyriaki Galani, Emily Z. Keung, Caitlin A. Creasy, Manrong Wu, Jiajia Chen, Nana Chen, Anand K. Singh, Apoorvi Chaudhri, Nazanin E. Anvar, Giuseppe Tarantino, Jiekun Yang, Sharmistha Sarkar, Shan Jiang, Jared Malke, Lauren Haydu, Elizabeth Burton, Michael A. Davies, Jeffrey E. Gershenwald, Patrick Hwu, Alexander Lazar, Jaime H. Cheah, Christian K. Soule, Stuart S. Levine, Chantale Bernatchez, Srinivas V. Saladi, David Liu, Jennifer Wargo, Genevieve M. Boland, Manolis Kellis, Kunal Rai
Immune checkpoint blockade (ICB) therapy has improved long-term survival for patients with advanced melanoma. However, there is critical need to identify potential biomarkers of response and actionable strategies to improve response rates. Through ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8eaaf351101ec13c4d6de8f5b3117091
https://doi.org/10.1101/2022.08.31.506051
https://doi.org/10.1101/2022.08.31.506051
Autor:
Michael S. DeMott, Daniel Yim, Sabrina M. Huber, Duanduan Ma, Jo Marie Bacusmo, Peter C. Dedon, Bo Cao, Jennifer Hu, Jieliang Zhou, Sidney Vermeulen, Thomas J. Begley, Valérie de Crécy-Lagard, Nick Davis, Stuart S. Levine
Publikováno v:
Nature biotechnology
Current next-generation RNA-sequencing (RNA-seq) methods do not provide accurate quantification of small RNAs within a sample, due to sequence-dependent biases in capture, ligation and amplification during library preparation. We present a method, ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93b6fb9afeeb2882c471145b651bf46e
https://doi.org/10.1038/s41587-021-00874-y
https://doi.org/10.1038/s41587-021-00874-y
Autor:
Kunal Rai, Mayinuer Maitituoheti, Alvin Shi, Ming Tang, Li-Lun Ho, Firas Youssef Kreidieh, Christopher Terranova, Kyriakitsa Galani, Emily Z. Keung, Caitlin A. Creasy, Manrong Wu, Jiajia Chen, Nana Chen, Anand K. Singh, Apoorvi Chaudhri, Nazanin E. Anvar, Giuseppe Tarrantino, Jiekun Yang, Sharmistha Sarkar, Shan Jiang, Jared Malke, Lauren Haydu, Elizabeth Burton, Michael A. Davies, Jeffrey E. Gershenwald, Patrick Hwu, Alexander Lazar, Jaime H. Cheah, Christian K. Soule, Stuart S. Levine, Chantale Bernatchez, Srinivas V. Saladi, David Liu, Hussein Tawbi, Jennifer Wargo, Genevieve M. Boland, Manolis Kellis
Publikováno v:
Cancer Research. 83:6425-6425
Immune checkpoint blockade (ICB) therapy has improved long-term survival for patients with advanced melanoma. However, there is critical need to identify potential biomarkers of response and actionable strategies to improve response rates. Through ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1372246006bfd333c190c5a08eb4cb57
https://doi.org/10.1158/1538-7445.am2023-6425
https://doi.org/10.1158/1538-7445.am2023-6425