Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Stuart Ratner"'
Autor:
Jennifer B. Jacob, Kuang-Chung Wei, Gerold Bepler, Joyce D. Reyes, Andi Cani, Lisa Polin, Kathryn White, Seongho Kim, Nerissa Viola, Julie McGrath, Anthony Guastella, CongCong Yin, Qing-Shen Mi, Benjamin L. Kidder, Kay-Uwe Wagner, Stuart Ratner, Victoria Phillips, Joanne Xiu, Prahlad Parajuli, Wei-Zen Wei
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106320- (2023)
Summary: HER2-targeted therapy has improved breast cancer survival, but treatment resistance and disease prevention remain major challenges. Genes that enable HER2/Neu oncogenesis are the next intervention targets. A bioinformatics discovery platform
Externí odkaz:
https://doaj.org/article/ef28e19612ea43f89c00bb93371e0760
Autor:
Shari Pilon-Thomas, Joyce D. Reyes, Jay A. Berzofsky, Jennifer B. Jacob, Gregory Dyson, Hoyoung Maeng, Kuang Chung Wei, Stuart Ratner, Jeffrey A. Frelinger, Heather M. Gibson, Wei Zen Wei
Publikováno v:
J Immunol
The genetic basis and mechanisms of disparate antitumor immune response was investigated in Diversity Outbred (DO) F1 mice that express human HER2. DO mouse stock samples nearly the entire genetic repertoire of the species. We crossed DO mice with sy
Autor:
Kang Chen, Heather M. Gibson, Joyce D. Reyes, Richard F. Jones, Stuart Ratner, Wei-Zen Wei, Ulka N. Vaishampayan, Jennifer B. Jacob
Publikováno v:
Cancer Immunol Immunother
Enhancement of endogenous immunity to tumor-associated self-antigens and neoantigens is the goal of preventive vaccination. Toward this goal, we compared the efficacy of the following HER2 DNA vaccine constructs: vaccines encoding wild-type HER2, hyb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7448ad4144a6977fca7e610a6f76b47a
https://europepmc.org/articles/PMC6586491/
https://europepmc.org/articles/PMC6586491/
Publikováno v:
Journal of Leukocyte Biology. 69:675-683
Ikaros family members play critical roles in hematopoietic development, yet molecules regulated by Ikaros proteins remain incompletely characterized. To determine the requirements for functional Ikaros proteins, we overexpressed Ik7, a dominant negat
Publikováno v:
Toxicological Sciences. 33:129-139
The effects of topically applied 12-O-tetradecanoylphorbol-13-acetate (TPA), acetone, and ethanol on systemic immune function were analyzed in SSIN mice. A total of one, four, or eight dorsal applications of solvent (50-300 microl/treatment, 2x/week)
Publikováno v:
Carcinogenesis. 17:2617-2624
SSIN mice are considerably more sensitive to the effects of 12-O-tetradecanoylphorbol-13-acetate (TPA) in two-stage skin carcinogenesis protocols than are most other strains and stocks of mice. Experiments were performed to determine whether there wa
Autor:
Stuart Ratner, Peter A. Lalley, Linea L. Rydstedt, Sandra R. Wolman, Gary B. Talpos, Marille E. Herrmann
Publikováno v:
Cancer Genetics and Cytogenetics. 75:111-116
Adrenocortical tumors are detected with increasing frequency, but symptomatic cases with excessive hormone production are rare. We investigated cytogenetically one benign aldosterone-producing tumor (Conn Syndrome)(case 1) and one malignant cortisol-
Autor:
Stuart Ratner
Publikováno v:
JNCI Journal of the National Cancer Institute. 82:612-616
Murine splenic lymphocytes nonspecifically stimulated with recombinant human interleukin-2 in vitro were fractionated according to their ability to migrate through type I collagen gel during a 24-hour period. After labeling with 111In and adoptive tr
Autor:
Stuart Ratner, Peter A. Lalley, Anwar N. Mohamed, Katrina T. Trevor, Linea L. Rydstedt, Sandra R. Wolman, Marille E. Herrmann, Gary B. Talpos
Publikováno v:
Cancer genetics and cytogenetics. 67(1)
Results of cell culture and cytogenetic analysis (standard and fluorescent in situ hybridization, FISH) of two sporadic gastrinomas are reported. Maintenance of hormonal activity was assessed by detection of gastrin levels during the first 3 months i
Publikováno v:
Blood. 104:2360-2360
Multiple myeloma (MM) cell adhesion to fibronectin (FN), mediated via VLA-4 and VLA-5, has been shown to induce resistance to several chemotherapeutic drugs. Disruption of MM cell adhesion to FN and other marrow microenvironment elements might theref