Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Stuart Rudikoff"'
Autor:
James J. Mulé, David M. Jablons, R. P. Nordan, Joe K. McIntosh, Stuart Rudikoff, Steven A. Rosenberg, Michael T. Lotze
Publikováno v:
Annals of the New York Academy of Sciences. 557:572-575
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b1189bba5aab1205b74f19624480016
https://doi.org/10.1111/j.1749-6632.1989.tb24070.x
https://doi.org/10.1111/j.1749-6632.1989.tb24070.x
Autor:
Michael T. Lotze, James J. Mulé, Stuart Rudikoff, David M. Jablons, R. P. Nordan, Joe K. McIntosh
Publikováno v:
Annals of the New York Academy of Sciences. 557:157-161
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcc9c723ba22147bd1322521b43faf62
https://doi.org/10.1111/j.1749-6632.1989.tb24008.x
https://doi.org/10.1111/j.1749-6632.1989.tb24008.x
Publikováno v:
Blood. 103:301-308
Multiple myeloma (MM) is an incurable form of cancer characterized by accumulation of malignant plasma cells in the bone marrow. During the course of this disease, tumor cells cross endothelial barriers and home to the bone marrow. In latter stages,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::380a35959d56677122db24dacf485172
https://doi.org/10.1182/blood-2003-06-2066
https://doi.org/10.1182/blood-2003-06-2066
Publikováno v:
Oncogene. 21:6791-6800
Cytokine signaling generally occurs through receptors lacking tyrosine kinase activity. Aggregation of receptors leads to activation of receptor associated Janus kinases (Jaks) which in turn phosphorylate members of a family of transcription factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f3581775ca7d28960bd76cb96c8560f
https://doi.org/10.1038/sj.onc.1205815
https://doi.org/10.1038/sj.onc.1205815
Publikováno v:
Blood. 99:4138-4146
In multiple myeloma cells, insulinlike growth factor–I (IGF-I) activates 2 distinct signaling pathways, mitogen-activated protein kinase (MAPK) and phosphoinositol 3-kinase (PI-3K), leading to both proliferative and antiapoptotic effects. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::184a398a6431a12742342df300e49010
https://doi.org/10.1182/blood.v99.11.4138
https://doi.org/10.1182/blood.v99.11.4138
Autor:
Stuart Rudikoff, Nie-Lin Ge
Publikováno v:
Blood. 96:2856-2861
Multiple myeloma (MM) is an invariably fatal disease that accounts for approximately 1% to 2% of all human cancers. Surprisingly little is known about the cellular pathways contributing to growth of these tumors. Although the cytokine interleukin-6 h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a2b5f86c5aa230a06d9051abe8e9659
https://doi.org/10.1182/blood.v96.8.2856.h8002856_2856_2861
https://doi.org/10.1182/blood.v96.8.2856.h8002856_2856_2861
Autor:
Stuart Rudikoff, Nie-Lin Ge
Publikováno v:
Oncogene. 19:4091-4095
Biochemical abnormalities associated with the development of multiple myeloma have been difficult to define especially in terms of demonstrating an in vivo effect of suspected lesions. Herein, we have identified such a defect associated with lack of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::880e77dc6c222b14bda479aeba5197ed
https://doi.org/10.1038/sj.onc.1203801
https://doi.org/10.1038/sj.onc.1203801
Autor:
Ben-hua Sun, Robert L. Jilka, Stuart Rudikoff, Andrew Grey, Maryann Mitnick, Karl L. Insogna, Stavros C. Manolagas, Urszula S. Masiukiewicz
Publikováno v:
Endocrinology. 140:4683-4690
Parathyroid hormone (PTH) exerts its regulatory effects on calcium homeostasis in part by stimulating the release of calcium from the skeleton. PTH stimulates bone resorption indirectly, by inducing the production by stromal/osteoblastic cells of par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12774a5fd193a8ad4d26c68f46ab2d9e
https://doi.org/10.1210/endo.140.10.7036
https://doi.org/10.1210/endo.140.10.7036
Autor:
S. Rao Arepalli, Kirsten Fischer Lindahl, Irene Carlo, Elsy P. Jones, Chyung Ru Wang, Dinah S. Singer, Stuart Rudikoff, T. Kevin Howcroft
Publikováno v:
Immunogenetics. 47:264-271
We cloned, sequenced, and mapped two divergent major histocompatibility class Ib genes from BALB/c mice. M9 d and M10 d both have the potential to encode full-length class I molecules, but transcripts were not readily detectable. M9 is 86% similar to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ac10fcef851211c9306c2316e06f529
https://doi.org/10.1007/s002510050356
https://doi.org/10.1007/s002510050356
Publikováno v:
International Journal of Cancer. 72:892-897
BALB/c peritoneal plasmacytomas induced by a variety of agents are invariably associated with a c-myc translocation. In contrast, naturally arising bone marrow plasma cell tumors in C57BL/KaLwRij mice lack this translocation. This difference has led
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bcb5e6de82bfe629d344ffda96c5802
https://doi.org/10.1002/(sici)1097-0215(19970904)72:5<892::aid-ijc29>3.0.co
https://doi.org/10.1002/(sici)1097-0215(19970904)72:5<892::aid-ijc29>3.0.co