Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Stuart Marshall-Clarke"'
Autor:
Joan E. Downes, Stuart Marshall-Clarke
Publikováno v:
Immunology. 131:513-524
Haematopoiesis is crucial for immunity because it results in the production of leucocytes. Bacterial and viral infections alter leucocyte production by promoting granulopoiesis or lymphopoiesis. Recent studies suggest that changes in leucocyte produc
Autor:
Joanne L. Pennock, Richard K. Grencis, Paul Rothwell, Joan E. Downes, Andrew G. Bowie, Ismar R. Haga, Stuart Marshall-Clarke, Persephone Borrow
Publikováno v:
Journal of Biological Chemistry. 282:24759-24766
Innate immune responses are critical in controlling viral infections. Viral proteins and nucleic acids have been shown to be recognized by pattern recognition receptors of the Toll-like receptor (TLR) family, triggering downstream signaling cascades
Publikováno v:
Nature Reviews Immunology. 4:553-564
The past decade has brought great strides in our understanding of adaptive immunity in neonatal mice. Although poor immune responses are commonly observed, it is now clear that mature function can be achieved by all arms of the adaptive immune system
Publikováno v:
Immunology. 109:102-108
Constitutive expression of major histocompatibility complex class II molecules (MHC II) is restricted to dendritic cells, cells of the macrophage lineage and B lymphocytes. In all three lineages, peptide fragments of captured antigen are loaded into
Publikováno v:
Immunology. 100:141-151
Mature B lymphocytes respond to antigen receptor ligation by phenotypic changes, including up-regulation of major histocompatibility complex class II molecules and expression of B7.2, which are required for initiating and sustaining a productive inte
Autor:
Stuart Marshall-Clarke, Lynn Tasker
Publikováno v:
Immunology. 99:385-393
Summary Ligation of membrane immunoglobulin M (mIgM) induces cell cycle arrest and apoptosis in the WEHI 231 B-lymphoma cell line. The molecular mechanisms which link receptor ligation and the nuclear events that underlie this response, have yet to b
Publikováno v:
Immunology Today. 21:35-41
Recent experiments have led to renewed interest in differences between immune responses in adults and neonates. Here, Stuart Marshall-Clarke and colleagues discuss and propose a model suggesting that differences at the B-cell level might play an impo
Publikováno v:
Immunology. 87:624-632
Ligation of surface immunoglobulin (sIg) on certain murine B-lymphoma lines has been shown to initiate a programme leading to growth arrest and death of the cells by apoptosis. The cell lines WEHI 231 and CH33 which respond in this way to receptor cr
Publikováno v:
Immunology. 131(4)
Haematopoiesis is crucial for immunity because it results in the production of leucocytes. Bacterial and viral infections alter leucocyte production by promoting granulopoiesis or lymphopoiesis. Recent studies suggest that changes in leucocyte produc
Autor:
Stuart Marshall–Clarke, Jonathan M. Rhodes, A McGoldrick, Carol L. Roberts, Chiedzo Mpofu, Andrew Cross, Steven W. Edwards, C. Anthony Hart, Sreedhar Subramanian, Barry J. Campbell
Publikováno v:
Gastroenterology. 133(5)
Crohn's disease (CD) is mimicked by inherited phagocyte disorders and is associated with circulating antibodies against yeast mannan (anti-Saccharomyces cerevisiae antibody; ASCA). We speculated that mannans might impair phagocyte function.S cerevisi