Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Stuart Ratner"'
Autor:
Jennifer B. Jacob, Kuang-Chung Wei, Gerold Bepler, Joyce D. Reyes, Andi Cani, Lisa Polin, Kathryn White, Seongho Kim, Nerissa Viola, Julie McGrath, Anthony Guastella, CongCong Yin, Qing-Shen Mi, Benjamin L. Kidder, Kay-Uwe Wagner, Stuart Ratner, Victoria Phillips, Joanne Xiu, Prahlad Parajuli, Wei-Zen Wei
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106320- (2023)
Summary: HER2-targeted therapy has improved breast cancer survival, but treatment resistance and disease prevention remain major challenges. Genes that enable HER2/Neu oncogenesis are the next intervention targets. A bioinformatics discovery platform
Externí odkaz:
https://doaj.org/article/ef28e19612ea43f89c00bb93371e0760
Autor:
Shari Pilon-Thomas, Joyce D. Reyes, Jay A. Berzofsky, Jennifer B. Jacob, Gregory Dyson, Hoyoung Maeng, Kuang Chung Wei, Stuart Ratner, Jeffrey A. Frelinger, Heather M. Gibson, Wei Zen Wei
Publikováno v:
J Immunol
The genetic basis and mechanisms of disparate antitumor immune response was investigated in Diversity Outbred (DO) F1 mice that express human HER2. DO mouse stock samples nearly the entire genetic repertoire of the species. We crossed DO mice with sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee1cfc94d83cdb64858a9aa4a51db8f
https://pubmed.ncbi.nlm.nih.gov/32796024
https://pubmed.ncbi.nlm.nih.gov/32796024
Autor:
Kang Chen, Heather M. Gibson, Joyce D. Reyes, Richard F. Jones, Stuart Ratner, Wei-Zen Wei, Ulka N. Vaishampayan, Jennifer B. Jacob
Publikováno v:
Cancer Immunol Immunother
Enhancement of endogenous immunity to tumor-associated self-antigens and neoantigens is the goal of preventive vaccination. Toward this goal, we compared the efficacy of the following HER2 DNA vaccine constructs: vaccines encoding wild-type HER2, hyb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7448ad4144a6977fca7e610a6f76b47a
https://europepmc.org/articles/PMC6586491/
https://europepmc.org/articles/PMC6586491/
Publikováno v:
Cellular Immunology. 233:1-10
Adoptive immunotherapy is hampered by poor lymphocyte localization in tumors. The polarized, adhesive phenotype of activated lymphocytes may contribute to this problem by making the cells prone to trapping and damage in pulmonary microvasculature. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b28ee4dc609094c3545cf5def1f732e9
https://doi.org/10.1016/j.cellimm.2004.12.009
https://doi.org/10.1016/j.cellimm.2004.12.009
Publikováno v:
Journal of Leukocyte Biology. 69:675-683
Ikaros family members play critical roles in hematopoietic development, yet molecules regulated by Ikaros proteins remain incompletely characterized. To determine the requirements for functional Ikaros proteins, we overexpressed Ik7, a dominant negat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f9b7ea7c306e694c8a4cc60d89cdbca
https://doi.org/10.1189/jlb.69.4.675
https://doi.org/10.1189/jlb.69.4.675
Publikováno v:
Toxicological Sciences. 33:129-139
The effects of topically applied 12-O-tetradecanoylphorbol-13-acetate (TPA), acetone, and ethanol on systemic immune function were analyzed in SSIN mice. A total of one, four, or eight dorsal applications of solvent (50-300 microl/treatment, 2x/week)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69415a3b9904cc81d13f4d1aa4094312
https://doi.org/10.1093/toxsci/33.1.129
https://doi.org/10.1093/toxsci/33.1.129
Publikováno v:
Carcinogenesis. 17:2617-2624
SSIN mice are considerably more sensitive to the effects of 12-O-tetradecanoylphorbol-13-acetate (TPA) in two-stage skin carcinogenesis protocols than are most other strains and stocks of mice. Experiments were performed to determine whether there wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a26c8addafd59056214999ba9411cd20
https://doi.org/10.1093/carcin/17.12.2617
https://doi.org/10.1093/carcin/17.12.2617
Autor:
Stuart Ratner, Peter A. Lalley, Linea L. Rydstedt, Sandra R. Wolman, Gary B. Talpos, Marille E. Herrmann
Publikováno v:
Cancer Genetics and Cytogenetics. 75:111-116
Adrenocortical tumors are detected with increasing frequency, but symptomatic cases with excessive hormone production are rare. We investigated cytogenetically one benign aldosterone-producing tumor (Conn Syndrome)(case 1) and one malignant cortisol-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::588aa2d75d0462fd7df69079e7ebddb7
https://doi.org/10.1016/0165-4608(94)90161-9
https://doi.org/10.1016/0165-4608(94)90161-9
Autor:
Stuart Ratner
Publikováno v:
JNCI Journal of the National Cancer Institute. 82:612-616
Murine splenic lymphocytes nonspecifically stimulated with recombinant human interleukin-2 in vitro were fractionated according to their ability to migrate through type I collagen gel during a 24-hour period. After labeling with 111In and adoptive tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64916e6b955913479d0664bc1ba4587c
https://doi.org/10.1093/jnci/82.7.612
https://doi.org/10.1093/jnci/82.7.612
Publikováno v:
Journal of immunological methods. 258(1-2)
Cytotoxic T cells (CTL) are readily activated by immunogenic peptides and they exert potent anti-tumor activity if the same peptides are displayed on class I major histocompatibility complex (MHC) of the tumor cells. A handful of tumor-associated ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::985bd3ba2f26b39cad0763529052a415
https://pubmed.ncbi.nlm.nih.gov/11684131
https://pubmed.ncbi.nlm.nih.gov/11684131