Výsledky vyhledávání - "Stuart M. Stocks"

Aerobic bioreactors: condensers, evaporation rates, scale-up and scale-down

Publikováno v: Biotechnology letters. 44(7)

Hydrodynamics, mixing and shear are terms often used when explaining or modelling scale differences, but other scale differences, such as evaporation, can arise from non-hydrodynamic factors that can be managed with some awareness and effort.We prese

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::af9a7326aaa7daeca9d7922f6a8e6e30
https://pubmed.ncbi.nlm.nih.gov/35650455

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Solubility Prediction of Different Forms of Pharmaceuticals in Single and Mixed Solvents Using Symmetric Electrolyte Nonrandom Two-Liquid Segment Activity Coefficient Model

Autor: Michael Frederick Freitag, Kim Troensegaard Nielsen, Gürkan Sin, Getachew Shibabaw Molla, Stuart M. Stocks

Publikováno v: Industrial & Engineering Chemistry Research. 58:4267-4276

An improved framework has been developed for solubility prediction of different forms of a medium-sized antibiotic (i.e., nonelectrolyte, electrolyte, and solvate) in single and mixed solvents using a symmetrically reformulated electrolyte nonrandom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5a94be564d7916c0482cb01a21547c51
https://doi.org/10.1021/acs.iecr.8b04268

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Independent Validation of an In Silico Tool for a Pilot-Scale Pharmaceutical Crystallization Process Development

Autor: Gürkan Sin, Francis Tran, Stuart M. Stocks, Jens Abildskov, Gitte Holm Jensen, Merve Öner, Tim Ståhlberg, Kirsten Bisgaard-Frantzen

Publikováno v: Processes, Vol 9, Iss 640, p 640 (2021)
Processes
Volume 9
Issue 4
Öner, M, Tran, F, Jensen, G H, Ståhlberg, T, Bisgaard-Frantzen, K, Stocks, S M, Abildskov, J & Sin, G 2021, ' Independent Validation of an In Silico Tool for a Pilot-Scale Pharmaceutical Crystallization Process Development ', Processes, vol. 9, no. 4, 640 . https://doi.org/10.3390/pr9040640

There are many published models for predicting crystal size distribution (CSD) in the literature. However, none of them have been independently and comprehensively tested, which is important for industrial acceptance and confidence of these models. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4e43316f22c67f54b30ff8b991b9ea6
https://www.mdpi.com/2227-9717/9/4/640

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Comprehensive evaluation of a data driven control strategy:Experimental application to a pharmaceutical crystallization process

Autor: Tim Ståhlberg, Gürkan Sin, Johan Eriksson Bajtner, Frederico C. C. Montes, Stuart M. Stocks, Merve Öner

Publikováno v: Öner, M, Montes, F C C, Ståhlberg, T, Stocks, S M, Bajtner, J E & Sin, G 2020, ' Comprehensive evaluation of a data driven control strategy : Experimental application to a pharmaceutical crystallization process ', Chemical Engineering Research and Design, vol. 163, pp. 248-261 . https://doi.org/10.1016/j.cherd.2020.08.032

In this contribution, a data-driven control approach was developed and applied experimentally to a pharmaceutical batch cooling crystallization process. In this approach, a radial basis functions (RBF) network model was trained in real-time with expe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2cb6518da049529a152034ad0240116
https://orbit.dtu.dk/en/publications/860ebdbd-7f00-4708-84b5-10ced29869ee

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Mechanistic Fermentation Models for Process Design, Monitoring, and Control

Autor: Krist V. Gernaey, Lisa Mears, Gürkan Sin, Stuart M. Stocks, Mads Orla Albæk

Publikováno v: Trends in Biotechnology. 35:914-924

Mechanistic models require a significant investment of time and resources, but their application to multiple stages of fermentation process development and operation can make this investment highly valuable. This Opinion article discusses how an esta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cb556e05aa5217919d438d8ad910188
https://doi.org/10.1016/j.tibtech.2017.07.002

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A novel model-based control strategy for aerobic filamentous fungal fed-batch fermentation processes

Autor: Lisa Mears, Krist V. Gernaey, Benny Cassells, Stuart M. Stocks, Gürkan Sin, Mads Orla Albæk

Publikováno v: Biotechnology and Bioengineering. 114:1459-1468

A novel model-based control strategy has been developed for filamentous fungal fed-batch fermentation processes. The system of interest is a pilot scale (550 L) filamentous fungus process operating at Novozymes A/S. In such processes, it is desirable

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::10aa419b7a65fa7b5bac8d3e0df5e9f8
https://doi.org/10.1002/bit.26274

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