Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Stuart R. Pierce"'
Autor:
Stuart R. Pierce, Ziwei Fang, Yajie Yin, Lindsay West, Majdouline Asher, Tianran Hao, Xin Zhang, Katherine Tucker, Allison Staley, Yali Fan, Wenchuan Sun, Dominic T. Moore, Chang Xu, Yi-Hsuan Tsai, Joel Parker, Varun Vijay Prabhu, Joshua E. Allen, Douglas Lee, Chunxiao Zhou, Victoria Bae-Jump
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-15 (2021)
Abstract Background ONC201 is a dopamine receptor D2 (DRD2) antagonist that inhibits tumor growth in preclinical models through ClpP activation to induce integrated stress response pathway and mitochondrial events related to inhibition of cell growth
Externí odkaz:
https://doaj.org/article/0bf0764955fb4c44a847f4becd71ad3c
Autor:
Yali Fan, Jiandong Wang, Ziwei Fang, Stuart R. Pierce, Lindsay West, Allison Staley, Katherine Tucker, Yajie Yin, Wenchuan Sun, Weimin Kong, Varun Prabhu, Joshua E. Allen, Chunxiao Zhou, Victoria L. Bae-Jump
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
ONC201 is a promising first-in-class small molecule that has been reported to have anti-neoplastic activity in various types of cancer through activation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) as well as activation of mito
Externí odkaz:
https://doaj.org/article/f870a873615e49cebee45b48e7cb0d1e
Autor:
Ziwei, Fang, Jiandong, Wang, Leslie H, Clark, Wenchuan, Sun, Yajie, Yin, Weimin, Kong, Stuart R, Pierce, Lindsay, West, Stephanie A, Sullivan, Arthur-Quan, Tran, Varun V, Prabhu, Chunxiao, Zhou, Victoria, Bae-Jump
Publikováno v:
American journal of cancer research. 8(8)
Uterine serous carcinoma (USC) represents an aggressive histologic subtype of endometrial cancer. It is associated with a poor prognosis, and improved therapies for women battling USCs are greatly needed. ONC201 is an orally bioavailable, first-in-cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::68a3f877ceb0c69b9b7fb3d4145b1192
https://pubmed.ncbi.nlm.nih.gov/30210923
https://pubmed.ncbi.nlm.nih.gov/30210923