Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Stuart Purbrick"'
Autor:
Claire M. Patterson, Srividya B. Balachander, Iain Grant, Petar Pop-Damkov, Brian Kelly, William McCoull, Jeremy Parker, Michael Giannis, Kathryn J. Hill, Francis D. Gibbons, Edward J. Hennessy, Paul Kemmitt, Alexander R. Harmer, Sonya Gales, Stuart Purbrick, Sean Redmond, Matthew Skinner, Lorraine Graham, J. Paul Secrist, Alwin G. Schuller, Shenghua Wen, Ammar Adam, Corinne Reimer, Justin Cidado, Martin Wild, Eric Gangl, Stephen E. Fawell, Jamal Saeh, Barry R. Davies, David J. Owen, Marianne B. Ashford
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Claire Patterson et al. present the design and development of AZD0466, a drug-dendrimer conjugate, and use preclinical and mathematical models to determine the optimal release rate of the drug from the dendrimer carrier for maximal therapeutic index
Externí odkaz:
https://doaj.org/article/722de1f4d6464ec9a94bce51fe4fc356
Autor:
Ammar Adam, David J. Owen, Justin Cidado, Claire Patterson, Matthew Skinner, Stuart Purbrick, Lorraine Graham, Petar Pop-Damkov, Michael Giannis, Srividya B. Balachander, Francis D. Gibbons, William McCoull, Marianne Ashford, Hill Kathryn Jane, Martin Wild, Eric Gangl, Stephen Fawell, Corinne Reimer, Sean Redmond, Paul D. Kemmitt, Barry R. Davies, Jamal Carlos Saeh, Shenghua Wen, J. Paul Secrist, Alwin Schuller, Edward J. Hennessy, Sonya Gales, Iain Grant, Alexander R. Harmer, Jeremy S. Parker, Brian Kelly
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Dual Bcl-2/Bcl-xL inhibitors are expected to deliver therapeutic benefit in many haematological and solid malignancies, however, their use is limited by tolerability issues. AZD4320, a potent dual Bcl-2/Bcl-xL inhibitor, has shown good efficacy howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f928851dba9fe7a39b683d8c12e8a5d
https://doi.org/10.1038/s42003-020-01631-8
https://doi.org/10.1038/s42003-020-01631-8
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 99:106595
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f004ab2a1f295b11e49a8754449117d
https://doi.org/10.1016/j.vascn.2019.05.120
https://doi.org/10.1016/j.vascn.2019.05.120
Autor:
Stuart Purbrick, Louise Sladen, Mike Rolf, Madeleine Antonsson, Regina Fritsche-Danielson, Martin Billger
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 93:151
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9323c5fb0577fdbe4f52517aeb0048cf
https://doi.org/10.1016/j.vascn.2018.01.497
https://doi.org/10.1016/j.vascn.2018.01.497
Publikováno v:
Toxicology Letters. 229:S219-S220
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e47d9adf7a6523cddb386cc030fc544
https://doi.org/10.1016/j.toxlet.2014.06.737
https://doi.org/10.1016/j.toxlet.2014.06.737
Autor:
Richard J, Davis, Colin E, Murdoch, Mozam, Ali, Stuart, Purbrick, Rivka, Ravid, Gordon S, Baxter, Nick, Tilford, Robert L G, Sheldrick, Kenneth L, Clark, Robert A, Coleman
Publikováno v:
British journal of pharmacology. 141(4)
1. Dilatation of the cerebral vasculature is recognised to be involved in the pathophysiology of migraine. Furthermore, elevated levels of prostaglandin E(2) (PGE(2)) occur in the blood, plasma and saliva of migraineurs during an attack, suggestive o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::999c673fbe9de92b69cb1c2ae59886bf
https://pubmed.ncbi.nlm.nih.gov/14744815
https://pubmed.ncbi.nlm.nih.gov/14744815
Autor:
Stephen Jordan, Stuart Purbrick, Peter Davies, Adam French, Ken Meecham, Victoria Milner, Emma Peake, Simon Moore, Deborah Jones, David Butler
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 66:183-184
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0af1ff9f58af0c36e49f801ba7a930b7
https://doi.org/10.1016/j.vascn.2012.08.088
https://doi.org/10.1016/j.vascn.2012.08.088
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 58:171-172
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f60df3a1a254713cd237108cb5a37d92
https://doi.org/10.1016/j.vascn.2008.05.105
https://doi.org/10.1016/j.vascn.2008.05.105
Autor:
Ken Meecham, Jean-Pierre Valentin, Pierre Lainee, Michelle Coulson, Joanne Bowes, Helen Prior, Stuart Purbrick
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 66:186
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51cc1998cea6810f34676e7c4946f7da
https://doi.org/10.1016/j.vascn.2012.08.098
https://doi.org/10.1016/j.vascn.2012.08.098
Autor:
Ken Meecham, Stuart Purbrick
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 60:217
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bac229e03a4c2d5ba566e2ebc8cb639a
https://doi.org/10.1016/j.vascn.2009.04.045
https://doi.org/10.1016/j.vascn.2009.04.045